Search Results - "Klett, K."

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
Get full text

AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury by Hinkel, Rabea, Ramanujam, Deepak, Kaczmarek, Veronika, Howe, Andrea, Klett, Katharina, Beck, Christina, Dueck, Anne, Thum, Thomas, Laugwitz, Karl-Ludwig, Maegdefessel, Lars, Weber, Christian, Kupatt, Christian, Engelhardt, Stefan

“…miR-21 is a central regulator of cardiac fibrosis, and its inhibition in small-animal models has been shown to be an effective antifibrotic strategy in various…”
Get full text

Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs by Baehr, Andrea, Umansky, Kfir Baruch, Bassat, Elad, Jurisch, Victoria, Klett, Katharina, Bozoglu, Tarik, Hornaschewitz, Nadja, Solyanik, Olga, Kain, David, Ferraro, Bartolo, Cohen-Rabi, Renee, Krane, Markus, Cyran, Clemens, Soehnlein, Oliver, Laugwitz, Karl Ludwig, Hinkel, Rabea, Kupatt, Christian, Tzahor, Eldad

“…Background: Ischemic heart diseases are leading causes of death and reduced life quality worldwide. Although revascularization strategies significantly reduce…”
Get full text

4928Regional application of LNA-92a inhibits development of heart failure in chronic myocardial ischemia by Hinkel, R, Klett, K, Baehr, A, Bonauer, A, Fischer, A, Weber, C, Laugwitz, K L, Dimmeler, S, Kupatt, C

Get full text

The Influence of Naproxen on Biological Factors in Leukocyte-Rich Platelet-Rich Plasma: A Prospective Comparative Study by Mannava, Sandeep, Whitney, Kaitlyn E., Kennedy, Mitchell I., King, Jill, Dornan, Grant J., Klett, Katarina, Chahla, Jorge, Evans, Thos A., Huard, Johnny, LaPrade, Robert F.

“…To quantify and compare normative catabolic and anabolic factor concentrations in leukocyte-rich platelet-rich plasma (LR-PRP) at various time points,…”
Get full text

Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes by Meagher, Nicola S, Gorringe, Kylie L, Wakefield, Matthew, Bolithon, Adelyn, Pang, Chi Nam Ignatius, Chiu, Derek S, Anglesio, Michael S, Mallitt, Kylie-Ann, Doherty, Jennifer A, Harris, Holly R, Schildkraut, Joellen M, Berchuck, Andrew, Cushing-Haugen, Kara L, Chezar, Ksenia, Chou, Angela, Tan, Adeline, Alsop, Jennifer, Barlow, Ellen, Beckmann, Matthias W, Boros, Jessica, Bowtell, David D L, Brand, Alison H, Brenton, James D, Campbell, Ian, Cheasley, Dane, Cohen, Joshua, Cybulski, Cezary, Elishaev, Esther, Erber, Ramona, Farrell, Rhonda, Fischer, Anna, Fu, Zhuxuan, Gilks, Blake, Gill, Anthony J, Gourley, Charlie, Grube, Marcel, Harnett, Paul R, Hartmann, Arndt, Hettiaratchi, Anusha, Høgdall, Claus K, Huzarski, Tomasz, Jakubowska, Anna, Jimenez-Linan, Mercedes, Kennedy, Catherine J, Kim, Byoung-Gie, Kim, Jae-Weon, Kim, Jae-Hoon, Klett, Kayla, Koziak, Jennifer M, Lai, Tiffany, Laslavic, Angela, Lester, Jenny, Leung, Yee, Li, Na, Liauw, Winston, Lim, Belle W X, Linder, Anna, Lubiński, Jan, Mahale, Sakshi, Mateoiu, Constantina, McInerny, Simone, Menkiszak, Janusz, Minoo, Parham, Mittelstadt, Suzana, Morris, David, Orsulic, Sandra, Park, Sang-Yoon, Pearce, Celeste Leigh, Pearson, John V, Pike, Malcolm C, Quinn, Carmel M, Mohan, Ganendra Raj, Rao, Jianyu, Riggan, Marjorie J, Ruebner, Matthias, Salfinger, Stuart, Scott, Clare L, Shah, Mitul, Steed, Helen, Stewart, Colin J R, Subramanian, Deepak, Sung, Soseul, Tang, Katrina, Timpson, Paul, Ward, Robyn L, Wiedenhoefer, Rebekka, Thorne, Heather, Cohen, Paul A, Crowe, Philip, Fasching, Peter A, Gronwald, Jacek, Hawkins, Nicholas J, Høgdall, Estrid, Huntsman, David G, James, Paul A, Karlan, Beth Y, Kelemen, Linda E, Kommoss, Stefan, Konecny, Gottfried E, Modugno, Francesmary

“…Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis and lacks biomarkers to aid stage I adjuvant treatment…”
Get full text

P5384LNA-based miR132 inhibition is cardioprotective in a pig model of percutaneous transverse aortic constriction (pTAC) by Hinkel, R., Klett, K., Straub, S., Howe, A., Baktai, S., Kozlik-Feldmann, R., Thum, T., Kupatt, C.

Get full text

P4914LNA-based miR92a inhibition induces therapeutic neovascularization in a pig model of chronic myocardial ischemia by Hinkel, R., Klett, K., Fischer, A., Bonauer, A., Van Rooij, E., Zeiher, A., Dimmeler, S., Kupatt, C.

Get full text

Influence of Naproxen, Age and Body Mass Index on the Biological Composition of Leukocyte Rich Platelet-Rich Plasma: A Prospective, Therapeutic, Cohort Study by Mannava, Sandeep, Whitney, Kaitlyn E., King, Jillian, Kennedy, Mitchell, Klett, Katarina, Dornan, Grant, Chahla, Jorge, Evans, Thos A., Huard, Johnny, LaPrade, Robert F.

“…Objectives: Platelet-rich plasma (PRP) is comprised of several biologically active factors that can stimulate musculoskeletal healing processes. Non-steroidal…”
Get full text