Search Results - "Klimovich, Polina"

New Frontiers in Peripheral Nerve Regeneration: Concerns and Remedies by Klimovich, Polina, Rubina, Kseniya, Sysoeva, Veronika, Semina, Ekaterina

“…Topical advances in studying molecular and cellular mechanisms responsible for regeneration in the peripheral nervous system have highlighted the ability of…”
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Urokinase System in Pathogenesis of Pulmonary Fibrosis: A Hidden Threat of COVID-19 by Shmakova, Anna A, Popov, Vladimir S, Romanov, Iliya P, Khabibullin, Nikita R, Sabitova, Nailya R, Karpukhina, Anna A, Kozhevnikova, Yana A, Kurilina, Ella V, Tsokolaeva, Zoya I, Klimovich, Polina S, Rubina, Kseniya A, Vassetzky, Yegor S, Semina, Ekaterina V

“…Pulmonary fibrosis is a common and threatening post-COVID-19 complication with poorly resolved molecular mechanisms and no established treatment. The…”
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Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma by Semina, Ekaterina V., Rubina, Kseniya A., Shmakova, Anna A., Rysenkova, Karina D., Klimovich, Polina S., Aleksanrushkina, Natalya A., Sysoeva, Veronika Y., Karagyaur, Maxim N., Tkachuk, Vsevolod A.

“…The urokinase system is involved in a variety of physiological processes, such as fibrinolysis, matrix remodeling, wound healing, and regeneration. Upon…”
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T-Cadherin Deficiency Is Associated with Increased Blood Pressure after Physical Activity by Popov, Vladimir S, Brodsky, Ilya B, Balatskaya, Maria N, Balatskiy, Alexander V, Ozhimalov, Ilia D, Kulebyakina, Maria A, Semina, Ekaterina V, Arbatskiy, Mikhail S, Isakova, Viktoria S, Klimovich, Polina S, Sysoeva, Veronika Y, Kalinina, Natalia I, Tkachuk, Vsevolod A, Rubina, Kseniya A

“…T-cadherin is a regulator of blood vessel remodeling and angiogenesis, involved in adiponectin-mediated protective effects in the cardiovascular system and in…”
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Mesenchymal stem/stromal cells alleviate early‐stage pulmonary fibrosis in a uPAR‐dependent manner by Efimenko, Anastasia Yu, Shmakova, Anna A., Popov, Vladimir S., Basalova, Natalia A., Vigovskiy, Maxim A., Grigorieva, Olga A., Sysoeva, Veronika Yu, Klimovich, Polina S., Khabibullin, Nikita R., Tkachuk, Vsevolod A., Rubina, Kseniya A., Semina, Ekaterina V.

“…Pulmonary fibrosis, a debilitating lung disorder characterised by excessive fibrous tissue accumulation in lung parenchyma, compromises respiratory function…”
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Novel missense variants in brain morphogenic genes associated with depression and schizophrenia by Karagyaur, Maxim, Primak, Alexandra, Bozov, Kirill, Sheleg, Dmitriy, Arbatsky, Mikhail, Dzhauari, Stalik, Illarionova, Maria, Semina, Ekaterina, Samokhodskaya, Larisa, Klimovich, Polina, Velichko, Arkadiy, Drach, Mikhail, Sotskaya, Ekaterina, Popov, Vladimir, Rubina, Kseniya, Parfenenko, Mariia, Makus, Julia, Tsygankov, Boris, Tkachuk, Vsevolod, Neyfeld, Elena

“…Impaired function of brain morphogenic genes is considered one of the predisposing factors for the manifestation of psychiatric and cognitive disorders, such…”
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Early Induction of Neurotrophin Receptor and miRNA Genes in Mouse Brain after Pentilenetetrazole-Induced Neuronal Activity by Shmakova, Anna A., Rysenkova, Karina D., Ivashkina, Olga I., Gruzdeva, Anna M., Klimovich, Polina S., Popov, Vladimir S., Rubina, Kseniya A., Anokhin, Konstantin V., Tkachuk, Vsevolod A., Semina, Ekaterina V.

“…Neurotrophin receptors regulate neuronal survival and network formation, as well as synaptic plasticity in the brain via interaction with their ligands. Here,…”
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Three-Dimensional Model of Dorsal Root Ganglion Explant as a Method of Studying Neurotrophic Factors in Regenerative Medicine by Klimovich, Polina, Rubina, Kseniya, Sysoeva, Veronika, Semina, Ekaterina

“…Neurotrophiс factors play a key role in the development, differentiation, and survival of neurons and nerve regeneration. In the present study, we evaluated…”
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Urokinase Receptor uPAR Downregulation in Neuroblastoma Leads to Dormancy, Chemoresistance and Metastasis by Shmakova, Anna A, Klimovich, Polina S, Rysenkova, Karina D, Popov, Vladimir S, Gorbunova, Anna S, Karpukhina, Anna A, Karagyaur, Maxim N, Rubina, Kseniya A, Tkachuk, Vsevolod A, Semina, Ekaterina V

“…uPAR is a membrane receptor that binds extracellular protease urokinase, contributes to matrix remodeling and plays a crucial role in cellular adhesion,…”
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Identification of a Novel Small RNA Encoded in the Mouse Urokinase Receptor uPAR Gene (Plaur) and Its Molecular Target Mef2d by Rysenkova, Karina D., Troyanovskiy, Konstantin E., Klimovich, Polina S., Bulyakova, Taisiya R., Shelomentseva, Ekaterina M., Shmakova, Anna A., Tanygina, Daria Yu, Ivashkina, Olga I., Anokhin, Konstantin V., Karagyaur, Maxim N., Zvereva, Maria I., Rubina, Kseniya A., Tkachuk, Vsevolod A., Semina, Ekaterina V.

“…Urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored receptor of urokinase (uPA), which is involved in brain development, nerve…”
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Preliminary assessment of the possibility of using urokinase uPA and urokinase receptor uPAR as universal diagnostic criteria in patients with colorectal and gastric adenocarcinoma by Klimovich, Polina S., Rubina, Ksenia A., Mironov, Nikita A., Kakotkin, Viktor V., Oleynikova, Nina A., Mal`kov, Pavel G., Kubyshkin, Valery A., Galliamov, Eduard A., Agapov, Mikhail A., Semina, Ekaterina V.

“…Background. Lack of universal diagnostic parameters that can accurately and reliably diagnose presence of a malignant neoplasm, anticancer drug effectiveness…”
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A Bicistronic Plasmid Encoding Brain-Derived Neurotrophic Factor and Urokinase Plasminogen Activator Stimulates Peripheral Nerve Regeneration After Injury by Karagyaur, Maxim, Rostovtseva, Alexandra, Semina, Ekaterina, Klimovich, Polina, Balabanyan, Vadim, Makarevich, Pavel, Popov, Vladimir, Stambolsky, Dmitry, Tkachuk, Vsevolod

“…Timely nerve restoration is an important factor for the successful regeneration of tissues and organs. It is known that axon regeneration following nerve…”
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Urokinase and urokinase receptor participate in regulation of neuronal migration, axon growth and branching by Semina, Ekaterina, Rubina, Kseniya, Sysoeva, Veronika, Rysenkova, Karina, Klimovich, Polina, Plekhanova, Olga, Tkachuk, Vsevolod

“…Recent findings indicate the significant contribution of urokinase and urokinase receptor (uPA and uPAR) in the processes of nerve regeneration, however, their…”
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