Search Results - "Klöckner, Anna"

Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane by Sabnis, Akshay, Hagart, Katheryn Lh, Klöckner, Anna, Becce, Michele, Evans, Lindsay E, Furniss, R Christopher D, Mavridou, Despoina Ai, Murphy, Ronan, Stevens, Molly M, Davies, Jane C, Larrouy-Maumus, Gérald J, Clarke, Thomas B, Edwards, Andrew M

“…Colistin is an antibiotic of last resort, but has poor efficacy and resistance is a growing problem. Whilst it is well established that colistin disrupts the…”
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Targeting a cell wall biosynthesis hot spot by Müller, Anna, Klöckner, Anna, Schneider, Tanja

“…Covering: up to 2017History points to the bacterial cell wall biosynthetic network as a very effective target for antibiotic intervention, and numerous natural…”
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Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids by Grein, Fabian, Müller, Anna, Scherer, Katharina M., Liu, Xinliang, Ludwig, Kevin C., Klöckner, Anna, Strach, Manuel, Sahl, Hans-Georg, Kubitscheck, Ulrich, Schneider, Tanja

“…The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-positive pathogens, such as methicillin resistant Staphylococcus…”
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Controlled Dendrimersome Nanoreactor System for Localized Hypochlorite-Induced Killing of Bacteria by Potter, Michael, Najer, Adrian, Klöckner, Anna, Zhang, Shaodong, Holme, Margaret N, Nele, Valeria, Che, Junyi, Massi, Lucia, Penders, Jelle, Saunders, Catherine, Doutch, James J, Edwards, Andrew M, Ces, Oscar, Stevens, Molly M

“…Antibiotic resistance is a serious global health problem necessitating new bactericidal approaches such as nanomedicines. Dendrimersomes (DSs) have recently…”
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Chlamydia-Related Bacteria in Free-Living and Captive Great Apes, Gabon by Klöckner, Anna, Nagel, Michael, Greub, Gilbert, Aeby, Sébastien, Hoffmann, Karolin, Liégeois, Florian, Rouet, Francois, De Benedetti, Stefania, Borel, Nicole, Henrichfreise, Beate

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Bacterial Toxin‐Triggered Release of Antibiotics from Capsosomes Protects a Fly Model from Lethal Methicillin‐Resistant Staphylococcus aureus (MRSA) Infection by Tonkin, Renée L., Klöckner, Anna, Najer, Adrian, Simoes da Silva, Carolina J., Echalier, Cécile, Dionne, Marc S., Edwards, Andrew M., Stevens, Molly M.

“…Antibiotic resistance is a severe global health threat and hence demands rapid action to develop novel therapies, including microscale drug delivery systems…”
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AmiD Is a Novel Peptidoglycan Amidase in Wolbachia Endosymbionts of Drosophila melanogaster by Wilmes, Miriam, Meier, Kirstin, Schiefer, Andrea, Josten, Michaele, Otten, Christian F, Klöckner, Anna, Henrichfreise, Beate, Vollmer, Waldemar, Hoerauf, Achim, Pfarr, Kenneth

“…endobacteria are obligate intracellular bacteria with a highly reduced genome infecting many arthropod and filarial species, in which they manipulate arthropod…”
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AmiA is a penicillin target enzyme with dual activity in the intracellular pathogen Chlamydia pneumoniae by Klöckner, Anna, Otten, Christian, Derouaux, Adeline, Vollmer, Waldemar, Bühl, Henrike, De Benedetti, Stefania, Münch, Daniela, Josten, Michaele, Mölleken, Katja, Sahl, Hans-Georg, Henrichfreise, Beate

“…Intracellular Chlamydiaceae do not need to resist osmotic challenges and a functional cell wall was not detected in these pathogens. Nevertheless, a recent…”
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The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular Chlamydia and Wolbachia and Break the Persistence Phenotype in Chlamydia by Löckener, Iris, Behrmann, Lara Vanessa, Reuter, Jula, Schiefer, Andrea, Klöckner, Anna, Krannich, Sebastian, Otten, Christian, Mölleken, Katja, Ichikawa, Satoshi, Hoerauf, Achim, Schneider, Tanja, Pfarr, Kenneth M, Henrichfreise, Beate

