Search Results - "Klosowska, Kamila"
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Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system
Published in PloS one (28-03-2018)“…Deciphering a function of a given protein requires investigating various biological aspects. Usually, the protein of interest is expressed with a fusion tag…”
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Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings
Published in iScience (24-09-2021)“…Processive exoribonucleases are executors of RNA decay. In humans, their physical but not functional interactions were thoughtfully investigated. Here we have…”
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A new strategy for gene targeting and functional proteomics using the DT40 cell line
Published in Nucleic acids research (01-09-2013)“…DT40 cells derived from chicken B lymphocytes exhibit exceptionally high homologous recombination rates. Therefore, they can be used as a convenient tool and…”
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Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA
Published in Nucleic acids research (04-06-2020)“…RNA decay is a key element of mitochondrial RNA metabolism. To date, the only well-documented machinery that plays a role in mtRNA decay in humans is the…”
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