Search Results - "Kleppe, Lene"

Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon by Güralp, Hilal, Skaftnesmo, Kai O., Kjærner-Semb, Erik, Straume, Anne Hege, Kleppe, Lene, Schulz, Rüdiger W., Edvardsen, Rolf B., Wargelius, Anna

“…Genetic introgression of escaped farmed Atlantic salmon ( Salmo salar ) into wild populations is a major environmental concern for the salmon aquaculture…”
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Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation by Edvardsen, Rolf B, Leininger, Sven, Kleppe, Lene, Skaftnesmo, Kai Ove, Wargelius, Anna

“…Understanding the biological function behind key proteins is of great concern in Atlantic salmon, both due to a high commercial importance and an interesting…”
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Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon by Wargelius, Anna, Leininger, Sven, Skaftnesmo, Kai Ove, Kleppe, Lene, Andersson, Eva, Taranger, Geir Lasse, Schulz, Rüdiger W, Edvardsen, Rolf B

“…Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic integrity of wild populations. Using germ cell-free fish in…”
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Transcriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon by Kleppe, Lene, Edvardsen, Rolf Brudvik, Furmanek, Tomasz, Andersson, Eva, Skaftnesmo, Kai Ove, Thyri Segafredo, Frida, Wargelius, Anna

“…Sustainability challenges are currently hampering an increase in salmon production. Using sterile salmon can solve problems with precocious puberty and genetic…”
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Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9-mediated HDR in Atlantic salmon by Straume, Anne Hege, Kjærner-Semb, Erik, Ove Skaftnesmo, Kai, Güralp, Hilal, Kleppe, Lene, Wargelius, Anna, Edvardsen, Rolf Brudvik

“…Precise gene editing such as CRISPR/Cas9-mediated homology directed repair (HDR) can increase our understanding of gene function and improve traits of…”
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Author Correction: Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon by Güralp, Hilal, Skaftnesmo, Kai O., Kjærner‑Semb, Erik, Straume, Anne Hege, Kleppe, Lene, Schulz, Rüdiger W., Edvardsen, Rolf B., Wargelius, Anna

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Heterochiasmy and the establishment of gsdf as a novel sex determining gene in Atlantic halibut by Edvardsen, Rolf Brudvik, Wallerman, Ola, Furmanek, Tomasz, Kleppe, Lene, Jern, Patric, Wallberg, Andreas, Kjærner-Semb, Erik, Mæhle, Stig, Olausson, Sara Karolina, Sundström, Elisabeth, Harboe, Torstein, Mangor-Jensen, Ragnfrid, Møgster, Margareth, Perrichon, Prescilla, Norberg, Birgitta, Rubin, Carl-Johan

“…Atlantic Halibut (Hippoglossus hippoglossus) has a X/Y genetic sex determination system, but the sex determining factor is not known. We produced a…”
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Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies by Crespo, Diego, Skaftnesmo, Kai Ove, Kjærner-Semb, Erik, Yilmaz, Ozlem, Norberg, Birgitta, Olausson, Sara, Vogelsang, Petra, Bogerd, Jan, Kleppe, Lene, Edvardsen, Rolf B, Andersson, Eva, Wargelius, Anna, Hansen, Tom J, Fjelldal, Per Gunnar, Schulz, Rüdiger W

“…Precocious male maturation causes reduced welfare and increased production costs in Atlantic salmon ( ) aquaculture. The pituitary produces and releases…”
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Loss of stra8 Increases Germ Cell Apoptosis but Is Still Compatible With Sperm Production in Atlantic Salmon ( Salmo salar ) by Skaftnesmo, Kai O, Crespo, Diego, Kleppe, Lene, Andersson, Eva, Edvardsen, Rolf B, Norberg, Birgitta, Fjelldal, Per Gunnar, Hansen, Tom J, Schulz, Rüdiger W, Wargelius, Anna

“…Entering meiosis strictly depends on ( ) gene function in mammals. This gene is missing in a number of fish species, including medaka and zebrafish, but is…”
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Maternal 3'UTRs: from egg to onset of zygotic transcription in Atlantic cod by Kleppe, Lene, Edvardsen, Rolf B, Kuhl, Heiner, Malde, Ketil, Furmanek, Tomasz, Drivenes, Oyvind, Reinhardt, Richard, Taranger, Geir L, Wargelius, Anna

“…Zygotic transcription in fish embryos initiates around the time of gastrulation, and all prior development is initiated and controlled by maternally derived…”
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Effects of dietary arachidonic acid on the reproductive physiology of female Atlantic cod (Gadus morhua L.) by Norberg, Birgitta, Kleppe, Lene, Andersson, Eva, Thorsen, Anders, Rosenlund, Grethe, Hamre, Kristin

