Search Results - "Klintman, J."

PB2300: COMPLEMENT ACTIVATION NEGATIVELY AFFECTS THE PLATELET RESPONSE TO THROMBOPOIETIN RECEPTOR AGONISTS IN PATIENTS WITH IMMUNE THROMBOCYTOPENIA: A PROSPECTIVE COHORT STUDY by Åkesson, A., Bussel, J. B., Martin, M., Blom, A. M., Klintman, J., Ghanima, W., Zetterberg, E., Garabet, L.

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The prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures prior to FVIII inhibitor development by Reipert, B.M., Gangadharan, B., Hofbauer, C.J., Berg, V., Schweiger, H., Bowen, J., Blatny, J., Fijnvandraat, K., Mullins, E.S., Klintman, J., Male, C., McGuinn, C., Meeks, S.L., Radulescu, V.C., Ragni, M.V., Recht, M., Shapiro, A.D., Staber, J.M., Yaish, H.M., Santagostino, E., Brown, D.L.

“…Preventing factor VIII (FVIII) inhibitors following replacement therapies with FVIII products in patients with hemophilia A remains an unmet medical need…”
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Antibody formation and specificity in Bethesda-negative brother pairs with haemophilia A by Klintman, J., Hillarp, A., Donfield, S., Berntorp, E., Astermark, J.

“…Summary Antibodies directed towards non‐neutralizing epitopes on the factor VIII protein (FVIII) may be detected in patients with haemophilia A. We evaluated…”
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Thrombin generation in vitro in the presence of by-passing agents in siblings with severe haemophilia A by KLINTMAN, J., BERNTORP, E., ASTERMARK, J.

“…Previous data have shown an inter‐individual difference in the thrombin generating capacity in vitro as well as phenotypic bleeding pattern among patients with…”
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Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia by Klintman, Jenny, Appleby, Niamh, Stamatopoulos, Basile, Ridout, Katie, Eyre, Toby A., Robbe, Pauline, Pascua, Laura Lopez, Knight, Samantha J.L., Dreau, Helene, Cabes, Maite, Popitsch, Niko, Ehinger, Mats, Martín-Subero, Jose I., Campo, Elías, Månsson, Robert, Rossi, Davide, Taylor, Jenny C., Vavoulis, Dimitrios V., Schuh, Anna

“…The transformation of chronic lymphocytic leukemia (CLL) to high-grade B-cell lymphoma is known as Richter syndrome (RS), a rare event with dismal prognosis…”
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FFirst-line therapy in chronic lymphocytic leukemia: a Swedish nation-wide real-world study on 1053 consecutive patients treated between 2007 and 2013 by Sylvan, SE, Asklid, A, Johansson, H, Klintman, J, Bjellvi, J, Tolvgard, S, Kimby, E, Norin, S, Andersson, P-O, Karlsson, C

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First-line therapy in chronic lymphocytic leukemia: a Swedish nation-wide real-world study on 1053 consecutive patients treated between 2007 and 2013 by Sylvan, Sandra Eketorp, Asklid, Anna, Johansson, Hemming, Klintman, Jenny, Bjellvi, Jenny, Tolvgård, Staffan, Kimby, Eva, Norin, Stefan, Andersson, Per-Ola, Karlsson, Claes, Karlsson, Karin, Lauri, Birgitta, Mattsson, Mattias, Sandstedt, Anna Bergendahl, Strandberg, Maria, Österborg, Anders, Hansson, Lotta

“…The aim of this study was to investigate long-term outcome following first-line therapy in consecutive chronic lymphocytic leukemia (CLL) patients in a…”
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Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/ tal-1 gene by Orkin, Stuart H, Mikkola, Hanna K. A, Klintman, Jenny, Yang, Haidi, Hock, Hanno, Schlaeger, Thorsten M, Fujiwara, Yuko

“…The production of blood cells is sustained throughout the lifetime of an individual by haematopoietic stem cells (HSCs). Specification of HSCs from mesoderm…”
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Antibody formation and specificity in B ethesda‐negative brother pairs with haemophilia A by Klintman, J., Hillarp, A., Donfield, S., Berntorp, E., Astermark, J.

“…Summary Antibodies directed towards non‐neutralizing epitopes on the factor VIII protein ( FVIII ) may be detected in patients with haemophilia A . We…”
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Outcome of Patients with Chronic Lymphocytic Leukemia (CLL) Receiving First Line Therapy: A Swedish Nation-Wide Study on 1053 Consecutive Patients Treated between 2007 and 2013 by Eketorp Sylvan, Sandra, Asklid, Anna, Johansson, Hemming, Klintman, Jenny, Bjellvi, Jenny, Tolvgård, Staffan, Kimby, Eva, Norin, Stefan, Andersson, P-O, Karlsson, Claes, Karlsson, Karin, Lauri, Birgitta, Mattsson, Mattias, Sandstedt, Anna Bergendahl, Strandberg, Maria, Österborg, Anders, Hansson, Lotta

“…Background: The incidence of chronic lymphocytic leukemia (CLL) in Sweden is about 500/year. Previous US data suggest that region and type of…”
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PF376 DIFFERENTIAL GENOMIC AND TRANSCRIPTOMIC EVENTS ASSOCIATED WITH HIGH‐GRADE TRANSFORMATION OF CHRONIC LYMPHOCYTIC LEUKEMIA by Klintman, J., Stamatopoulos, B., Ridout, K., Eyre, T.A., Lopez Pascua, L., Appleby, N., Knight, S., Dreau, H., Ehinger, M., Martín‐Subero, J.I., Campo, E., Mansson, R., Rossi, D., Taylor, J., Vavoulis, D.V., Schuh, A.

“…Background: The high‐grade transformation of chronic lymphocytic leukemia (CLL), also called Richter's Syndrome (RS), carries a dismal prognosis. RS shares the…”
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Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-β signaling in vivo by Larsson, Jonas, Blank, Ulrika, Klintman, Jenny, Magnusson, Mattias, Karlsson, Stefan

“…Maintained quiescence of hematopoietic stem cells (HSCs) is of critical importance to prevent premature exhaustion of the stem cell pool under conditions of…”
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