Search Results - "Klemm, Uwe"

Bioengineered bacterial vesicles as biological nano-heaters for optoacoustic imaging by Gujrati, Vipul, Prakash, Jaya, Malekzadeh-Najafabadi, Jaber, Stiel, Andre, Klemm, Uwe, Mettenleiter, Gabriele, Aichler, Michaela, Walch, Axel, Ntziachristos, Vasilis

“…Advances in genetic engineering have enabled the use of bacterial outer membrane vesicles (OMVs) to deliver vaccines, drugs and immunotherapy agents, as a…”
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Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia by Chumduri, Cindrilla, Gurumurthy, Rajendra Kumar, Berger, Hilmar, Dietrich, Oliver, Kumar, Naveen, Koster, Stefanie, Brinkmann, Volker, Hoffmann, Kirstin, Drabkina, Marina, Arampatzi, Panagiota, Son, Dajung, Klemm, Uwe, Mollenkopf, Hans-Joachim, Herbst, Hermann, Mangler, Mandy, Vogel, Jörg, Saliba, Antoine-Emmanuel, Meyer, Thomas F.

“…The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one…”
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Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging by Mishra, Kanuj, Fuenzalida-Werner, Juan Pablo, Pennacchietti, Francesca, Janowski, Robert, Chmyrov, Andriy, Huang, Yuanhui, Zakian, Christian, Klemm, Uwe, Testa, Ilaria, Niessing, Dierk, Ntziachristos, Vasilis, Stiel, Andre C.

“…Reversibly photo-switchable proteins are essential for many super-resolution fluorescence microscopic and optoacoustic imaging methods. However, they have yet…”
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Phototrophic purple bacteria as optoacoustic in vivo reporters of macrophage activity by Peters, Lena, Weidenfeld, Ina, Klemm, Uwe, Loeschcke, Anita, Weihmann, Robin, Jaeger, Karl-Erich, Drepper, Thomas, Ntziachristos, Vasilis, Stiel, Andre C.

“…Τhe morphology, physiology and immunology, of solid tumors exhibit spatial heterogeneity which complicates our understanding of cancer progression and therapy…”
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Induction of microRNA-155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis by Koch, Manuel, Mollenkopf, Hans-Joachim, Klemm, Uwe, Meyer, Thomas F

“…Helicobacter pylori is a gastric pathogen responsible for a high disease burden worldwide. Deregulated inflammatory responses, possibly involving macrophages,…”
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The miR-221/222 cluster regulates hematopoietic stem cell quiescence and multipotency by suppressing both Fos/AP-1/IEG pathway activation and stress-like differentiation to granulocytes by Jani, Peter K, Petkau, Georg, Kawano, Yohei, Klemm, Uwe, Guerra, Gabriela Maria, Heinz, Gitta Anne, Heinrich, Frederik, Durek, Pawel, Mashreghi, Mir-Farzin, Melchers, Fritz

“…Throughout life, hematopoietic stem cells (HSCs), residing in bone marrow (BM), continuously regenerate erythroid/megakaryocytic, myeloid, and lymphoid cell…”
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A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs by Karlas, Alexander, Berre, Stefano, Couderc, Thérèse, Varjak, Margus, Braun, Peter, Meyer, Michael, Gangneux, Nicolas, Karo-Astover, Liis, Weege, Friderike, Raftery, Martin, Schönrich, Günther, Klemm, Uwe, Wurzlbauer, Anne, Bracher, Franz, Merits, Andres, Meyer, Thomas F., Lecuit, Marc

“…Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide…”
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Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages by Weidenfeld, Ina, Zakian, Christian, Duewell, Peter, Chmyrov, Andriy, Klemm, Uwe, Aguirre, Juan, Ntziachristos, Vasilis, Stiel, Andre C.

“…Macrophages are one of the most functionally-diverse cell types with roles in innate immunity, homeostasis and disease making them attractive targets for…”
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Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice by Huang, Shan, Blutke, Andreas, Feuchtinger, Annette, Klemm, Uwe, Zachariah Tom, Robby, Hofmann, Susanna M, Stiel, Andre C, Ntziachristos, Vasilis

“…The increasing worldwide prevalence of obesity, fatty liver diseases and the emerging understanding of the important roles lipids play in various other…”
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Multifunctional croconaine nanoparticles for efficient optoacoustic imaging of deep tumors and photothermal therapy by Liu, Nian, O’Connor, Patrick, Gujrati, Vipul, Anzenhofer, Pia, Klemm, Uwe, Kleigrewe, Karin, Sattler, Michael, Plettenburg, Oliver, Ntziachristos, Vasilis

