Search Results - "Klinov, Dmitry V"
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Stable Enzymatic Nanoparticles from Nucleases, Proteases, Lipase and Antioxidant Proteins with Substrate-Binding and Catalytic Properties
Published in International journal of molecular sciences (03-02-2023)“…Limited membrane permeability and biodegradation hamper the intracellular delivery of the free natural or recombinant enzymes necessary for compensatory…”
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AFM visualization at a single-molecule level of denaturated states of proteins on graphite
Published in Colloids and surfaces, B, Biointerfaces (01-10-2016)“…[Display omitted] High resolution AFM distinguishes conformational states of single adsorbed proteins.Graphite induced protein denaturation is visualized at…”
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3
Polymorphism of G4 associates: from stacks to wires via interlocks
Published in Nucleic acids research (28-09-2018)“…Abstract We examined the assembly of DNA G-quadruplexes (G4s) into higher-order structures using atomic force microscopy, optical and electrophoretic methods,…”
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Features of DNA-Montmorillonite Binding Visualized by Atomic Force Microscopy
Published in International journal of molecular sciences (06-06-2023)“…In the present work, complexes of DNA with nano-clay montmorillonite (Mt) were investigated by means of atomic force microscopy (AFM) under various conditions…”
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Time-Lapse Single-Biomolecule Atomic Force Microscopy Investigation on Modified Graphite in Solution
Published in Langmuir (26-09-2017)“…Atomic force microscopy (AFM) of biomolecular processes at the single-molecule level can provide unique information for understanding molecular function. In…”
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Activation of Neutrophils by Mucin–Vaterite Microparticles
Published in International journal of molecular sciences (13-09-2022)“…Nano- and microparticles enter the body through the respiratory airways and the digestive system, or form as biominerals in the gall bladder, salivary glands,…”
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Incorporation of Pectin into Vaterite Microparticles Prevented Effects of Adsorbed Mucin on Neutrophil Activation
Published in International journal of molecular sciences (01-11-2023)“…The application of vaterite microparticles for mucosal delivery depends on their interaction with mucin and immune cells. As we have shown previously, the…”
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Targeting of Silver Cations, Silver-Cystine Complexes, Ag Nanoclusters, and Nanoparticles towards SARS-CoV-2 RNA and Recombinant Virion Proteins
Published in Viruses (26-04-2022)“…: Nanosilver possesses antiviral, antibacterial, anti-inflammatory, anti-angiogenesis, antiplatelet, and anticancer properties. The development of…”
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Deep Learning for Cell Migration in Nonwoven Materials and Evaluating Gene Transfer Effects following AAV6-ND4 Transduction
Published in Polymers (01-05-2024)“…Studying cell settlement in the three-dimensional structure of synthetic biomaterials over time is of great interest in research and clinical translation for…”
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Neutrophil Activation by Mineral Microparticles Coated with Methylglyoxal-Glycated Albumin
Published in International journal of molecular sciences (16-07-2022)“…Hyperglycemia-induced protein glycation and formation of advanced glycation end-products (AGEs) plays an important role in the pathogenesis of diabetic…”
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11
Can Dissipative Properties of Single Molecules Be Extracted from a Force Spectroscopy Experiment?
Published in Biophysical journal (20-09-2016)“…We performed dynamic force spectroscopy of single dextran and titin I27 molecules using small-amplitude and low-frequency (40–240 Hz) dithering of an atomic…”
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12
Influence of natural polysaccharides on the morphology and properties of hybrid vaterite microcrystals
Published in Heliyon (15-07-2024)“…Co-precipitation of biopolymers into calcium carbonate crystals changes their physicochemical and biological properties. This work studies hybrid microcrystals…”
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13
Adsorbed plasma proteins modulate the effects of single-walled carbon nanotubes on neutrophils in blood
Published in Nanomedicine (01-08-2016)“…Abstract Proteins adsorbed on a surface may affect the interaction of this surface with cells. Here, we studied the binding of human serum albumin (HSA),…”
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14
Observation of single-stranded DNA on mica and highly oriented pyrolytic graphite by atomic force microscopy
Published in FEBS letters (16-10-2006)“…Atomic force microscopy was used to image single-stranded DNA (ssDNA) adsorbed on mica modified by Mg 2+, by 3-aminopropyltriethoxysilane or on modified highly…”
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The Dynamics of Mycoplasma gallisepticum Nucleoid Structure at the Exponential and Stationary Growth Phases
Published in Frontiers in microbiology (18-11-2021)“…The structure and dynamics of bacterial nucleoids play important roles in regulating gene expression. Bacteria of class Mollicutes and, in particular,…”
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Application of vasoactive and matrix-modifying drugs can improve polyplex delivery to tumors upon intravenous administration
Published in Journal of controlled release (28-06-2016)“…Low efficacy of cationic polymer-based formulations (polyplexes) for systemic gene delivery to tumors remains the crucial concern for their clinical…”
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Anomalous Laterally Stressed Kinetically Trapped DNA Surface Conformations
Published in Nano-micro letters (01-12-2021)“…Highlights DNA kinking is inevitable for the highly anisotropic 1D–1D electrostatic interaction with the one-dimensionally periodically charged surface. The…”
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Wall Thickness of Industrial Multi-Walled Carbon Nanotubes Is Not a Crucial Factor for Their Degradation by Sodium Hypochlorite
Published in Nanomaterials (Basel, Switzerland) (12-09-2018)“…The propensity of multi-walled carbon nanotubes (MWCNTs) for biodegradation is important for their safe use in medical and technological applications. Here, we…”
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Single-molecule AFM study of hyaluronic acid softening in electrolyte solutions
Published in Carbohydrate polymers (01-03-2023)“…Investigation of hyaluronic acid (HA) morphology and mechanical properties at a single-molecule level is important for the development of HA based…”
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Spatial organization of Dps and DNA–Dps complexes
Published in Journal of molecular biology (14-05-2021)“…[Display omitted] •Dps protects bacterial genome from harmful effects by co-crystallization with DNA.•DNA does not wrap Dps molecules in DNA–Dps complexes in…”
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