“…Highlights • Dietary arachidonic acid affected reproductive endocrinology in female cod. • Arachidonic acid had higher accumulation in ovarian tissue than in…”
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Ocean warming shapes embryonic developmental prospects of the next generation in Atlantic cod by Skjærven, Kaja H, Alix, Maud, Kleppe, Lene, Fernandes, Jorge M O, Whatmore, Paul, Nedoluzhko, Artem, Andersson, Eva, Kjesbu, Olav Sigurd

“…Abstract Although early embryonic protein production relies exclusively on maternal molecules such as messenger RNAs (mRNAs) incorporated into ovarian…”
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Loss of Fshr Prevents Testicular Maturation in Atlantic Salmon (Salmo salar L.) by Andersson, Eva, Schulz, Rüdiger W, Almeida, Fernanda, Kleppe, Lene, Skaftnesmo, Kai Ove, Kjærner-Semb, Erik, Crespo, Diego, Fjelldal, Per Gunnar, Hansen, Tom Johnny, Norberg, Birgitta, Edvardsen, Rolf B, Wargelius, Anna

“…Abstract Early puberty poses a significant challenge for male Atlantic salmon in aquaculture due to its negative impact on growth and welfare. The regulation…”
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Loss of bmp15 function in the seasonal spawner Atlantic salmon results in ovulatory failure by Crespo, Diego, Fjelldal, Per Gunnar, Hansen, Tom J., Kjærner‐Semb, Erik, Skaftnesmo, Kai Ove, Thorsen, Anders, Norberg, Birgitta, Edvardsen, Rolf B., Andersson, Eva, Schulz, Rüdiger W., Wargelius, Anna, Kleppe, Lene

“…Bone morphogenetic protein 15 (BMP15) is an oocyte‐specific growth factor important for successful female reproduction in mammals. While mutations in…”
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Gonad specific genes in Atlantic salmon (Salmon salar L.): Characterization of tdrd7-2, dazl-2, piwil1 and tdrd1 genes by Kleppe, Lene, Wargelius, Anna, Johnsen, Hanne, Andersson, Eva, Edvardsen, Rolf B.

“…Atlantic salmon is a commercially important species. Understanding key processes in their life history, such as germ cell development is essential for further…”
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Heterochiasmy and the establishment of gsdf as a novel sex determining gene in Atlantic halibut by Rolf Brudvik Edvardsen, Ola Wallerman, Tomasz Furmanek, Lene Kleppe, Patric Jern, Andreas Wallberg, Erik Kjærner-Semb, Stig Mæhle, Sara Karolina Olausson, Elisabeth Sundström, Torstein Harboe, Ragnfrid Mangor-Jensen, Margareth Møgster, Prescilla Perrichon, Birgitta Norberg, Carl-Johan Rubin

“…Atlantic Halibut (Hippoglossus hippoglossus) has a X/Y genetic sex determination system, but the sex determining factor is not known. We produced a…”
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Global transcriptome analysis identifies regulated transcripts and pathways activated during oogenesis and early embryogenesis in atlantic cod by Kleppe, Lene, Edvardsen, Rolf Brudvik, Furmanek, Tomasz, Taranger, Geir Lasse, Wargelius, Anna

“…SUMMARY The molecular mechanisms underlying oogenesis and maternally controlled embryogenesis in fish are not fully understood, especially in marine species…”
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bmp15l, figla, smc1bl, and larp6l are preferentially expressed in germ cells in Atlantic salmon (Salmo salar L.) by Kleppe, Lene, Edvardsen, Rolf Brudvik, Furmanek, Tomasz, Andersson, Eva, Juanchich, Amélie, Wargelius, Anna

“…SUMMARY Atlantic salmon is a valuable commercial aquaculture species that would benefit economically and environmentally by controlling precocious puberty and…”
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Sex steroid production associated with puberty is absent in germ cell-free salmon by Kleppe, Lene, Andersson, Eva, Skaftnesmo, Kai Ove, Edvardsen, Rolf B., Fjelldal, Per Gunnar, Norberg, Birgitta, Bogerd, Jan, Schulz, Rüdiger W., Wargelius, Anna

“…In all vertebrates studied so far, germ cells are not required for pubertal maturation of the gonadal steroidogenic system, subsequent development of secondary…”
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Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis by Kjærner-Semb, Erik, Ayllon, Fernando, Kleppe, Lene, Sørhus, Elin, Skaftnesmo, Kai, Furmanek, Tomasz, Segafredo, Frida T., Thorsen, Anders, Fjelldal, Per Gunnar, Hansen, Tom, Taranger, Geir Lasse, Andersson, Eva, Schulz, Rüdiger W., Wargelius, Anna, Edvardsen, Rolf B.

“…Vgll3 is linked to age at maturity in Atlantic salmon ( Salmo salar ). However, the molecular mechanisms involving Vgll3 in controlling timing of puberty as…”
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