Search Results - "Klemetti, Miira M"

Genetic Risk Factors and Gene-Lifestyle Interactions in Gestational Diabetes by Jääskeläinen, Tiina, Klemetti, Miira M

“…Paralleling the increasing trends of maternal obesity, gestational diabetes (GDM) has become a global health challenge with significant public health…”
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Increased purchases of prescription medicines in offspring of women with type 1 diabetes: a Finnish register-based cohort study between 1995 and 2018 by Korpijaakko, Cedric A, Eriksson, Johan G, Kautiainen, Hannu, Klemetti, Miira M, Laine, Merja K

“…This study aimed to assess whether exposure to hyperglycemia influences prescription medicine purchases in the offspring of women with type 1 diabetes (exposed…”
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First-trimester HbA1c in relation to plasma glucose concentrations in an oral glucose tolerance test at 12 to 16 weeks’ gestation—a population-based study by Jokelainen, Mervi, Kautiainen, Hannu, Nenonen, Arja, Stach-Lempinen, Beata, Klemetti, Miira M

“…Abstract Background Early-onset GDM often requires pharmacological treatment and is associated with adverse perinatal outcomes, but data is insufficient…”
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Distinct Changes in Placental Ceramide Metabolism Characterize Type 1 and 2 Diabetic Pregnancies with Fetal Macrosomia or Preeclampsia by Klemetti, Miira M, Alahari, Sruthi, Post, Martin, Caniggia, Isabella

“…Disturbances of lipid metabolism are typical in diabetes. Our objective was to characterize and compare placental sphingolipid metabolism in type 1 (T1D) and 2…”
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Fatty liver index in young adult offspring of women with type 1 diabetes by Korpijaakko, Cedric A, Eriksson, Johan G, Kautiainen, Hannu, Klemetti, Miira M, Laine, Merja K

“…Abstract Background Exposure to a hyperglycemic environment during prenatal life may result in an unfavorable metabolic profile later in adulthood. We aimed to…”
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Higher pulse wave velocity in young adult offspring of mothers with type 1 diabetes: a case–control study by Korpijaakko, Cedric A., Eriksson, Mia D., Wasenius, Niko S., Klemetti, Miira M., Teramo, Kari, Kautiainen, Hannu, Eriksson, Johan G., Laine, Merja K.

“…Abstract Background Offspring of mothers with type 1 diabetes have an increased risk for acquiring early onset cardiovascular disease (CVD). Arterial…”
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Late-Pregnancy Fetal Hypoxia Is Associated With Altered Glucose Metabolism and Adiposity in Young Adult Offspring of Women With Type 1 Diabetes by Klemetti, Miira M, Teramo, Kari, Kautiainen, Hannu, Wasenius, Niko, Eriksson, Johan G, Laine, Merja K

“…To investigate associations between exposure to fetal hypoxia and indicators of metabolic health in young adult offspring of women with type 1 diabetes (OT1D)…”
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Lipid profile of circulating placental extracellular vesicles during pregnancy identifies foetal growth restriction risk by Klemetti, Miira M., Pettersson, Ante B. V., Ahmad Khan, Aafaque, Ermini, Leonardo, Porter, Tyler R., Litvack, Michael L., Alahari, Sruthi, Zamudio, Stacy, Illsley, Nicholas P., Röst, Hannes, Post, Martin, Caniggia, Isabella

“…Small‐for‐gestational age (SGA) neonates exhibit increased perinatal morbidity and mortality, and a greater risk of developing chronic diseases in adulthood…”
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Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial by Koivusalo, Saila B, Rönö, Kristiina, Klemetti, Miira M, Roine, Risto P, Lindström, Jaana, Erkkola, Maijaliisa, Kaaja, Risto J, Pöyhönen-Alho, Maritta, Tiitinen, Aila, Huvinen, Emilia, Andersson, Sture, Laivuori, Hannele, Valkama, Anita, Meinilä, Jelena, Kautiainen, Hannu, Eriksson, Johan G, Stach-Lempinen, Beata

“…To assess whether gestational diabetes mellitus (GDM) can be prevented by a moderate lifestyle intervention in pregnant women who are at high risk for the…”
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Obstetric and perinatal outcome in type 1 diabetes patients with diabetic nephropathy during 1988–2011 by Klemetti, Miira M., Laivuori, Hannele, Tikkanen, Minna, Nuutila, Mika, Hiilesmaa, Vilho, Teramo, Kari

“…Aims/hypothesis Our aim was to analyse possible changes in the glycaemic control, BP, markers of renal function, and obstetric and perinatal outcomes of…”
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Robust increases in erythropoietin production by the hypoxic fetus is a response to protect the brain and other vital organs by Teramo, Kari A., Klemetti, Miira M., Widness, John A.

