Search Results - "Klimcáková, L"
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Variation in CDKAL1 gene is associated with therapeutic response to sulphonylureas
Published in Physiological research (01-01-2012)“…The aim of the present pilot pharmacogenetic study was to analyse quantitative effects of sulphonylurea treatment in addition to metformin on parameters of…”
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Pharmacogenomic association between a variant in SLC47A1 gene and therapeutic response to metformin in type 2 diabetes
Published in Diabetes, obesity & metabolism (01-02-2013)“…Pharmacogenetic studies revealed that variants in genes related to the pharmacokinetics of metformin were associated with glucose‐lowering effect of metformin…”
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A missense variant in GLP1R gene is associated with the glycaemic response to treatment with gliptins
Published in Diabetes, obesity & metabolism (01-09-2016)“…Gliptins act by increasing endogenous incretin levels. Glucagon‐like peptide‐1 receptor (GLP1R) and glucose‐dependent insulinotropic peptide receptor (GIPR)…”
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Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta‐Analysis
Published in Clinical pharmacology and therapeutics (01-06-2017)“…Therapeutic response to metformin, a first‐line drug for type 2 diabetes (T2D), is highly variable, in part likely due to genetic factors. To date, metformin…”
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Effect of sulphonylurea treatment on glycaemic control is related to TCF7L2 genotype in patients with type 2 diabetes
Published in Diabetes, obesity & metabolism (2011)“…The aim of the present study was to analyse effects of sulphonylurea treatment on parameters of glycaemic control in relation to transcription factor 7-like 2…”
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Nucleic acid amplification technique for detection of Chlamydia trachomatis infection from clinical urogenital swabs
Published in Folia microbiologica (2007)“…An improved nucleic acid amplification test (NAAT) to detect Chlamydia trachomatis infections, based on PCR amplification within its cryptic plasmid (CT1/CT2…”
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Molecular detection of Ureaplasma urealyticum infection from clinical urogenital swabs
Published in Folia microbiologica (2007)“…A simple nucleic acid amplification test (NAAT) was developed for detection of Ureaplasma urealyticum infection based on the PCR amplification of the urease…”
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Relationship of five type 2 diabetes candidate gene polymorphisms to the age at diagnosis of diabetes in the Slovakian population
Published in Bratislavské lékarské listy (2010)“…To examine the relationship between polymorphisms of five candidate genes for type 2 diabetes mellitus (T2DM) and the age at diagnosis of T2DM. 538 Slovakian…”
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Nucleic acid amplification technique for detection ofChlamydia trachomatis infection from clinical urogenital swabs
Published in Folia microbiologica (01-07-2007)“…An improved nucleic acid amplification test (NAAT) to detectChlamydia trachomatis infections, based on PCR amplification within its cryptic plasmid (CT1/CT2…”
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Molecular detection ofUreaplasma urealyticum infection from clinical urogenital swabs
Published in Folia microbiologica (01-07-2007)“…A simple nucleic acid amplification test (NAAT) was developed for detection ofUreaplasma urealyticum infection based on the PCR amplification of the urease…”
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Relationship of the CDKAL1 and KCNQ1 gene polymorphisms to the age at diagnosis of type 2 diabetes in the Slovakian population
Published in Vnitřní lékar̆stvĭ (01-02-2011)“…The association of CDKAL1 and KCNQ1 genes with type 2 diabetes mellitus (DM2T) was confirmed by several genome-wide association studies in both Caucasian and…”
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Epidermal growth factor receptor (EGFR) expression in colorectal cancer in Slovakia
Published in Journal of clinical oncology (20-06-2006)“…Abstract only 20103 Background: EGFR is involved in the epidermal growth factor pathway that regulates cellular processes and is associated with the…”
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