Search Results - "Klimova, Elena"

Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments by Martínez-Klimova, Elena, Aparicio-Trejo, Omar Emiliano, Tapia, Edilia, Pedraza-Chaverri, José

“…Renal fibrosis is the common pathway for most forms of progressive renal disease. The Unilateral Ureteral Obstruction (UUO) model is used to cause renal…”
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Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction by Martínez‐Klimova, Elena, Aparicio‐Trejo, Omar Emiliano, Gómez‐Sierra, Tania, Jiménez‐Uribe, Alexis Paulina, Bellido, Belen, Pedraza‐Chaverri, José

“…Obstructive nephropathy favors the progression to chronic kidney disease (CKD), a severe health problem worldwide. The unilateral ureteral obstruction (UUO)…”
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Nordihydroguaiaretic Acid: From Herbal Medicine to Clinical Development for Cancer and Chronic Diseases by Manda, Gina, Rojo, Ana I, Martínez-Klimova, Elena, Pedraza-Chaverri, José, Cuadrado, Antonio

“…Nordihydroguaiaretic acid (NDGA) is a phenolic lignan obtained from , the creosote bush found in Mexico and USA deserts, that has been used in traditional…”
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Chronic impairment of mitochondrial bioenergetics and β-oxidation promotes experimental AKI-to-CKD transition induced by folic acid by Aparicio-Trejo, Omar Emiliano, Avila-Rojas, Sabino Hazael, Tapia, Edilia, Rojas-Morales, Pedro, León-Contreras, Juan Carlos, Martínez-Klimova, Elena, Hernández-Pando, Rogelio, Sánchez- Lozada, Laura Gabriela, Pedraza-Chaverri, José

“…Recent studies suggest that mitochondrial bioenergetics and oxidative stress alterations may be common mechanisms involved in the progression of renal damage…”
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Bis-cations with two 2,3-diferrocenylcyclopropenium fragments stabilized with diamino-alkanes: Synthesis and cytotoxic activity by García-Valdés, Jesús, Sánchez García, Jessica J., Sánchez-Castell, Alberto, Alpizar-Mora, Ana G., Flores-Álamo, Marcos, Martínez-Klimova, Elena, Ramírez Apan, Teresa, Klimova, Elena I.

“…Bis-cations with two 2,3-diferrocenylcyclopropenium fragments 3a–d, and the cis-2-(1,2-diferrocenylvinyl)-2-imidazolinium tetrafluoroborates 4a, d or the…”
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Diferrocenyl(areno)oxazoles, spiro(arenooxazole)cyclopropenes, quinolines and areno[1,4-]oxazines: Synthesis, characterization and study of their antitumor activity by Sánchez García, Jessica J., Flores-Álamo, Marcos, Martínez-Klimova, Elena, Ramírez Apan, Teresa, Klimova, Elena I.

“…A novel 2-(Z,E-1,2-diferrocenylvinyl)arenooxazoles 4a-f and 5a-e (24–32%, 2:1, respectively),…”
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Novel heterogeneous basic catalysts for biodiesel production: Sodium titanate nanotubes doped with potassium by Hernández-Hipólito, Patricia, Juárez-Flores, Nohemí, Martínez-Klimova, Elena, Gómez-Cortés, Antonio, Bokhimi, Xim, Escobar-Alarcón, Luis, Klimova, Tatiana E.

“…•Synthesis of sodium titanate nanotubes doped with potassium by the Kasuga method.•Optimal synthesis conditions for sodium titanate nanotubes doped with…”
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Natural antioxidants' effects on endoplasmic reticulum stress-related diseases by Reyes-Fermín, Laura María, Aparicio-Trejo, Omar Emiliano, Avila-Rojas, Sabino Hazael, Gómez-Sierra, Tania, Martínez-Klimova, Elena, Pedraza-Chaverri, José

“…Endoplasmic reticulum (ER) stress is a normal molecular process induced by the over-accumulation of misfolded or unfolded proteins. ER stress induces the…”
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The Amoebicidal Activity of Diferrocenyl Derivatives: A Significant Dependence on the Electronic Environment by Toledano-Magaña, Yanis, Néquiz, Mario, Valenzuela-Salas, Lucía Margarita, Sánchez-García, Jessica J, Galindo-Murillo, Rodrigo, García-Ramos, Juan Carlos, Klimova, Elena I

“…Amoebiasis is the second leading cause of death worldwide associated with parasitic disease and is becoming a critical health problem in low-income countries,…”
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Low molecular weight cytotoxic components (DAMPs) form the post-COVID-19 syndrome by Klimova, Elena M., Bozhkov, Anatoly I., Lavinska, Olena V., Drozdova, Larisa A., Kurhuzova, Nataliia I.