“…Fetal erythropoietin (EPO), in addition to regulating erythropoiesis, has also tissue-protective properties based on its anti-inflammatory, anti-apoptotic,…”
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Analysis of early-pregnancy metabolome in early- and late-onset gestational diabetes reveals distinct associations with maternal overweight by Masalin, Senja, Klåvus, Anton, Rönö, Kristiina, Koistinen, Heikki A., Koistinen, Ville, Kärkkäinen, Olli, Jääskeläinen, Tiina J., Klemetti, Miira M.

“…Aims/hypothesis It is not known whether the early-pregnancy metabolome differs in patients with early- vs late-onset gestational diabetes mellitus (GDM)…”
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Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes by Huvinen, Emilia, Lahti, Jari, Klemetti, Miira M., Bergman, Paula H., Räikkönen, Katri, Orho-Melander, Marju, Laivuori, Hannele, Koivusalo, Saila B.

“…Aims/hypothesis The aim of this study was to assess the interaction between genetic risk and lifestyle intervention on the occurrence of gestational diabetes…”
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Large maternal waist circumference in relation to height is associated with high glucose concentrations in an early‐pregnancy oral glucose tolerance test: A population‐based study by Jokelainen, Mervi, Stach‐Lempinen, Beata, Teramo, Kari, Nenonen, Arja, Kautiainen, Hannu, Klemetti, Miira M.

“…Introduction To explore the role of maternal anthropometric characteristics in early‐pregnancy glycemia, we analyzed the associations and interactions of…”
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Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population by Lokki, A Inkeri, Klemetti, Miira M, Heino, Sanna, Hiltunen, Leena, Heinonen, Seppo, Laivuori, Hannele

“…Pre-eclampsia/eclampsia is a common vascular pregnancy disorder associated with high maternal and infant mortality and morbidity worldwide. The role of Activin…”
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Oral glucose tolerance test results in early pregnancy: A Finnish population-based cohort study by Jokelainen, Mervi, Stach-Lempinen, Beata, Rönö, Kristiina, Nenonen, Arja, Kautiainen, Hannu, Teramo, Kari, Klemetti, Miira M.

“…•Evidence-based criteria for the diagnosis of early gestational diabetes (GDM) are not available.•We performed early-pregnancy oral glucose tolerance testing…”
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Fibronectin and JMJD6 Signature in Circulating Placental Extracellular Vesicles for the Detection of Preeclampsia by Alahari, Sruthi, Ausman, Jonathan, Porter, Tyler, Park, Chanho, Pettersson, Ante B V, Klemetti, Miira M, Zhang, Jianhong, Post, Martin, Caniggia, Isabella

“…Abstract Preeclampsia (PE) is a major obstetric complication that is challenging to predict. Currently, there are limited tools to assess placental…”
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White’s classification and pregnancy outcome in women with type 1 diabetes: a population-based cohort study by Klemetti, Miira M., Laivuori, Hannele, Tikkanen, Minna, Nuutila, Mika, Hiilesmaa, Vilho, Teramo, Kari

“…Aims/hypothesis Our aim was to examine the association of White’s classification with obstetric and perinatal risk factors and outcomes in type 1 diabetic…”
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Macronutrient intake during pregnancy in women with a history of obesity or gestational diabetes and offspring adiposity at 5 years of age by Meinilä, Jelena, Klemetti, Miira M., Huvinen, Emilia, Engberg, Elina, Andersson, Sture, Stach-Lempinen, Beata, Koivusalo, Saila

“…Background/objectives The impact of maternal macronutrient intake during pregnancy on offspring childhood adiposity is unclear. We assessed the associations…”
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Cohort Profile: The Finnish Gestational Diabetes (FinnGeDi) Study by Keikkala, Elina, Mustaniemi, Sanna, Koivunen, Sanna, Kinnunen, Jenni, Viljakainen, Matti, Männisto, Tuija, Ijäs, Hilkka, Pouta, Anneli, Kaaja, Risto, Eriksson, Johan G, Laivuori, Hannele, Gissler, Mika, Erkinheimo, Tiina-Liisa, Keravuo, Ritva, Huttunen, Merja, Metsälä, Jenni, Stach-Lempinen, Beata, Klemetti, Miira M, Tikkanen, Minna, Kajantie, Eero, Vääräsmäki, Marja

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