Search Results - "Klimaschewski, L"

Inhibition of fibroblast growth factor receptor 1 endocytosis promotes axonal branching of adult sensory neurons by Hausott, B, Rietzler, A, Vallant, N, Auer, M, Haller, I, Perkhofer, S, Klimaschewski, L

“…Abstract Fibroblast growth factors (FGFs) promote axon growth during development and regeneration of the nervous system. Among the four types of FGF receptors…”
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Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior by Sah, A, Schmuckermair, C, Sartori, S B, Gaburro, S, Kandasamy, M, Irschick, R, Klimaschewski, L, Landgraf, R, Aigner, L, Singewald, N

“…Adult neurogenesis has been implicated in affective disorders and the action of antidepressants (ADs) although the functional significance of this association…”
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Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons by Hausott, B, Schlick, B, Vallant, N, Dorn, R, Klimaschewski, L

“…Abstract Basic fibroblast growth factor (FGF-2) is up-regulated in response to a nerve lesion and promotes axonal regeneration by activation of the tyrosine…”
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Basic fibroblast growth factor isoforms promote axonal elongation and branching of adult sensory neurons in vitro by Klimaschewski, L, Nindl, W, Feurle, J, Kavakebi, P, Kostron, H

“…Synthesis of the multifunctional cytokine basic fibroblast growth factor (FGF-2) is up-regulated after sciatic nerve lesion. In this study, the effects of low…”
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Poor functional recovery and muscle polyinnervation after facial nerve injury in fibroblast growth factor-2−/− mice can be improved by manual stimulation of denervated vibrissal muscles by Seitz, M, Grosheva, M, Skouras, E, Angelova, S.K, Ankerne, J, Jungnickel, J, Grothe, C, Klimaschewski, L, Hübbers, C.U, Dunlop, S.A, Angelov, D.N

“…Abstract Functional recovery following facial nerve injury is poor. Adjacent neuromuscular junctions (NMJs) are “bridged” by terminal Schwann cells and…”
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Selective up-regulation of the vasodilator peptide apelin after dorsal root but not after spinal nerve injury by Lang, L, Ingorokva, S, Hausott, B, Vallant, N, Schmidt, S, Schwarzer, C, Klimaschewski, L

“…Abstract Regeneration of sensory neurons is limited in response to lesion of their central axons when compared to lesion of their peripheral axons. To identify…”
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Albumin-based nanoparticles as magnetic resonance contrast agents: I. Concept, first syntheses and characterisation by Stollenwerk, M. M, Pashkunova-Martic, I, Kremser, C, Talasz, H, Thurner, G. C, Abdelmoez, A. A, Wallnöfer, E. A, Helbok, A, Neuhauser, E, Klammsteiner, N, Klimaschewski, L, von Guggenberg, E, Fröhlich, E, Keppler, B, Jaschke, W, Debbage, P

“…To develop a platform for molecular magnetic resonance imaging, we prepared gadolinium-bearing albumin-polylactic acid nanoparticles in the size range 20-40 nm…”
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Differential neurotoxicity of tricyclic antidepressants and novel derivatives in vitro in a dorsal root ganglion cell culture model by Haller, I., Lirk, P., Keller, C., Wang, G. K., Gerner, P., Klimaschewski, L.

“…BACKGROUND AND OBJECTIVE:Tricyclic antidepressants are commonly employed orally to treat major depressive disorders and have been shown to be of substantial…”
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Expression of basic fibroblast growth factor isoforms in postmitotic sympathetic neurons: synthesis, intracellular localization and involvement in karyokinesis by Nindl, W, Kavakebi, P, Claus, P, Grothe, C, Pfaller, K, Klimaschewski, L

“…Low and high molecular weight isoforms of the mitogen and multifunctional cytokine basic fibroblast growth factor (FGF-2) are up-regulated in neurons and glial…”
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Regulation of clusterin expression following spinal cord injury by Klimaschewski, L, Obermüller, N, Witzgall, R

“…We have investigated the localization and regulation of a putative extracellular chaperone, clusterin, in the rat spinal cord after lesion. In control animals,…”
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Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 map kinase in vitro and in vivo by Lirk, P., Haller, I., Klimaschewski, L., Gerner, P.

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Nitric Oxide Synthase in Cardiac Nerve Fibers and Neurons of Rat and Guinea Pig Heart by Klimaschewski, Lars, Kummer, Wolfgang, Mayer, Bernd, Couraud, Jean Yves, Preissler, Ulrike, Philippin, Bärbel, Heym, Christine

“…Participation of nitric oxide (NO) in the autonomic innervation of rat and guinea pig hearts was investigated by applying the NADPH diaphorase technique and…”
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Mitigation of lidocaine-induced neurotoxicity - a comparison of compartmented and dissociated sensory neuron cultures: 8AP10-8 by Haller, I, Colvin, H P, Gerner, P, Klimaschewski, L, Lirk, P

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Target-dependent plasticity of galanin and vasoactive intestinal peptide in the rat superior cervical ganglion after nerve lesion and re-innervation by Klimaschewski, L., Grohmann, I., Heym, C.

“…The expression of the neuropeptides galanin and vasoactive intestinal peptide (VIP) is increased in subpopulations of sympathetic neurons after axotomy of the…”
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Expression pattern of candidate cell death effector proteins Bax, Bcl-2, Bcl-X, and c-Jun in sensory and motor neurons following sciatic nerve transection in the rat by Gillardon, F, Klimaschewski, L, Wickert, H, Krajewski, S, Reed, J C, Zimmermann, M

“…Numerous studies have demonstrated a prolonged expression of c-Jun transcription factor in neurons following axotomy, and it has been hypothesized that c-Jun…”
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Ultrastructure of α-synuclein-positive aggregations in U373 astrocytoma and rat primary glial cells by Stefanova, N., Emgård, M., Klimaschewski, L., Wenning, G.K., Reindl, M.

“…Abnormal α-synuclein-positive glial cytoplasmic inclusions are found in Parkinson's disease, multiple system atrophy and dementia with Lewy bodies. We have…”
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Glial cell line-derived neurotrophic factor (GDNF) promotes axon outgrowth of dorsal root ganglia (DRG) neurons supplying porcine urinary bladder – an in vitro study by Kozłowska, A, Mikołajczyk, A, Klimaschewski, L, Majewski, M

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Fibroblast growth factor (FGF) promotes axon elongation in galanin expressing dorsal root ganglia (DRG) neurons supplying urinary bladder of the pig – an in vitro study by Kozłowska, A, Mikołajczyk, A, Klimaschewski, L, Majewski, M

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Plasticity of neuropeptide Y in the rat superior cervical ganglion in response to nerve lesion by Kroesen, S, Lang, S, Fischer-Colbrie, R, Klimaschewski, L

“…Axotomy of the rat superior cervical ganglion results in a two-fold increase of neuropeptide tyrosine as determined by radioimmunoassay. [9]On the other hand,…”
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Antisense oligodeoxynucleotides to bax mRNA promote survival of rat sympathetic neurons in culture by Gillardon, F., Zimmermann, M., Uhlmann, E., Krajewski, S., Reed, J.C., Klimaschewski, L.

“…Previous in vitro studies have shown that the presence of high levels of Bax protein accelerated the rate of cell death following growth factor deprivation and…”
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