Search Results - "Klemm, Denis"

Leveraging mass detection to simultaneously quantify surfactant content and degradation mode for highly concentrated biopharmaceuticals by Kopf, Robert, Paschen, Christoph, Müller, Lavinia, Kocar, Berk, Wolfring, Martin, Vincent, Mathilde, Klemm, Denis, Bell, Christian, Pinto, Cosimo

“…Non-ionic surfactants are commonly used in parenteral protein formulations and include polysorbate 20, polysorbate 80 and poloxamer188. Recently,…”
Get full text

Fast and Automated Characterization of Antibody Variants with 4D HPLC/MS by Gstöttner, Christoph, Klemm, Denis, Haberger, Markus, Bathke, Anja, Wegele, Harald, Bell, Christian, Kopf, Robert

“…Characterization of unknown monoclonal antibody (mAb) variants is important in order to identify their potential impact on safety, potency, and stability. Ion…”
Get full text

Screening techniques for monitoring the sub-visible particle formation of free fatty acids in biopharmaceuticals by Chen, Wei, Klemm, Denis, Gregoritza, Kathrin, Satya Krishna Kishore, Ravuri, Olaf Stracke, Jan, Wurth, Christine, Pinto, Cosimo, Sancho Oltra, Nuria

“…[Display omitted] Free fatty acid (FFA) particles that originate from the enzymatic hydrolysis of polysorbate (PS) via co-purified host cell proteins generally…”
Get full text

Simultaneous quantification of polysorbate 20 and poloxamer 188 in biopharmaceutical formulations using evaporative light scattering detection by Paschen, Christoph A., Klemm, Denis, Graf, Tobias, Kopf, Robert, Pinto, Cosimo, Müller, Claudia, Bell, Christian H., Pfaff, Janina

“…•Need for alternative surfactants to Polysorbate and Poloxamer 188 to overcome potential risks.•Mix of Polysorbates and Poloxamer 188 as promising approach for…”
Get full text

Controlling of material analysers of the GD-OES type with help of pump-down curves by Klemm, Denis, Hoffmann, Volker, Edelmann, Christian

“…Today, material analysis in industry and research centres is very often performed by the glow-discharge optical emission spectrometry (GD-OES), which allows an…”
Get full text

DC- and RF-GD-OES measurements of adsorbed organic monolayers on copper by Klemm, Denis, Hoffmann, Volker, Wetzig, Klaus, Eckert, Jürgen

“…Our direct current (DC)- and radiofrequency glow discharge optical emission spectroscopy (RF-GD-OES) measurements of adsorbed organic monolayers were inspired…”
Get full text

DC- and RF-GD-OES measurements of adsorbed organic monolayers on copper: Analytical Science in Germany by KLEMM, Denis, HOFFMANN, Volker, WETZIG, Klaus, ECKERT, Jürgen

Get full text

Analysis of interface impurities in electroplated Cu layers by using GD-OES and TOF-SIMS by Klemm, Denis, Stangl, Marcel, Peeva, Anita, Hoffmann, Volker, Wetzig, Klaus, Eckert, Jürgen

“…Electrochemically deposited (ECD) copper layers used as interconnect metallizations exhibit incorporated impurities in the form of H, S, C, O, N, and Cl…”
Get full text

Evaluation of pumpdown curves illustrated for a glow discharge source by Klemm, Denis, Hoffmann, Volker, Edelmann, Christian

“…Evaluation of pumpdown curves illustrated for a glow discharge source In the present state, the GLOW DISCHARGE OPTICAL EMISSION SPECTROMETRY (=GD-OES) is…”
Get full text

Evaluierung von Abpumpkurven am Beispiel einer Glimmentladungsquelle by Klemm, Denis, Hoffmann, Volker, Edelmann, Christian

“…Bei modernen GD‐OES‐Geräten (GD‐OES = Glow Discharge Optical Emission Spectrometry) wird die Analysenzeit (Bruttoanalysezeit: 2 ‐ 5 Minuten) wesentlich durch…”
Get full text

Evaluierung von Abpumpkurven am Beispiel einer Glimmentladungsquelle by Klemm, Denis, Hoffmann, Volker, Edelmann, Christian

Get full text

Scanning force microscopy of two-dimensional structure formation in thin humic acid films by Mertig, Michael, Klemm, Denis, Zänker, Harald, Pompe, Wolfgang

“…Humic acid films have been prepared by spin‐coating on mica substrates and imaged by scanning force microscopy (SFM). The deposited humic acid films exhibit…”
Get full text

Improvement of the Adherence of Thermal Barrier Coatings for Rocket Combustion Chambers by Beyer, S., Klemm, D., Bobeth, M., Pompe, W., Trommer, O., Gawlitza, P.

“…The improvement of the adherence of thermal barrier coatings on a copper material as used in rocket combustion chambers by introducing an additional Al or Ti…”
Get full text

Scanning force microscopy of spin-coated humic acid by Mertig, Michael, Klemm, Denis, Pompe, Wolfgang, Zänker, Harald, Böttger, Manfred

“…We report on investigations of spin‐coated peat humic acid solutions by scanning force microscopy allowing, for the first time, direct imaging of individual…”
Get full text