Search Results - "Klipping, Christine"
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Ovulation-Inhibiting Effects of Dienogest in a Randomized, Dose-Controlled Pharmacodynamic Trial of Healthy Women
Published in Journal of clinical pharmacology (01-11-2012)“…Dienogest offers pharmacological advantages for the effective treatment of endometriosis and for use in contraception and hormone replacement therapy. This…”
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Oral follicle-stimulating hormone agonist tested in healthy young women of reproductive age failed to demonstrate effect on follicular development but affected thyroid function
Published in Fertility and sterility (01-04-2016)“…Objective To assess the safety, pharmacokinetics, and pharmacodynamics of MK-8389. Design Double-blind, placebo-controlled, parallel-group, ascending dose…”
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Pharmacodynamic effects and plasma pharmacokinetics of single doses of cetrorelix acetate in healthy premenopausal women
Published in Fertility and sterility (01-02-2001)“…To investigate the pharmacodynamic effects and plasma pharmacokinetics of single subcutaneous doses of cetrorelix acetate in healthy premenopausal women. Phase…”
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4
Endocrine and metabolic effects of an oral contraceptive containing estetrol and drospirenone
Published in Contraception (Stoneham) (01-04-2021)“…To evaluate the effect on endocrine and metabolic parameters of a new combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP)…”
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Effects of an oral contraceptive containing estetrol and drospirenone on ovarian function
Published in Contraception (Stoneham) (01-06-2021)“…To evaluate the effects of estetrol 15 mg/drospirenone 3 mg on ovarian function. Single-center, randomized, open-label, parallel study in healthy young women…”
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Evaluation of the effect of a new oral contraceptive containing estetrol and drospirenone on hemostasis parameters
Published in Contraception (Stoneham) (01-12-2020)“…To assess the effect on hemostasis parameters of a new combined oral contraceptive (COC). In this randomized, single centre, open-label, exploratory study,…”
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Unintended drug exposure during pregnancy in clinical trials - a survey in early drug development
Published in International journal of clinical pharmacology and therapeutics (01-01-2021)“…To collect information on unintended drug exposure during pregnancy in early clinical drug development. Questionnaire mailed in autumn 2015 to members of human…”
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CHARACTERIZATION OF PITUITARY AND OVARIAN HORMONE CONCENTRATIONS DURING TREATMENT WITH RELUGOLIX COMBINATION THERAPY
Published in Fertility and sterility (01-09-2020)Get full text
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The effects on ovarian activity of delaying versus immediately restarting combined oral contraception after missing three pills and taking ulipristal acetate 30 mg
Published in Contraception (Stoneham) (01-09-2020)“…Among combined oral contraception (COC) users, to determine the effect on ovarian activity and ovulation of waiting five days before restarting COC, versus…”
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A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials
Published in Human reproduction (Oxford) (01-08-2017)“…Abstract STUDY QUESTION What are the differences and similarities of pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of the novel recombinant…”
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Suppression of ovarian activity with a drospirenone-containing oral contraceptive in a 24/4 regimen
Published in Contraception (Stoneham) (01-07-2008)“…Abstract Background This study was conducted to compare ovarian activity of an oral contraceptive containing drospirenone (drsp) 3 mg plus ethinylestradiol…”
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Reduced hemostatic effects with drospirenone-based oral contraceptives containing estetrol vs. ethinyl estradiol
Published in Contraception (Stoneham) (01-02-2017)“…Summary Objective The effects of estetrol (E4), a natural fetal estrogen, combined with drospirenone (DRSP) were evaluated on plasma levels of sex…”
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Ovulation inhibition with a new vaginal ring containing trimegestone
Published in Contraception (Stoneham) (01-10-2020)“…The primary objective was to determine the lowest trimegestone (TMG) dose, administered via a vaginal ring, that effectively inhibited ovulation…”
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Ovulation Inhibition With A New Vaginal Ring Containing Trimegestone
Published in Obstetrical & gynecological survey (01-02-2021)“…(Abstracted from Contraception 2020;102:237–242) Women receiving combined hormonal contraceptives (CHCs) are at increased risk of stroke, myocardial…”
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Effect on ovarian activity and ovulation inhibition of different oral dosages of levonorgestrel
Published in Contraception (Stoneham) (01-06-2022)“…To investigate the effect of different oral dosages of levonorgestrel (LNG) on ovarian activity and to identify the lowest dosage at which no ovulation…”
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Hormonal contraceptive use lowers female intrasexual competition in pair-bonded women
Published in Evolution and human behavior (01-07-2013)“…Abstract The purpose of this study was to test the influence of hormonal contraceptive use on levels of female intrasexual competition. Twenty-eight women…”
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A phase 2b multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of vaginal rings containing nomegestrol acetate or etonogestrel and 17β-estradiol in the treatment of women with primary dysmenorrhea
Published in Contraception (Stoneham) (01-02-2019)“…To evaluate the effect of investigational vaginal rings containing nomegestrol acetate (NOMAC) plus 17β-estradiol (E2) or etonogestrel (ENG) plus E2 in women…”
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Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive: An Open-Label, Randomized, Crossover Study of Estradiol Valerate/Dienogest versus Ethinylestradiol/Levonorgestrel
Published in Drugs in R&D (2011)“…Background: A novel estradiol-based combined oral contraceptive (COC) is currently available in many countries worldwide, including Europe and the US. Based on…”
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An Oral Contraceptive Containing Estetrol 15 MG and Drospirenone 3 MG Has Limited Effects on Endocrine and Metabolic Parameters
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Background: Most combined oral contraceptives (COCs) contain ethinylestradiol (EE), an estrogen component known to increase the risk of venous…”
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The Effect of Estetrol/Drospirenone on Ovarian Function Is Similar to a Well-Established Combined Oral Contraceptive: Results From a Phase 2 Study
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Background: Combined oral contraceptives (COCs) often contain ethinylestradiol (EE), an estrogen known to be associated with several side effects…”
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