Search Results - "Klinger, J. R."

Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at 3 months: multicenter double‐blind, placebo‐controlled randomized trial by Kline, J. A., Nordenholz, K. E., Courtney, D. M., Kabrhel, C., Jones, A. E., Rondina, M. T., Diercks, D. B., Klinger, J. R., Hernandez, J.

“…Summary Background Acute pulmonary embolism (PE) can worsen quality of life due to persistent dyspnea or exercise intolerance. Objective Test if tenecteplase…”
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Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats by Karamsetty, M R, Klinger, J R, Hill, N S

“…Phytoestrogens derived from soybeans reverse endothelial dysfunction in a number of animal models of systemic vascular disease. Based on these studies, we…”
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Low-cycle fatigue of unidirectional composites:: Bi-linear S– N curves by Harik, V.M., Klinger, J.R., Bogetti, T.A.

“…Low-cycle fatigue (LCF) behavior of polymer matrix composites (PMCs) is investigated in an experimental study of unidirectional glass/epoxy composites…”
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Echocardiographic Pulmonary Hypertension Predicts Post-transplantation Renal Allograft Failure by Foderaro, A.E., Baird, G.L., Bazargan-Lari, A., Morrissey, P.E., Gohh, R.Y., Poppas, A., Klinger, J.R., Ventetuolo, C.E.

“…Pulmonary hypertension in the setting of renal transplantation has been associated with early allograft dysfunction and increased mortality, but this…”
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Evidence for the role of p38 MAP kinase in hypoxia-induced pulmonary vasoconstriction by Karamsetty, M R, Klinger, J R, Hill, N S

“…Mitogen-activated protein (MAP) kinases regulate smooth muscle cell contraction. Hypoxia contracts pulmonary arteries by mechanisms that are incompletely…”
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EDHF contributes to strain-related differences in pulmonary arterial relaxation in rats by Karamsetty, M R, Nakashima, J M, Ou, L, Klinger, J R, Hill, N S

“…Pulmonary arteries from the Madison (M) strain relax more in response to acetylcholine (ACh) than those from the Hilltop (H) strain of Sprague-Dawley rats. We…”
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Right ventricular dysfunction in chronic obstructive pulmonary disease. Evaluation and management by Klinger, J R, Hill, N S

“…Cor pulmonale is an important consequence of COPD. Although the incidence is not precisely known, it is seen more frequently in patients with hypoxemia, CO2…”
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Brain natriuretic peptide: possible role in the modulation of hypoxic pulmonary hypertension by Hill, N S, Klinger, J R, Warburton, R R, Pietras, L, Wrenn, D S

“…To test the hypothesis that brain natriuretic peptide (BNP) plays a role similar to that of atrial natriuretic peptide (ANP) in modulating pulmonary vascular…”
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Downregulation of pulmonary atrial natriuretic peptide receptors in rats exposed to chronic hypoxia by Klinger, J R, Arnal, F, Warburton, R R, Ou, L C, Hill, N S

“…We hypothesized that a downregulation in pulmonary atrial natriuretic peptide (ANP) receptors helps raise plasma ANP levels during chronic hypoxia. We measured…”
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Cardiopulmonary responses to chronic hypoxia in transgenic mice that overexpress ANP by Klinger, J R, Petit, R D, Curtin, L A, Warburton, R R, Wrenn, D S, Steinhelper, M E, Field, L J, Hill, N S

“…Elevated plasma atrial natriuretic peptide (ANP) levels have been shown to blunt pulmonary hemodynamic responses to chronic hypoxia, but whether elevated…”
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Atrial natriuretic peptide accounts for increased cGMP in hypoxia-induced hypertensive rat lungs by Muramatsu, M, Tyler, R C, Gutkowska, J, Klinger, J R, Hill, N S, Rodman, D M, McMurtry, I F

“…Perfusate levels of nitric oxide (NO)-containing compounds and guanosine 3',5'-cyclic monophosphate (cGMP) are increased in hypoxia-induced hypertensive rat…”
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Pulmonary complications from alveolar accumulation of carbonaceous material in a cocaine smoker by Klinger, J R, Bensadoun, E, Corrao, W M

“…A 27-year-old woman presented with cough, fever, and pulmonary infiltrates after heavy cocaine smoking. Large amounts of carbonaceous material and…”
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Multiple cases of life-threatening adenovirus pneumonia in a mental health care center by KLINGER, J. R, SANCHEZ, M. P, CURTIN, L. A, DURKIN, M, MATYAS, B

“…Eighteen cases of pneumonia developed during an outbreak of adenovirus infection in a chronic psychiatric care facility. The six patients most severely…”
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Atrial natriuretic peptide expression in rats with different pulmonary hypertensive responses to hypoxia by Klinger, J R, Wrenn, D S, Warburton, R R, Pietras, L, Ou, L C, Hill, N S

“…Mechanisms that regulate atrial natriuretic peptide (ANP) expression during hypoxia are not well defined. We hypothesized that plasma immunoreactive ANP…”
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Neutral endopeptidase inhibition attenuates development of hypoxic pulmonary hypertension in rats by Klinger, J R, Petit, R D, Warburton, R R, Wrenn, D S, Arnal, F, Hill, N S

“…Neutral endopeptidase (NEP) inhibition is thought to blunt hypoxic pulmonary hypertension by reducing atrial natriuretic peptide (ANP) metabolism, but this…”
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Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats by Hill, Nicholas S, Warburton, Rod R, Pietras, Linda, Klinger, James R

“…Nicholas S. Hill, Rod R. Warburton, Linda Pietras, and James R. Klinger Division of Pulmonary, Sleep Disorders, and Critical Care Medicine, Rhode Island…”
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C-receptor ligand blocks pulmonary clearance of atrial natriuretic peptide in isolated rat lungs by Klinger, J R, Moalli, R, Warburton, R R, Wrenn, D S, Hill, N S

“…Pulmonary clearance of atrial natriuretic peptide (ANP) was measured by indicator dilution technique in isolated perfused rat lungs with and without ANP…”
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Brain natriuretic peptide inhibits hypoxic pulmonary hypertension in rats by Klinger, James R, Warburton, Rod R, Pietras, Linda, Hill, Nicholas S

“…Division of Pulmonary and Critical Care Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903 Brain…”
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Sex and haemodynamics in pulmonary arterial hypertension by VENTETUOLO, Corey E, PRAESTGAARD, Amy, PALEVSKY, Harold I, KLINGER, James R, HALPERN, Scott D, KAWUT, Steven M

“…Female sex is a risk factor for pulmonary arterial hypertension (PAH), yet females have better survival than males. We sought to determine if sex was…”
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Hemodynamics and positive end-expiratory pressure in critically ill patients by Klinger, J R

“…This article examines the factors that affect the transmission of airway pressures to intrathoracic structures. The effects of positive end-expiratory pressure…”
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