Search Results - "Kling, Mitchel"

Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias by Yarchoan, Mark, Xie, Sharon X., Kling, Mitchel A., Toledo, Jon B., Wolk, David A., Lee, Edward B., Van Deerlin, Vivianna, Lee, Virginia M.-Y., Trojanowski, John Q., Arnold, Steven E.

“…A growing body of evidence demonstrates an association between vascular risk factors and Alzheimer’s disease. This study investigated the frequency and…”
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Digital assessment of cognition in neurodegenerative disease: a data driven approach leveraging artificial intelligence by Libon, David J, Swenson, Rod, Price, Catherine C, Lamar, Melissa, Cosentino, Stephanie, Bezdicek, Ondrej, Kling, Mitchel A, Tobyne, Sean, Jannati, Ali, Banks, Russell, Pascual-Leone, Alvaro

“…A rapid and reliable neuropsychological protocol is essential for the efficient assessment of neurocognitive constructs related to emergent neurodegenerative…”
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A cross-sectional study of untreated depression and anxiety in cutaneous lupus erythematosus and dermatomyositis by Achtman, Jordan, BA, Kling, Mitchel A., MD, Feng, Rui, PhD, Okawa, Joyce, RN, Werth, Victoria P., MD

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Vascular disease and dementias: Paradigm shifts to drive research in new directions by Kling, Mitchel A, Trojanowski, John Q, Wolk, David A, Lee, Virginia M.Y, Arnold, Steven E

“…Abstract Vascular disease was once considered the principal cause of aging-related dementia. More recently, however, research emphasis has shifted to studies…”
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Subjective Memory Complaints, Cognitive Performance, and Psychological Factors in Healthy Older Adults by Steinberg, Susanne I., Negash, Selamawit, Sammel, Mary D., Bogner, Hillary, Harel, Brian T., Livney, Melissa G., McCoubrey, Hannah, Wolk, David A., Kling, Mitchel A., Arnold, Steven E.

“…Objective: To determine whether subjective memory complaints (SMCs) are associated with performance on objective cognitive measures and psychological factors…”
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Elevated Cerebrospinal Fluid Lactate Concentrations in Patients with Bipolar Disorder and Schizophrenia: Implications for the Mitochondrial Dysfunction Hypothesis by Regenold, William T, Phatak, Pornima, Marano, Christopher M, Sassan, Amritpal, Conley, Robert R, Kling, Mitchel A

“…Background Evidence is accumulating that mitochondrial dysfunction is involved in the pathophysiology of bipolar disorder and schizophrenia. Cerebrospinal…”
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Ecological momentary assessment of daily affect, stress, and nightmare reports among combat-exposed veterans by Miller, Katherine E., Boland, Elaine M., Barilla, Holly, Ross, Richard J., Kling, Mitchel A., Bhatnagar, Seema, Gehrman, Philip R.

“…Research primarily in civilian samples supports bidirectional relations between daytime factors and trauma-related nightmare (TRN) reports. This study tested…”
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Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease by Yarchoan, Mark, Louneva, Natalia, Xie, Sharon X, Swenson, Frank J, Hu, William, Soares, Holly, Trojanowski, John Q, Lee, Virginia M.-Y, Kling, Mitchel A, Shaw, Leslie M, Chen-Plotkin, Alice, Wolk, David A, Arnold, Steven E

“…Abstract C-reactive protein (CRP) participates in the systemic response to inflammation. Previous studies report inconsistent findings regarding the…”
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Effects of 12 Months of Vagus Nerve Stimulation in Treatment-Resistant Depression: A Naturalistic Study by Rush, A. John, Sackeim, Harold A., Marangell, Lauren B., George, Mark S., Brannan, Stephen K., Davis, Sonia M., Lavori, Phil, Howland, Robert, Kling, Mitchel A., Rittberg, Barry, Carpenter, Linda, Ninan, Philip, Moreno, Francisco, Schwartz, Thomas, Conway, Charles, Burke, Michael, Barry, John J.

“…The need for effective, long-term treatment for recurrent or chronic, treatment-resistant depression is well established. This naturalistic follow-up describes…”
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ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease by Ko, Yi-An, Billheimer, Jeffrey T, Lyssenko, Nicholas N, Kueider-Paisley, Alexandra, Wolk, David A, Arnold, Steven E, Leung, Yuk Yee, Shaw, Leslie M, Trojanowski, John Q, Kaddurah-Daouk, Rima F, Kling, Mitchel A, Rader, Daniel J

“…Alzheimer's disease (AD) shares risk factors with cardiovascular disease (CVD) and dysregulated cholesterol metabolism is a mechanism common to both diseases…”
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Treatment Outcomes in Depression: Comparison of Remote Treatment Through Telepsychiatry to In-Person Treatment by Ruskin, Paul E., Silver-Aylaian, Michele, Kling, Mitchel A., Reed, Susan A., Bradham, Douglas D., Hebel, J. Richard, Barrett, David, Knowles, Frederick, Hauser, Peter

