Search Results - "Klijn, Catharina J.M"
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Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy
Published in Neurology (01-03-2016)“…OBJECTIVE:To investigate the histopathologic substrate of microbleeds detected on 7T postmortem MRI in autopsy cases with severe cerebral amyloid angiopathy…”
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Research Progresses in Understanding the Pathophysiology of Moyamoya Disease
Published in Cerebrovascular diseases (Basel, Switzerland) (01-01-2016)“…The pathogenesis of moyamoya disease (MMD) is still unknown. The detection of inflammatory molecules such as cytokines, chemokines and growth factors in MMD…”
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CT angiography spot sign in intracerebral hemorrhage predicts active bleeding during surgery
Published in Neurology (02-09-2014)“…OBJECTIVE:To determine whether the CT angiography (CTA) spot sign marks bleeding complications during and after surgery for spontaneous intracerebral…”
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Cerebral Perfusion and the Occurrence of Nonfocal Transient Neurological Attacks
Published in Cerebrovascular diseases (Basel, Switzerland) (01-09-2019)“…Nonfocal transient neurological attacks (TNAs) are associated with an increased risk of cardiac events, stroke and dementia. Their etiology is still unknown…”
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Neuropsychiatric symptoms with focus on apathy and irritability in sporadic and hereditary cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (06-04-2024)“…Neuropsychiatric symptoms (NPS) may affect cognition, but their burden in cerebral amyloid angiopathy (CAA), one of the main causes of intracerebral hemorrhage…”
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Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy
Published in Alzheimer's research & therapy (23-04-2024)“…Neurofilament light chain (NFL) is a biomarker for neuroaxonal damage and glial fibrillary acidic protein (GFAP) for reactive astrocytosis. Both processes…”
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Stroke incidence in young adults according to age, subtype, sex, and time trends
Published in Neurology (21-05-2019)“…OBJECTIVETo investigate incidence of stroke and its subtypes in young adults, according to sex and age, and to study trends over time. METHODSWe established a…”
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Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study
Published in Stroke (1970) (01-01-2019)“…BACKGROUND AND PURPOSE—Cerebral small vessel disease (SVD) is a major cause of stroke and dementia, but underlying disease mechanisms are still largely…”
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Location-specific risk factors for intracerebral hemorrhage: Systematic review and meta-analysis
Published in Neurology (29-09-2020)“…OBJECTIVETo conduct a systematic review and meta-analysis of studies reporting on risk factors according to location of the intracerebral hemorrhage. METHODSWe…”
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Time trends in incidence, case fatality, and mortality of intracerebral hemorrhage
Published in Neurology (13-10-2015)“…OBJECTIVE:To assess age- and sex-specific trends in incidence and 30-day and 1-year case fatality of intracerebral hemorrhage (ICH) in the Netherlands…”
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Effect of Antihypertensive Medication on Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis
Published in Stroke (1970) (01-06-2018)“…BACKGROUND AND PURPOSE—Hypertension is an important risk factor for cerebral small vessel disease. We aimed to study the effect of antihypertensive medication…”
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Nonlinear temporal dynamics of cerebral small vessel disease: The RUN DMC study
Published in Neurology (10-10-2017)“…OBJECTIVE:To investigate the temporal dynamics of cerebral small vessel disease (SVD) by 3 consecutive assessments over a period of 9 years, distinguishing…”
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RNA-Sequencing Highlights Inflammation and Impaired Integrity of the Vascular Wall in Brain Arteriovenous Malformations
Published in Stroke (1970) (01-01-2020)“…BACKGROUND AND PURPOSE—Interventional treatment of unruptured brain arteriovenous malformations (BAVMs) has become increasingly controversial. Because medical…”
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Variation in Restarting Antithrombotic Drugs at Hospital Discharge After Intracerebral Hemorrhage
Published in Stroke (1970) (01-09-2014)“…BACKGROUND AND PURPOSE—Whether intracerebral hemorrhage (ICH) survivors should restart antithrombotic drugs is unknown. We analyzed the frequency of restarting…”
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Comparison of telephone and face-to-face assessment of the modified Rankin Scale
Published in Cerebrovascular diseases (Basel, Switzerland) (01-01-2010)“…A structured interview improves the reliability of the modified Rankin Scale (mRS), a commonly used functional outcome scale in stroke trials. Telephone…”
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Computed Tomography Angiography Spot Sign, Hematoma Expansion, and Functional Outcome in Spontaneous Cerebellar Intracerebral Hemorrhage
Published in Stroke (1970) (01-09-2021)“…The computed tomography angiography spot sign is associated with hematoma expansion, case fatality, and poor functional outcome in spontaneous supratentorial…”
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The role of small diffusion-weighted imaging lesions in cerebral small vessel disease
Published in Neurology (22-10-2019)“…OBJECTIVETo investigate the prevalence of asymptomatic diffusion-weighted imaging–positive (DWI+) lesions in individuals with cerebral small vessel disease…”
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Blood pressure levels and the risk of intracerebral hemorrhage after ischemic stroke
Published in Neurology (10-01-2017)“…OBJECTIVE:To investigate the association between blood pressure (BP) levels and risk of intracerebral hemorrhage (ICH) after ischemic stroke. METHODS:We…”
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Safety and technical efficacy of early minimally invasive endoscopy-guided surgery for intracerebral haemorrhage: the Dutch Intracerebral haemorrhage Surgery Trial pilot study
Published in Acta neurochirurgica (01-06-2023)“…Background Previous randomised controlled trials could not demonstrate that surgical evacuation of intracerebral haemorrhage (ICH) improves functional outcome…”
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