Search Results - "Klippstein, Rebecca"

Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies by Klippstein, Rebecca, MSc, Pozo, David, MSc, PhD

“…Abstract Dendritic cells (DCs) are potent antigen-presenting cells capable of initiating a primary immune response and possess the ability to activate T cells…”
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Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood–brain barrier in vitro and in vivo by Kafa, Houmam, Wang, Julie Tzu-Wen, Rubio, Noelia, Klippstein, Rebecca, Costa, Pedro M., Hassan, Hatem A.F.M., Sosabowski, Jane K., Bansal, Sukhvinder S., Preston, Jane E., Abbott, N. Joan, Al-Jamal, Khuloud T.

“…Brain glioblastoma and neurodegenerative diseases are still largely untreated due to the inability of most drugs to cross the blood–brain barrier (BBB)…”
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Engineering hepatitis B virus core particles for targeting HER2 receptors in vitro and in vivo by Suffian, Izzat Fahimuddin Bin Mohamed, Wang, Julie Tzu-Wen, Hodgins, Naomi O, Martin, Rebecca Klippstein, Garcia-Maya, Mitla, Brown, Paul, Nishimura, Yuya, Heidari, Hamed, Bals, Sara, Sosabowski, Jane, Ogino, Chiaki, Kondo, Akihiko, Al-Jamal, Khuloud T

“…Abstract Hepatitis B Virus core (HBc) particles have been studied for their potential as drug delivery vehicles for cancer therapy. HBc particles are hollow…”
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Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide by Rubio, Noelia, Mei, Kuo-Ching, Klippstein, Rebecca, Costa, Pedro M, Hodgins, Naomi, Wang, Julie Tzu-Wen, Festy, Frederic, Abbate, Vincenzo, Hider, Robert C, Chan, Ka Lung Andrew, Al-Jamal, Khuloud T

“…Polyethylene glycol-functionalized nanographene oxide (PEGylated n-GO) was synthesized from alkyne-modified n-GO, using solvent-free click-mechanochemistry,…”
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Kupffer Cell Isolation for Nanoparticle Toxicity Testing by Bourgognon, Maxime, Klippstein, Rebecca, Al-Jamal, Khuloud T.

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Vasoactive Intestinal Peptide (VIP) Nanoparticles for Diagnostics and for Controlled and Targeted Drug Delivery by Klippstein, Rebecca, Pozo, David

“…Neuropeptides are potentially valuable tools for clinical applications as they offer many distinct advantages over other bioactive molecules like proteins and…”
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Doxorubicin enhances curcumin’s cytotoxicity in human prostate cancer cells in vitro by enhancing its cellular uptake by Klippstein, Rebecca, Bansal, Sukhvinder S., Al-Jamal, Khuloud T.

“…[Display omitted] Doxorubicin (DOX) is a widely used drug in cancer treatment. Despite its popularity, it suffers from systemic side effects and susceptibility…”
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Passively Targeted Curcumin-Loaded PEGylated PLGA Nanocapsules for Colon Cancer Therapy In Vivo by Klippstein, Rebecca, Wang, Julie Tzu-Wen, El-Gogary, Riham I., Bai, Jie, Mustafa, Falisa, Rubio, Noelia, Bansal, Sukhvinder, Al-Jamal, Wafa T., Al-Jamal, Khuloud T.

“…Clinical applications of curcumin for the treatment of cancer and other chronic diseases have been mainly hindered by its short biological half‐life and poor…”
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Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo by El-Gogary, Riham I, Rubio, Noelia, Wang, Julie Tzu-Wen, Al-Jamal, Wafa’ T, Bourgognon, Maxime, Kafa, Houmam, Naeem, Muniba, Klippstein, Rebecca, Abbate, Vincenzo, Leroux, Frédéric, Bals, Sara, Van Tendeloo, Gustaaf, Kamel, Amany O, Awad, Gehanne A. S, Mortada, Nahed D, Al-Jamal, Khuloud T

“…In this work we describe the formulation and characterization of chemically modified polymeric nanocapsules incorporating the anticancer drug, quercetin, for…”
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Neutron-irradiated antibody-functionalised carbon nanocapsules for targeted cancer radiotherapy by Wang, Julie Tzu-Wen, Spinato, Cinzia, Klippstein, Rebecca, Costa, Pedro Miguel, Martincic, Markus, Pach, Elzbieta, Ruiz de Garibay, Aritz Perez, Ménard-Moyon, Cécilia, Feldman, Robert, Michel, Yves, Šefl, Martin, Kyriakou, Ioanna, Emfietzoglou, Dimitris, Saccavini, Jean-Claude, Ballesteros, Belén, Tobias, Gerard, Bianco, Alberto, Al-Jamal, Khuloud T.

“…Radiotherapy is a cancer treatment utilising high doses of ionizing radiation to destroy cancer cells. Our team has pioneered neutron activation of 152Sm,…”
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Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy by Hodgins, Naomi O., Al-Jamal, Wafa' T., Wang, Julie T.-W., Klippstein, Rebecca, Costa, Pedro M., Sosabowski, Jane K., Marshall, John F., Maher, John, Al-Jamal, Khuloud T.

