Search Results - "Kline, R P"
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1
Rapid in Vivo Monitoring of Chemotherapeutic Response Using Weighted Sodium Magnetic Resonance Imaging
Published in Clinical cancer research (01-06-2000)“…A novel pulse sequence strategy uses sodium magnetic resonance imaging to monitor the response to chemotherapy of mouse xenograft tumors propagated from human…”
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2
Endothelin-Dependent Actions in Cultured At-1 Cardiac Myocytes: The Role of the epsilon Isoform of Protein Kinase C
Published in Circulation research (01-04-1996)“…The consequences of endothelin receptor activation were examined in atrial tumor myocytes derived from transgenic mice (AT-1 cells). Endothelin-1 (endothelin)…”
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3
Gating of Isk expressed in xenopus oocytes depends on the amount of mRNA injected
Published in The Journal of general physiology (01-07-1994)“…IsK is a K+ channel of the delayed rectifier type widely distributed throughout both excitable and nonexcitable cells. Its structure is different from other…”
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4
Effects of α-Adrenergic Stimulation on Intracellular Sodium Activity and Automaticity in Canine Purkinje Fibers
Published in Circulation research (01-02-1990)“…Approximately 60% of adult canine Purkinje fibers respond to α1-adrenergic stimulation with a decrease in automaticity. Recent studies of disaggregated…”
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5
Statistical properties predicted by the ball and chain model of channel inactivation
Published in Biophysical journal (01-12-1992)“…It has been proposed that part of a voltage gated channel is a tethered ball and that inactivation occurs when this wandering ball binds to a site in the…”
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6
Potassium efflux in heart muscle during activity: extracellular accumulation and its implications
Published in The Journal of physiology (01-07-1978)“…1. Extracellular K+ activity and transmembrane potential were simultaneously monitored with a K+-selective micro-electrode placed in the extracellular space…”
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7
Expression and characterization of a canine hippocampal inwardly rectifying K+ current in Xenopus oocytes
Published in The Journal of physiology (01-11-1992)“…1. An inwardly rectifying potassium current expressed in Xenopus laevis oocytes injected with canine hippocampal poly(A)+ RNA was investigated with the…”
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8
Zatebradine Slows Ectopic Ventricular Rhythms in Canine Heart 24 Hours After Coronary Artery Ligation
Published in Journal of cardiovascular pharmacology (01-05-1997)“…Arrhythmias occur 24 h after occlusion of the left anterior descending (LAD) coronary artery in the canine heart and have been attributed to the abnormal…”
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9
Generation of b-Wave Currents in the Skate Retina
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1978)“…Potassium kinetics within the skate retina were monitored extracellularly with K+-selective electrodes. Two sources of K+ efflux were detected in response to…”
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10
Intracellular K+ Activity, Intracellular Na+ Activity and Maximum Diastolic Potential of Canine Subendocardial Purkinje Cells From One-Day-Old Infarcts
Published in Circulation research (01-01-1987)“…The basis for the reduced maximum diastolic potential of canine cardiac subendocardial Purkinje fibers surviving one day after extensive transmural infarction…”
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11
Triggered activity in atrial fibres of canine coronary sinus: role of extracellular potassium accumulation and depletion
Published in The Journal of physiology (01-02-1987)“…1. Bursts of triggered activity can be induced in atrial fibres of the canine coronary sinus exposed to catecholamines. During a triggered burst there is an…”
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12
Light-induced potassium fluxes in the skate retina
Published in Neuroscience (01-01-1985)“…Changes in the extracellular concentration of potassium [K+]0 in response to photic stimulation were studied in the skate retina with the aid of ion-selective…”
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13
Intracellular pH of Canine Subendocardial Purkinje Cells Surviving in 1-Day-Old Myocardial Infarcts
Published in Circulation research (01-09-1989)“…A large reduction of intracellular potassium activity in depolarized subendocardial Purkinje fibers 24 hours after coronary artery ligation is accompanied by a…”
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14
Extracellular calcium ion depletion in frog cardiac ventricular muscle
Published in Biophysical journal (01-07-1985)“…The extracellular free [Ca++] in frog ventricular muscle strips was monitored using single-barrel calcium ion-selective microelectrodes. During trains of…”
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15
Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture
Published in The American journal of physiology (01-09-1999)“…Excessive nitric oxide (NO) production within the heart is implicated in the pathogenesis of myocyte death, but the mechanism whereby NO kills cardiac myocytes…”
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16
The Effect of Brief Vagal Stimulation on the Isolated Rabbit Sinus Node
Published in Circulation research (01-01-1979)“…We developed an isolated rabbit atrial preparation which responds consistently and reproducibly to brief, aubmaximal stimulation of the autonomic nerves…”
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17
Extracellular [K+] fluctuations in voltage-clamped canine cardiac Purkinje fibers
Published in Biophysical journal (01-11-1984)“…Membrane currents and extracellular [K+] were measured in canine Purkinje strands during voltage-clamp steps to plateau or diastolic potentials. Extracellular…”
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18
Time Course of Changes in Intracellular K+, Na+, and pH of Subendocardial Purkinje Cells During the First 24 Hours After Coronary Occlusion
Published in Circulation research (01-03-1992)“…We investigated the basis for the alterations in the intracellular potassium and sodium activity occurring in subendocardial Purkinje fibers surviving in…”
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19
Interaction of intracellular ion buffering with transmembrane-coupled ion transport
Published in The Journal of general physiology (01-03-1990)“…The role of the Na/Ca exchanger in the control of cellular excitability and tension development is a subject of current interest in cardiac physiology. It has…”
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20
Voltage-clamp studies on the canine Purkinje strand
Published in Proceedings of the Royal Society of London. Series B, Biological sciences (22-01-1983)“…Purkinje strands were excised from the left and right ventricles of adult mongrel dogs and cut to lengths of less than 2.0 mm in order to apply the…”
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