“…The proper design of near-infrared light-absorbing agents enables efficient optoacoustic imaging-guided phototherapy. In particular, several croconaine-based…”
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Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors by Liu, Nian, Gujrati, Vipul, Malekzadeh-Najafabadi, Jaber, Werner, Juan Pablo Fuenzalida, Klemm, Uwe, Tang, Longguang, Chen, Zhenyue, Prakash, Jaya, Huang, Yuanhui, Stiel, Andre, Mettenleiter, Gabriele, Aichler, Michaela, Blutke, Andreas, Walch, Axel, Kleigrewe, Karin, Razansky, Daniel, Sattler, Michael, Ntziachristos, Vasilis

“…The CR780RGD-NPs can easily penetrate the blood-brain-barrier and actively target the brain tumor, where the strong optoacoustic generation from CR780RGD-NPs…”
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Alginate beads as a highly versatile test-sample for optoacoustic imaging by Fuenzalida-Werner, Juan Pablo, Mishra, Kanuj, Stankevych, Mariia, Klemm, Uwe, Ntziachristos, Vasilis, Stiel, Andre C.

“…Test-samples are necessary for the development of emerging imaging approaches such as optoacoustics (OA); these can be used to benchmark new labeling agents…”
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Infection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro by Niendorf, Sandra, Klemm, Uwe, Mas Marques, Andreas, Bock, C-Thomas, Höhne, Marina

“…Norovirus infection is the main cause of epidemic non-bacterial gastroenteritis in humans. Although human norovirus (HuNoV) infection is self-limiting, it can…”
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Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif by Geserick, Peter, Kaiser, Frank, Klemm, Uwe, Kaufmann, Stefan H. E., Zerrahn, Jens

“…The regulatory networks governing development and differentiation of hematopoietic cells are incompletely understood. Members of the Schlafen (Slfn) protein…”
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Resolution of Spatial and Temporal Heterogeneity in Bevacizumab-Treated Breast Tumors by Eigenspectra Multispectral Optoacoustic Tomography by Liapis, Evangelos, Klemm, Uwe, Karlas, Angelos, Reber, Josefine, Ntziachristos, Vasilis

“…Understanding temporal and spatial hemodynamic heterogeneity as a function of tumor growth or therapy affects the development of novel therapeutic strategies…”
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Certified Registered Nurse Anesthetists’ (CRNA) Perceived Ease and Usefulness of Video Laryngoscopes for Endotracheal Intubation of Surgical Patients With Difficult Airways by Klemm, Uwe

“…Anesthesia providers frequently encounter patients with difficult airways. The inability to effectively ventilate and oxygenate a patient due to failed…”
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Chemotherapeutic effects on breast tumor hemodynamics revealed by eigenspectra multispectral optoacoustic tomography (eMSOT) by Liapis, Evangelos, Karlas, Angelos, Klemm, Uwe, Ntziachristos, Vasilis

“…Non-invasive monitoring of hemodynamic tumor responses to chemotherapy could provide unique insights into the development of therapeutic resistance and inform…”
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Benchmarking of fluorescence cameras through the use of a composite phantom by Gorpas, Dimitris, Koch, Maximilian, Anastasopoulou, Maria, Klemm, Uwe, Ntziachristos, Vasilis

“…Fluorescence molecular imaging (FMI) has shown potential to detect and delineate cancer during surgery or diagnostic endoscopy. Recent progress on imaging…”
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Multi-Parametric Standardization of Fluorescence Imaging Systems Based on a Composite Phantom by Gorpas, Dimitris, Koch, Maximilian, Anastasopoulou, Maria, Bozhko, Dmitry, Klemm, Uwe, Nieberler, Markus, Ntziachristos, Vasilis

“…Objective: Fluorescence molecular imaging (FMI) has emerged as a promising tool for surgical guidance in oncology, with one of the few remaining challenges…”
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Comprehensive phantom for interventional fluorescence molecular imaging by Anastasopoulou, Maria, Koch, Maximilian, Gorpas, Dimitris, Karlas, Angelos, Klemm, Uwe, Garcia-Allende, Pilar Beatriz, Ntziachristos, Vasilis

“…Fluorescence imaging has been considered for over a half-century as a modality that could assist surgical guidance and visualization. The administration of…”
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