“…•The duration of post-COVID-19 symptoms is associated with neutrophil dysfunction and the formation of a specific humoral immunological pattern that performs…”
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Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin by Avila-Rojas, Sabino Hazael, Aparicio-Trejo, Omar Emiliano, Briones-Herrera, Alfredo, Medina-Campos, Omar Noel, Reyes-Fermín, Laura María, Martínez-Klimova, Elena, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Tapia, Edilia, Pedraza-Chaverri, José

“…Curcumin has protective effects in several acute kidney injury models, including that induced by potassium dichromate (K2Cr2O7). The protective effect of…”
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Synthesis, characterization and electrochemistry of diferrocenyl-1,3-thiazoles, 1,3-oxathiolanes, benzo-[b]-1,4-oxathiepines and ethyl 2-propenethioates by Klimova, Elena I., Rubio, Carlos Guerrero, García-Valdés, Jesús, Nuñez-Cruz, Eder, Martínez-Klimova, Elena, Beletskaya, Irina P., Flores-Álamo, Marcos, Sánchez García, Jessica J.

“…2,3-Diferrocenylcyclopropenium salts react with bis-1,4-N,S- and bis-1,4-O,S-nucleophiles to yield: (1′,2′-diferrocenylvinyl)-1,3-thiazoles 6-8;…”
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Polycyclic ferrocenyl(dihydro)thiazepine derivatives: Diastereo-selective synthesis, characterization, electrochemical behavior, theoretical and biological investigation by Sánchez García, Jessica J., Toledano-Magaña, Yanis, Flores-Alamo, Marcos, Martínez-Klimova, Elena, Galindo-Murillo, Rodrigo, Hernández-Ayala, Luis F., Ortiz-Frade, Luis, García-Ramos, Juan C., Klimova, Elena I.

“…The reaction of E-2-ferrocenylmethylidenetetralones and E,E-2,6-bis-(ferrocenylmethylidene)-cyclohexanone with 2-aminothiophenol proceed with high…”
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Synthesis of flutamide-conjugates by Medina-Rojas, Julio César, Castillo-Rodríguez, Irving Osiel, Martínez-Klimova, Elena, Ramírez-Ápan, Teresa, Hernández-Ortega, Simón, Martínez-García, Marcos

“…[Display omitted] •We processed structural design and extended modification based on the flutamide structure.•A series of flutamide-conjugates were obtained…”
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Biodiesel production with nanotubular sodium titanate as a catalyst by Hernández-Hipólito, Patricia, García-Castillejos, Montserrat, Martínez-Klimova, Elena, Juárez-Flores, Nohemí, Gómez-Cortés, Antonio, Klimova, Tatiana E.

“…•Biodiesel synthesis from soybean oil and methanol with solid base catalyst.•Nanotubular sodium titanate as a catalyst for biodiesel production.•Studied…”
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Rearrangements of diferrocenylcyclopropenium ions in the reactions with bis-1,4-O,S-nucleophiles by García, Jessica J. Sánchez, Klimova, Elena I.

“…[Display omitted] Reactions of 3-R-1,2-diferrocenylcyclopropenium ions (R is 4-morpholino or SMe) with 2-mercaptophenol or 2-mercaptoethanol proceed via a ring…”
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Synthesis and anticancer activity of open-resorcinarene conjugates by Daniel Pedro-Hernández, Luis, Hernández-Montalbán, Carlos, Martínez-Klimova, Elena, Ramírez-Ápan, Teresa, Martínez-García, Marcos

“…[Display omitted] The first example of conjugation of open-resorcinarenes with chlorambucil, ibuprofen, naproxen and indomethacin are presented. The cytotoxic…”
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Divide et Impera: Drp1-mediated Mitochondrial Fission in Glioma Malignancy by Eugenio-Pérez, Dianelena, Briones-Herrera, Alfredo, Martínez-Klimova, Elena, Pedraza-Chaverri, José

“…Mitochondria are pivotal organelles involved in vital cellular functions, including energy generation, reactive oxygen species and calcium signaling, as well…”
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Transformations of (ferrocenylmethylidene)malononitrile under the action of molecular sulfur and NaHS by Sánchez García, Jessica J., Huerta Vargas, Gustavo, Flores-Alamo, Marcos, Klimova, Elena I.

“…[Display omitted] Reaction of (ferrocenylmethylidene)malononitrile with molecular sulfur and NaHS in PriOH/H2O medium gives (di)ferrocenyl-substituted…”
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Knowledge creation, knowledge impact and knowledge diffusion: how do they connect with higher education? by Dobrovolska, Olena, Sonntag, Ralph, Buschendorf, Susan, Klimova, Elena, Ortmanns, Wolfgang

“…Knowledge-based economy causes changes in the higher education system: university graduates must have the ability to constantly learn and improve their skills,…”
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