Search Results - "Klijn, Catharina J. M"
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Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial
Published in The Lancet (British edition) (15-02-2014)“…Summary Background The clinical benefit of preventive eradication of unruptured brain arteriovenous malformations remains uncertain. A Randomised trial of…”
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Treatment of Brain Arteriovenous Malformations: A Systematic Review and Meta-analysis
Published in JAMA : the journal of the American Medical Association (09-11-2011)“…CONTEXT: Outcomes following treatment of brain arteriovenous malformations (AVMs) with microsurgery, embolization, stereotactic radiosurgery (SRS), or…”
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Participatory methods used in the evaluation of medical devices: a comparison of focus groups, interviews, and a survey
Published in BMC health services research (12-04-2024)“…Stakeholder engagement in evaluation of medical devices is crucial for aligning devices with stakeholders' views, needs, and values. Methods for these…”
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Proximity extension assay in cerebrospinal fluid identifies neurofilament light chain as biomarker of neurodegeneration in sporadic cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (14-05-2024)“…Sporadic cerebral amyloid angiopathy (sCAA) is a disease characterised by the progressive deposition of the amyloid beta (Aβ) in the cerebral vasculature,…”
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Cerebral small vessel disease: from a focal to a global perspective
Published in Nature reviews. Neurology (01-07-2018)“…Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to…”
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The relation of a cerebrospinal fluid profile associated with Alzheimer's disease with cognitive function and neuropsychiatric symptoms in sporadic cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (04-05-2024)“…Patients with sporadic cerebral amyloid angiopathy (sCAA) frequently report cognitive or neuropsychiatric symptoms. The aim of this study is to investigate…”
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Altered brain expression and cerebrospinal fluid levels of TIMP4 in cerebral amyloid angiopathy
Published in Acta neuropathologica communications (24-06-2024)“…Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology, involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA…”
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Cognitive Functions in Children and Adults with Moyamoya Vasculopathy: A Systematic Review and Meta-Analysis
Published in Journal of stroke (01-09-2018)“…Patients with moyamoya vasculopathy (MMV) may experience cognitive impairment, but its reported frequency, severity, and nature vary. In a systematic review…”
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Decreased ratios of matrix metalloproteinases to tissue-type inhibitors in cerebrospinal fluid in sporadic and hereditary cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (30-01-2023)“…To evaluate the potential of cerebrospinal fluid (CSF) levels of matrix metalloproteinases and tissue-type inhibitors (MMP; TIMP), and ratios of MMPs to TIMPs,…”
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Plasma amyloid beta 42 is a biomarker for patients with hereditary, but not sporadic, cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (03-06-2023)“…The diagnosis of probable cerebral amyloid angiopathy (CAA) is currently mostly based on characteristics of brain MRI. Blood biomarkers would be a…”
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Haemodynamic stroke: clinical features, prognosis, and management
Published in Lancet neurology (01-10-2010)“…Summary Haemodynamic stroke is a type of ischaemic stroke that is caused by hypoperfusion rather than by embolism or local vasculopathy. It can be caused by…”
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Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients
Published in Acta neuropathologica communications (08-01-2024)“…Cerebral amyloid angiopathy (CAA) is a form of small vessel disease characterised by the progressive deposition of amyloid β protein in the cerebral…”
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Deep coma and diffuse white matter abnormalities caused by sepsis-associated encephalopathy
Published in The Lancet (British edition) (22-06-2013)“…Because of the deep coma and the diffuse and severely abnormal aspect of the white matter--both associated with poor outcome--discontinuation of treatment was…”
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No replicating evidence for anti‐amyloid‐β autoantibodies in cerebral amyloid angiopathy‐related inflammation
Published in Annals of clinical and translational neurology (01-10-2024)“…Objective Elevated levels of anti‐amyloid‐β (anti‐Aβ) autoantibodies in cerebrospinal fluid (CSF) have been proposed as a diagnostic biomarker for cerebral…”
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Limb-shaking transient ischaemic attacks in patients with internal carotid artery occlusion: a case-control study
Published in Brain (London, England : 1878) (01-03-2010)“…Limb-shaking is a specific clinical feature of transient ischaemic attacks that has been associated with a high-grade stenosis or occlusion of the internal…”
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MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy
Published in Acta neuropathologica communications (16-09-2021)“…Brain accumulation of amyloid-beta (Aβ) is a crucial feature in Alzheimer´s disease (AD) and cerebral amyloid angiopathy (CAA), although the pathophysiological…”
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Outcome after spontaneous and arteriovenous malformation-related intracerebral haemorrhage: population-based studies
Published in Brain (London, England : 1878) (01-02-2009)“…Spontaneous (non-traumatic) intracerebral haemorrhage (ICH) has a high case-fatality and leaves many survivors disabled. Clinical characteristics and outcome…”
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Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage
Published in Acta neuropathologica communications (06-07-2020)“…Abstract Cerebral amyloid angiopathy (CAA) is characterized by the deposition of the amyloid β (Aβ) protein in the cerebral vasculature and poses a major risk…”
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Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer’s disease, but not in cerebral amyloid angiopathy
Published in Alzheimer's research & therapy (24-09-2021)“…Abstract Background Neuroleukin (NLK) is a protein with neurotrophic properties and is present in a proportion of senile plaques and amyloid laden vessels. It…”
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Apixaban versus Antiplatelet drugs or no antithrombotic drugs after anticoagulation-associated intraCerebral HaEmorrhage in patients with Atrial Fibrillation (APACHE-AF): study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (04-09-2015)“…There is a marked lack of evidence on the optimal prevention of ischaemic stroke and other thromboembolic events in patients with non-valvular atrial…”
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