“…The αvβ6 integrin receptor has been shown to be overexpressed on many types of cancer cells, resulting in a more pro-invasive and aggressive phenotype, this…”
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Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy by Ingallina, Cinzia, Costa, Pedro M, Ghirga, Francesca, Klippstein, Rebecca, Wang, Julie T, Berardozzi, Simone, Hodgins, Naomi, Infante, Paola, Pollard, Steven M, Botta, Bruno, Al-Jamal, Khuloud T

“…With the purpose of delivering high doses of glabrescione B (GlaB) to solid tumors after systemic administration, long-circulating GlaB-loaded oil-cored…”
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Kupffer Cell Isolation for Nanoparticle Toxicity Testing by Bourgognon, Maxime, Klippstein, Rebecca, Al-Jamal, Khuloud T

“…The large majority of in vitro nanotoxicological studies have used immortalized cell lines for their practicality. However, results from nanoparticle toxicity…”
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Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro by Ingallina, Cinzia, Costa, Pedro M, Ghirga, Francesca, Klippstein, Rebecca, Wang, Julie T, Berardozzi, Simone, Hodgins, Naomi, Infante, Paola, Pollard, Steven M, Botta, Bruno, Al-Jamal, Khuloud T

“…With the purpose of delivering high doses of glabrescione B (GlaB) to solid tumors after systemic administration, long-circulating GlaB-loaded oil-cored…”
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Design of antibody-functionalized carbon nanotubes filled with radioactivable metals towards a targeted anticancer therapy by Spinato, Cinzia, Perez Ruiz de Garibay, Aritz, Kierkowicz, Magdalena, Pach, Elzbieta, Martincic, Markus, Klippstein, Rebecca, Bourgognon, Maxime, Wang, Julie Tzu-Wen, Ménard-Moyon, Cécilia, Al-Jamal, Khuloud T, Ballesteros, Belén, Tobias, Gerard, Bianco, Alberto

“…In the present work we have devised the synthesis of a novel promising carbon nanotube carrier for the targeted delivery of radioactivity, through a…”
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Neutron Activated 153 Sm Sealed in Carbon Nanocapsules for in Vivo Imaging and Tumor Radiotherapy by Wang, Julie T-W, Klippstein, Rebecca, Martincic, Markus, Pach, Elzbieta, Feldman, Robert, Šefl, Martin, Michel, Yves, Asker, Daniel, Sosabowski, Jane K, Kalbac, Martin, Da Ros, Tatiana, Ménard-Moyon, Cécilia, Bianco, Alberto, Kyriakou, Ioanna, Emfietzoglou, Dimitris, Saccavini, Jean-Claude, Ballesteros, Belén, Al-Jamal, Khuloud T, Tobias, Gerard

“…Radiation therapy along with chemotherapy and surgery remain the main cancer treatments. Radiotherapy can be applied to patients externally (external beam…”
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Neutron Activated 153Sm Sealed in Carbon Nanocapsules for in Vivo Imaging and Tumor Radiotherapy by Wang, Julie T.-W, Klippstein, Rebecca, Martincic, Markus, Pach, Elzbieta, Feldman, Robert, Šefl, Martin, Michel, Yves, Asker, Daniel, Sosabowski, Jane K, Kalbac, Martin, Da Ros, Tatiana, Ménard-Moyon, Cécilia, Bianco, Alberto, Kyriakou, Ioanna, Emfietzoglou, Dimitris, Saccavini, Jean-Claude, Ballesteros, Belén, Al-Jamal, Khuloud T, Tobias, Gerard

“…Radiation therapy along with chemotherapy and surgery remain the main cancer treatments. Radiotherapy can be applied to patients externally (external beam…”
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Mixed micelles of lipoic acid-chitosan-poly(ethylene glycol) and distearoylphosphatidylethanolamine-poly(ethylene glycol) for tumor delivery by Elsaid, Zeeneh, Taylor, Kevin M.G., Puri, Sanyogitta, Eberlein, Cath A., Al-Jamal, Khuloud, Bai, Jie, Klippstein, Rebecca, Wang, Julie Tzu-Wen, Forbes, Ben, Chana, Jasminder, Somavarapu, Satyanarayana

“…Many chemotherapeutics suffer from poor aqueous solubility and tissue selectivity. Distearoylphosphatidylethanolamine-poly(ethylene glycol) (DSPE-PEG) micelles…”
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Cationic Liposome- Multi-Walled Carbon Nanotubes Hybrids for Dual siPLK1 and Doxorubicin Delivery In Vitro by Pereira, Sara, Lee, Jin, Rubio, Noelia, Hassan, Hatem A. F. M., Suffian, Izzat Bin Mohamed, Wang, Julie T. W., Klippstein, Rebecca, Ballesteros, Belén, Al-Jamal, Wafa’ T., Al-Jamal, Khuloud T.

“…Purpose To formulate f -MWNTs-cationic liposome hybrids for the simultaneous delivery of siPLK1 and doxorubicin to cancer cells. Method f -MWNTs-cationic…”
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Kupffer Cell Isolation for Nanoparticle Toxicity Testing by Bourgognon, Maxime, Klippstein, Rebecca, Al-Jamal, Khuloud T.

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