Search Results - "Klose, Jack"

Unraveling DNA Triplex Assembly: Mass Spectrometric Investigation of Modified Triplex Forming Oligonucleotides for Enhanced Gene Targeting by Chandrasegaran, Sarveenah, Klose, Jack W., Pukala, Tara L.

“…Deoxyribonucleic acid triplexes have potential roles in a range of biological processes involving gene and transcriptional regulation. A major challenge in…”
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Native Mass Spectrometric Insights into the Formation and Stability of DNA Triplexes by Klose, Jack W., Begbie, Alexander J., Toronjo-Urquiza, Luis, Pukala, Tara L.

“…Deoxyribonucleic acid is a genetic biomacromolecule that contains the inherited information required to build and maintain a living organism. While the…”
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Escherichia coli YgiC and YjfC Possess PeptideSpermidine Ligase Activity by Pederick, Jordan L., Klose, Jack, Jovcevski, Blagojce, Pukala, Tara L., Bruning, John B.

“…Polyamines and polyamine-containing metabolites are involved in many cellular processes related to bacterial cell growth and survival. In Escherichia coli, the…”
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Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism by Pederick, Jordan L., Horsfall, Aimee J., Jovcevski‬, Blagojce, Klose, Jack, Abell, Andrew D., Pukala, Tara L., Bruning, John B.

“…Enzymes involved in Staphylococcus aureus amino acid metabolism have recently gained traction as promising targets for the development of new antibiotics,…”
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