“…Chlamydial infections and diseases caused by filarial nematodes are global health concerns. However, treatment presents challenges due to treatment failures…”
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Co-solvents as stabilizing agents during heterologous overexpression in Escherichia coli - application to chlamydial penicillin-binding protein 6 by Otten, Christian, De Benedetti, Stefania, Gaballah, Ahmed, Bühl, Henrike, Klöckner, Anna, Brauner, Jarryd, Sahl, Hans-Georg, Henrichfreise, Beate

“…Heterologous overexpression of foreign proteins in Escherichia coli often leads to insoluble aggregates of misfolded inactive proteins, so-called inclusion…”
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Sulfide Protects Staphylococcus aureus from Aminoglycoside Antibiotics but Cannot Be Regarded as a General Defense Mechanism against Antibiotics by Weikum, Julia, Ritzmann, Niklas, Jelden, Nils, Klöckner, Anna, Herkersdorf, Sebastian, Josten, Michaele, Sahl, Hans-Georg, Grein, Fabian

“…Sulfide production has been proposed to be a universal defense mechanism against antibiotics in bacteria (K. Shatalin, E. Shatalina, A. Mironov, and E. Nudler,…”
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Assessing the impact of silicon nanowires on bacterial transformation and viability of Escherichia coli by Becce, Michele, Klöckner, Anna, Higgins, Stuart G, Penders, Jelle, Hachim, Daniel, Bashor, Caleb J, Edwards, Andrew M, Stevens, Molly M

“…We investigated the biomaterial interface between the bacteria Escherichia coli DH5α and silicon nanowire patterned surfaces. We optimised the engineering of…”
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The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular IChlamydia/I and IWolbachia/I and Break the Persistence Phenotype in IChlamydia/I by Löckener, Iris, Behrmann, Lara Vanessa, Reuter, Jula, Schiefer, Andrea, Klöckner, Anna, Krannich, Sebastian, Otten, Christian, Mölleken, Katja, Ichikawa, Satoshi, Hoerauf, Achim, Schneider, Tanja, Pfarr, Kenneth M, Henrichfreise, Beate

“…Chlamydial infections and diseases caused by filarial nematodes are global health concerns. However, treatment presents challenges due to treatment failures…”
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Antimicrobial Dialkylresorcins from Marine-Derived Microorganisms: Insights into Their Mode of Action and Putative Ecological Relevance by Harms, Henrik, Klöckner, Anna, Schrör, Jan, Josten, Michaele, Kehraus, Stefan, Crüsemann, Max, Hanke, Wiebke, Schneider, Tanja, Schäberle, Till F, König, Gabriele M

“…has been reported as a seaweed-associated or marine-derived species with largely unknown secondary metabolites. The combination of bioinformatic analysis and…”
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Deconstructing the Chlamydial Cell Wall by Klöckner, Anna, Bühl, Henrike, Viollier, Patrick, Henrichfreise, Beate

“…The evolutionary separated Gram-negative Chlamydiales show a biphasic life cycle and replicate exclusively within eukaryotic host cells. Members of the genus…”
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Ca 2+ -Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids by Grein, Fabian, Müller, Anna, Scherer, Katharina M, Liu, Xinliang, Ludwig, Kevin C, Klöckner, Anna, Strach, Manuel, Sahl, Hans-Georg, Kubitscheck, Ulrich, Schneider, Tanja

“…The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-positive pathogens, such as methicillin resistant Staphylococcus…”
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Characterization of serine hydroxymethyltransferase GlyA as a potential source of D-alanine in Chlamydia pneumoniae by De Benedetti, Stefania, Bühl, Henrike, Gaballah, Ahmed, Klöckner, Anna, Otten, Christian, Schneider, Tanja, Sahl, Hans-Georg, Henrichfreise, Beate

“…For intracellular Chlamydiaceae, there is no need to withstand osmotic challenges, and a functional cell wall has not been detected in these pathogens so far…”
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Co-Solvents as Stabilizing Agents during Heterologous Overexpression in Escherichia coli - Application to Chlamydial Penicillin-Binding Protein 6: e0122110 by Otten, Christian, Benedetti, Stefania De, Gaballah, Ahmed, Buehl, Henrike, Klockner, Anna, Brauner, Jarryd, Sahl, Hans-Georg, Henrichfreise, Beate

“…Heterologous overexpression of foreign proteins in Escherichia coli often leads to insoluble aggregates of misfolded inactive proteins, so-called inclusion…”
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