Search Results - "Klimontov, V. V."

Predictors of success and failure in achieving glycemic control targets in patients with type 2 diabetes on basal insulin: review of the real-world evidence studies by Klimontov, V. V.

“…Basal insulin (BI) is the main therapeutic option for patients with type 2 diabetes (T2D) who have not reached glycemic targets on oral antidiabetic drugs…”
Get full text

Bioinformatic Reconstruction and Analysis of Gene Networks Related to Glucose Variability in Diabetes and Its Complications by Saik, Olga V, Klimontov, Vadim V

“…Glucose variability (GV) has been recognized recently as a promoter of complications and therapeutic targets in diabetes. The aim of this study was to…”
Get full text

Glucose Variability: How Does It Work? by Klimontov, Vadim V., Saik, Olga V., Korbut, Anton I.

“…A growing body of evidence points to the role of glucose variability (GV) in the development of the microvascular and macrovascular complications of diabetes…”
Get full text

Open source automated insulin delivery systems: experience of russian patients by Klimontov, V. V., Shishin, K. S.

“…Open source closed loop automated insulin delivery (CL-AID) systems are increasingly used in the treatment of diabetes. Not being officially approved, such…”
Get full text

Open source automated insulin delivery systems: benefits, limitations and challenges in diabetes care by Shishin, K. S., Klimontov, V. V.

“…Open source closed loop automated insulin delivery (CL-AID) systems are increasingly used in the treatment of diabetes. Assembled on a do-it-yourself (DIY)…”
Get full text

Сytokines as promising diagnostic and prognostic biomarkers of microvascular complications of diabetes by Klimontov, V. V., Mavlianov, К. R.

“…Classical knowledge about the pathogenesis of diabetes and its complications in recent years has been supplemented by ideas about the role of chronic…”
Get full text

Gene Networks of Hyperglycemia, Diabetic Complications, and Human Proteins Targeted by SARS-CoV-2: What Is the Molecular Basis for Comorbidity? by Saik, Olga V., Klimontov, Vadim V.

“…People with diabetes are more likely to have severe COVID-19 compared to the general population. Moreover, diabetes and COVID-19 demonstrate a certain…”
Get full text

Markers of chronic low-grade inflammation and serum cytokine levels in patients with type 1 diabetes: associations with time in ranges and glucose variability by Mavlianova, K. R., Semenova, Ju. F., Orlov, N. B., Klimontov, V. V.

“…BACKGROUND: Increased glucose variability is recognized as a risk factor for vascular diabetic complications. It is assumed that deteriorating effect of GV on…”
Get full text

Reference values of 24-hour, day-time and nocturnal glucose variability parameters in subjects with normal glucose tolerance by Semenova, Ju. F., Klimontov, V. V.

“…BACKGROUND: Glucose variability (GV) is recognized as a risk factor for microvascular and macrovascular complications of diabetes and hypoglycemia. A number of…”
Get full text

Hypoglycemia, Vascular Disease and Cognitive Dysfunction in Diabetes: Insights from Text Mining-Based Reconstruction and Bioinformatics Analysis of the Gene Networks by Saik, Olga V, Klimontov, Vadim V

“…Hypoglycemia has been recognized as a risk factor for diabetic vascular complications and cognitive decline, but the molecular mechanisms of the effect of…”
Get full text

Medical Genetics, Genomics and Bioinformatics Aid in Understanding Molecular Mechanisms of Human Diseases by Orlov, Yuriy L., Anashkina, Anastasia A., Klimontov, Vadim V., Baranova, Ancha V.

“…Molecular mechanisms of human disease progression often have complex genetic underpinnings, and sophisticated sequencing approaches coupled with advanced…”
Get full text

SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes by Korbut, Anton I, Taskaeva, Iuliia S, Bgatova, Nataliya P, Muraleva, Natalia A, Orlov, Nikolai B, Dashkin, Maksim V, Khotskina, Anna S, Zavyalov, Evgenii L, Konenkov, Vladimir I, Klein, Thomas, Klimontov, Vadim V

“…Recent data have indicated the emerging role of glomerular autophagy in diabetic kidney disease. We aimed to assess the effect of the SGLT2 inhibitor…”
Get full text

Factors associated with high glucose variability in patients with type 1 diabetes by Klimontov, V. V., Semenova, Ju. F., Korbut, A. I.

“…BACKGROUND : High glucose variability (GV) is recognized as a risk factor for vascular diabetic complications and hypoglycemia. Factors affecting GV in…”
Get full text

Serum biomarkers associated with liver fibrosis in patients with type 2 diabetes by Krasner, Y. A., Romanov, V. V., Fazullina, O. N., Osipenko, M. F., Klimontov, V. V.

“…BACKGROUND: The diagnosis of liver fibrosis is an important task in the management of patients with non-alcoholic fatty liver disease (NAFLD) and type 2…”
Get full text

Lymphatic system and adipose tissue: Crosstalk in health and disease by Klimontov, V. V., Bulumbaeva, D. M.

“…The lymphatic system (LS) is one of the main integrative systems of the body, providing protective and transport functions. In recent years, interactions…”
Get full text

1,5-anhydroglucitol in diabetes: its role in diagnostics, screening, glycemic status assessment, and the prediction of complications by Klimontov, V. V., Dashkin, M. V.

“…1,5-anhydroglucitol (1,5-AG) is a short-term indicator of glycemic status, reflecting hyperglycemic glucose excursions over the prior 12 weeks. As glucose…”
Get full text

Medical Genetics, Genomics and Bioinformatics-2022 by Klimontov, Vadim V, Koshechkin, Konstantin A, Orlova, Nina G, Sekacheva, Marina I, Orlov, Yuriy L

“…The analysis of molecular mechanisms of disease progression challenges the development of bioinformatics tools and omics data integration [...]…”
Get full text

Serum level of proteins involved in apoptosis and autophagy in patients with type 2 diabetes and non-alcoholic fatty liver disease by Krasner, Ya. A., Romanov, V. V., Fazullina, O. N., Osipenko, M. F., Klimontov, V. V.

“…Aim of the study was to estimate the blood serum level of microtubule-associated protein 1 light chain 3 alpha (MAP1LC3alpha), beclin-1 (BECN-1), Bcl-2…”
Get full text

Association of carotid atherosclerosis and peripheral artery disease in patients with type 2 diabetes: risk factors and biomarkers by Koroleva, E. A., Khapaev, R. S., Lykov, A. P., Korbut, A. I., Klimontov, V. V.

“…BACKGROUND: Carotid atherosclerosis (CA) and lower extremity peripheral artery disease (PAD) is a common and potentially life-threatening comorbidity in…”
Get full text

Artificial intelligence in diabetology by Klimontov, V. V., Berikov, V. B., Saik, O. V.

“…This review presents the applications of artificial intelligence for the study of the mechanisms of diabetes development and generation of new technologies of…”
Get full text