Search Results - "Kloet, Frans M."

Lipidomics of familial longevity by Gonzalez‐Covarrubias, Vanessa, Beekman, Marian, Uh, Hae‐Won, Dane, Adrie, Troost, Jorne, Paliukhovich, Iryna, Kloet, Frans M., Houwing‐Duistermaat, Jeanine, Vreeken, Rob J., Hankemeier, Thomas, Slagboom, Eline P.

“…Summary Middle‐aged offspring of nonagenarians, as compared to their spouses (controls), show a favorable lipid metabolism marked by larger LDL particle size…”
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Analytical Error Reduction Using Single Point Calibration for Accurate and Precise Metabolomic Phenotyping by van der Kloet, Frans M, Bobeldijk, Ivana, Verheij, Elwin R, Jellema, Renger H

“…Analytical errors caused by suboptimal performance of the chosen platform for a number of metabolites and instrumental drift are a major issue in large-scale…”
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Performance of methods that separate common and distinct variation in multiple data blocks by Måge, Ingrid, Smilde, Age K., Kloet, Frans M.

“…In many areas of science, multiple sets of data are collected from the samples. Such data sets can be analyzed by multiblock (or data fusion) methods. The aim…”
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Increased comparability between RNA-Seq and microarray data by utilization of gene sets by van der Kloet, Frans M, Buurmans, Jeroen, Jonker, Martijs J, Smilde, Age K, Westerhuis, Johan A

“…The field of transcriptomics uses and measures mRNA as a proxy of gene expression. There are currently two major platforms in use for quantifying mRNA,…”
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Natural variation in wild tomato trichomes; selecting metabolites that contribute to insect resistance using a random forest approach by Kortbeek, Ruy W. J, Galland, Marc D, Muras, Aleksandra, van der Kloet, Frans M, André, Bart, Heilijgers, Maurice, van Hijum, Sacha A. F. T, Haring, Michel A, Schuurink, Robert C, Bleeker, Petra M

“…Abstract Background Plant-produced specialised metabolites are a powerful part of a plant’s first line of defence against herbivorous insects, bacteria and…”
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Why orthogonal rotations might be not so orthogonal as you think by Hoefsloot, Huub C.J., Kloet, Frans M., Westerhuis, Johan A.

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Nutrikinetic modeling reveals order of genistein phase II metabolites appearance in human plasma by Smit, Suzanne, Szymańska, Ewa, Kunz, Iris, Roldan, Victoria Gomez, Tilborg, Marcel W. E. M, Weber, Peter, Prudence, Kevin, Kloet, Frans M, Duynhoven, John P. M, Smilde, Age K, Vos, Ric C. H, Bendik, Igor

“…SCOPE: Genistein from foods or supplements is metabolized by the gut microbiota and the human body, thereby releasing many different metabolites into systemic…”
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Semi-automated non-target processing in GC × GC-MS metabolomics analysis: applicability for biomedical studies by Koek, Maud M, van der Kloet, Frans M, Kleemann, Robert, Kooistra, Teake, Verheij, Elwin R, Hankemeier, Thomas

“…Due to the complexity of typical metabolomics samples and the many steps required to obtain quantitative data in GC × GC-MS consisting of deconvolution, peak…”
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Adult GAMT deficiency: A literature review and report of two siblings by Modi, Bhavi P., Khan, Haq Nawaz, van der Lee, Robin, Wasim, Muhammad, Haaxma, Charlotte A., Richmond, Phillip A., Drögemöller, Britt, Shah, Suleman, Salomons, Gajja, van der Kloet, Frans M., Vaz, Fred M., van der Crabben, Saskia N., Ross, Colin J., Wasserman, Wyeth W., van Karnebeek, Clara D.M., Awan, Fazli Rabbi

“…Guanidinoacetate methyltransferase (GAMT) deficiency is a creatine deficiency disorder and an inborn error of metabolism presenting with progressive…”
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Separating common from distinctive variation by van der Kloet, Frans M, Sebastián-León, Patricia, Conesa, Ana, Smilde, Age K, Westerhuis, Johan A

“…Joint and individual variation explained (JIVE), distinct and common simultaneous component analysis (DISCO) and O2-PLS, a two-block (X-Y) latent variable…”
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Matrix Effect Compensation in Small-Molecule Profiling for an LC–TOF Platform Using Multicomponent Postcolumn Infusion by González, Oskar, van Vliet, Michael, Damen, Carola W. N, van der Kloet, Frans M, Vreeken, Rob J, Hankemeier, Thomas

“…The possible presence of matrix effect is one of the main concerns in liquid chromatography–mass spectrometry (LC–MS)-driven bioanalysis due to its impact on…”
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A new approach to untargeted integration of high resolution liquid chromatography–mass spectrometry data by van der Kloet, Frans M., Hendriks, Margriet, Hankemeier, Thomas, Reijmers, Theo

“…•We introduce a new method for untargeted feature extraction and integration.•Few parameters are needed to configure method.•Feature extraction and integration…”
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A new approach to untargeted integration of high resolution liquid chromatography-mass spectrometry data by Kloet, Frans M van der, Hendriks, Margriet, Hankemeier, Thomas, Reijmers, Theo

“…Because of its high sensitivity and specificity, hyphenated mass spectrometry has become the predominant method to detect and quantify metabolites present in…”
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