Search Results - "Kleymenov, Sergey Yu"
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Kinetics of Thermal Denaturation and Aggregation of Bovine Serum Albumin
Published in PloS one (21-04-2016)“…Thermal aggregation of bovine serum albumin (BSA) has been studied using dynamic light scattering, asymmetric flow field-flow fractionation and analytical…”
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A change in the aggregation pathway of bovine serum albumin in the presence of arginine and its derivatives
Published in Scientific reports (21-06-2017)“…Chemical chaperones including arginine and its derivatives are widely used by biochemists working on the design of agents, which are able to efficiently…”
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3
A thermal after-effect of UV irradiation of muscle glycogen phosphorylase b
Published in PloS one (07-12-2017)“…Different test systems are used to characterize the anti-aggregation efficiency of molecular chaperone proteins and of low-molecular-weight chemical…”
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A change in the pathway of dithiothreitol-induced aggregation of bovine serum albumin in the presence of polyamines and arginine
Published in International journal of biological macromolecules (01-11-2017)“…•To characterize the mechanisms of protein aggregation, the plots of the hydrodynamic radius of protein aggregates versus the portion of aggregated protein…”
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Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP
Published in Communications biology (28-04-2023)“…Fasciclins (FAS1) are ancient adhesion protein domains with no common small ligand binding reported. A unique microalgal FAS1-containing astaxanthin…”
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Polyamines putrescine and spermidine as modulators of protein aggregation rate: The effect on DTT-induced aggregation of α-lactalbumin
Published in Biochimie (20-07-2024)“…Protein aggregation is undesirable for cells due to its possible toxicity, and is also undesirable in biotechnology and pharmaceuticals. Polyamines are known…”
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Structural basis for the carotenoid binding and transport function of a START domain
Published in Structure (London) (01-12-2022)“…STARD3, a steroidogenic acute regulatory lipid transfer protein, was identified as a key xanthophyll-binding protein in the human retina. STARD3 and its…”
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The mechanism of thermal aggregation of glutamate dehydrogenase. The effect of chemical chaperones
Published in Biochimie (01-04-2022)“…Chemical chaperones are low-molecular compounds counteracting protein aggregation. Understanding of the mechanism of their effects is key to their potential…”
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Kinetic regime of Ca2+ and Mg2+-induced aggregation of phosphorylase kinase at 40 °C
Published in International journal of biological macromolecules (01-10-2019)“…Many functions of phosphorylase kinase (PhK) are regulated by Ca2+ and Mg2+ ions. Ca2+ and Mg2+ ions stimulate activity of PhK, induce the changes in the…”
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10
Structural plasticity and thermal stability of the histone-like protein from Spiroplasma melliferum are due to phenylalanine insertions into the conservative scaffold
Published in Journal of biomolecular structure & dynamics (10-12-2018)“…The histone-like (HU) protein is one of the major nucleoid-associated proteins of the bacterial nucleoid, which shares high sequence and structural similarity…”
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Does the Crowded Cell-like Environment Reduce the Chaperone-like Activity of α-Crystallin?
Published in Biochemistry (Easton) (13-12-2011)“…The effect of crowding on the chaperone-like activity of α-crystallin has been studied using aggregation of UV-irradiated glycogen phosphorylase b (Phb) from…”
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Mechanism of aggregation of UV-irradiated βL-crystallin
Published in Experimental eye research (01-01-2011)“…Thermal denaturation and aggregation of UV-irradiated βL-crystallin from eye lenses of steers have been studied. The data on size-exclusion chromatography and…”
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13
Quantification of anti-aggregation activity of UV-irradiated α-crystallin
Published in International journal of biological macromolecules (01-02-2015)“…Ultraviolet radiation is a risk factor for cataractogenesis. It is believed that enhanced rates of lens opacification and cataract formation are the results of…”
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14
Kinetic regime of Ca 2+ and Mg 2+ -induced aggregation of phosphorylase kinase at 40 °C
Published in International journal of biological macromolecules (01-10-2019)“…Many functions of phosphorylase kinase (PhK) are regulated by Ca and Mg ions. Ca and Mg ions stimulate activity of PhK, induce the changes in the tertiary and…”
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15
Thermal denaturation and aggregation of apoform of glycogen phosphorylase b. Effect of crowding agents and chaperones
Published in Biopolymers (01-05-2014)“…ABSTRACT The effect of protein and chemical chaperones and crowders on thermal stability and aggregation of apoform of rabbit muscle glycogen phosphorylase b…”
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Dual effect of arginine on aggregation of phosphorylase kinase
Published in International journal of biological macromolecules (01-07-2014)“…Arginine is widely used in biotechnology as a folding enhancer and aggregation suppressor. However, its action on the stability of complexly organized…”
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17
Engineering catalytic properties and thermal stability of plant formate dehydrogenase by single-point mutations
Published in Protein engineering, design and selection (01-11-2012)“…The analysis of the 3D model structure of the ternary complex of recombinant formate dehydrogenase from soya Glycine max (EC 1.2.1.2., SoyFDH) with bound NAD+…”
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Effect of Additional Amino Acid Replacements on the Properties of Multi-point Mutant Bacterial Formate Dehyderogenase PseFDH SM4S
Published in Actanaturae (01-01-2022)“…Formate dehydrogenase from Pseudomonas sp. 101 bacterium (PseFDH, EC 1.2.1.2) is a research model for the elucidation of the catalytic mechanism of 2-oxyacid…”
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Effect of proline on thermal inactivation, denaturation and aggregation of glycogen phosphorylase b from rabbit skeletal muscle
Published in Biophysical chemistry (01-04-2009)“…It has been shown that the relatively low concentrations of proline (0.1 M) have a slight accelerating effect on thermal aggregation of glycogen phosphorylase…”
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Kinetics of aggregation of UV-irradiated glyceraldehyde-3-phosphate dehydrogenase from rabbit skeletal muscle. Effect of agents possessing chaperone-like activity
Published in Biophysical chemistry (01-04-2012)“…An aggregation test system based on the aggregation of UV-irradiated glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from rabbit skeletal muscle has been…”
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