“…OBJECTIVE: Telepsychiatry is an increasingly common method of providing psychiatric care, but randomized trials of telepsychiatric treatment compared to…”
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Targeted Plasmalogen Supplementation: Effects on Blood Plasmalogens, Oxidative Stress Biomarkers, Cognition, and Mobility in Cognitively Impaired Persons by Goodenowe, Dayan B., Haroon, Jonathan, Kling, Mitchel A., Zielinski, Margaret, Mahdavi, Kennedy, Habelhah, Barshen, Shtilkind, Leah, Jordan, Sheldon

“…Plasmalogens are a specific type of glycerophospholipid found in especially high levels in neuronal membranes. Decreased blood and brain levels of…”
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Cerebrospinal fluid evidence of increased extra-mitochondrial glucose metabolism implicates mitochondrial dysfunction in multiple sclerosis disease progression by Regenold, William T, Phatak, Pornima, Makley, Michael J, Stone, Roger D, Kling, Mitchel A

“…Abstract In contrast to relapse, the mechanisms of multiple sclerosis (MS) disease progression are less understood and appear not to be exclusively…”
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Vagus Nerve Stimulation for Treatment-Resistant Depression: A Randomized, Controlled Acute Phase Trial by Rush, A. John, Marangell, Lauren B., Sackeim, Harold A., George, Mark S., Brannan, Stephen K., Davis, Sonia M., Howland, Robert, Kling, Mitchel A., Rittberg, Barry R., Burke, William J., Rapaport, Mark H., Zajecka, John, Nierenberg, Andrew A., Husain, Mustafa M., Ginsberg, David, Cooke, Robert G.

“…Vagus nerve stimulation (VNS) alters both concentrations of neurotransmitters or their metabolites and functional activity of central nervous system regions…”
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Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease by Cipollari, Eleonora, Szapary, Hannah J, Picataggi, Antonino, Billheimer, Jeffrey T, Lyssenko, Catherine A, Ying, Gui-Shuang, Shaw, Leslie M, Kling, Mitchel A, Kaddurah-Daouk, Rima, Rader, Daniel J, Praticò, Domenico, Lyssenko, Nicholas N

“…Basic research has implicated intracellular cholesterol in neurons, microglia, and astrocytes in the pathogenesis of Alzheimer's disease (AD), but there is…”
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Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau by Kling, Mitchel A., Goodenowe, Dayan B., Senanayake, Vijitha, MahmoudianDehkordi, Siamak, Arnold, Matthias, Massaro, Tyler J., Baillie, Rebecca, Han, Xianlin, Leung, Yuk‐Yee, Saykin, Andrew J., Nho, Kwangsik, Kueider‐Paisley, Alexandra, Tenenbaum, Jessica D., Wang, Li‐San, Shaw, Leslie M., Trojanowski, John Q., Kaddurah‐Daouk, Rima F.

“…Introduction Altered lipid metabolism is implicated in Alzheimer's disease (AD), but the mechanisms remain obscure. Aging‐related declines in circulating…”
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A One-Year Comparison of Vagus Nerve Stimulation with Treatment as Usual for Treatment-Resistant Depression by George, Mark S., Rush, A. John, Marangell, Lauren B., Sackeim, Harold A., Brannan, Stephen K., Davis, Sonia M., Howland, Robert, Kling, Mitchel A., Moreno, Francisco, Rittberg, Barry, Dunner, David, Schwartz, Thomas, Carpenter, Linda, Burke, Michael, Ninan, Philip, Goodnick, Paul

“…Previous reports have described the effects of vagus nerve stimulation plus treatment as usual (VNS+TAU) during open trials of patients with…”
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Major Depression Is Associated with Significant Diurnal Elevations in Plasma Interleukin-6 Levels, a Shift of Its Circadian Rhythm, and Loss of Physiological Complexity in Its Secretion: Clinical Implications by Alesci, Salvatore, Martinez, Pedro E., Kelkar, Sujata, Ilias, Ioannis, Ronsaville, Donna S., Listwak, Samuel J., Ayala, Alejandro R., Licinio, Julio, Gold, Herman K., Kling, Mitchel A., Chrousos, George P., Gold, Philip W.

“…Background: Major depressive disorder (MDD) is associated with increased risk for premature coronary heart disease and bone loss. Single time measurements of…”
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The association of polysomnographic sleep on posttraumatic stress disorder symptom clusters in trauma-exposed civilians and veterans by Brownlow, Janeese A, Miller, Katherine E, Ross, Richard J, Barilla, Holly, Kling, Mitchel A, Bhatnagar, Seema, Mellman, Thomas A, Gehrman, Philip R

“…Abstract Study Objectives Self-reported sleep disturbance has been established as a risk factor and predictor for posttraumatic stress disorder (PTSD);…”
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Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges by O'Bryant, Sid E, Lista, Simone, Rissman, Robert A, Edwards, Melissa, Zhang, Fan, Hall, James, Zetterberg, Henrik, Lovestone, Simon, Gupta, Veer, Graff-Radford, Neill, Martins, Ralph, Jeromin, Andreas, Waring, Stephen, Oh, Esther, Kling, Mitchel, Baker, Laura D, Hampel, Harald

“…Abstract Introduction This study investigated the comparability of potential Alzheimer's disease (AD) biomarkers across blood fractions and assay platforms…”
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