Search Results - "Kleinsasser, N. H."

Short-term severe thyroid hormone deficiency does not influence sleep parameters by Koehler, C., Ginzkey, C., Kleinsasser, N. H., Hagen, R., Reiners, C., Verburg, F. A.

“…Purpose The influence of short-term severe thyroid hormone deficiency on sleep is currently still unknown. Several studies have demonstrated an effect of…”
Get full text

Bisphosphonate-induced osteonecrosis of the external ear canal: a retrospective study by FROELICH, K, RADELOFF, A, KÖHLER, C, MLYNSKI, R, MÜLLER, J, HAGEN, R, KLEINSASSER, N. H

Get full text

Phthalates demonstrate genotoxicity on human mucosa of the upper aerodigestive tract by Kleinsasser, Norbert H., Kastenbauer, Ernst R., Weissacher, Herbert, Muenzenrieder, Ruth K., Harréus, Ulrich A.

“…Various phthalate compounds are used as softeners and plasticizers in a wide range of plastic materials. There has been a growing concern regarding a possible…”
Get full text

Bisphosphonate-induced osteonecrosis of the external ear canal: a retrospective study by Froelich, K., Radeloff, A., Köhler, C., Mlynski, R., Müller, J., Hagen, R., Kleinsasser, N. H.

“…In 2003, osteonecrosis of the jaw was described as an intraoral complication of bisphosphonate therapy. More recently, cases of avascular necrosis of the hip…”
Get full text

Comparing the genotoxic sensitivities of human peripheral blood lymphocytes and mucosa cells of the upper aerodigestive tract using the Comet assay by Kleinsasser, Norbert H, Wallner, Barbara C, Kastenbauer, Ernst R, Muenzenrieder, Ruth K, Harréus, Ulrich A

“…Carcinogenesis in the upper aerodigestive tract is influenced by multiple factors. Besides tobacco and alcohol consumption, specific pollutants such as…”
Get full text

Altered genotoxicity in mucosal cells of head and neck cancer patients due to environmental pollutants by KLEINSASSER, N. H, WEISSACHER, H, KASTENBAUER, E. R, DIRSCHEDL, P, WALLNER, B. C, HARREUS, U. A

“…The complexity of carcinogenesis in squamous cell cancer (SCC) of the upper aerodigestive tract requires examining environmental risk factors, including…”
Get full text

External trauma to the larynx : classification, diagnosis, therapy by KLEINSASSER, Norbert H, PRIEMER, Fritz G, SCHULZE, Walter, KLEINSASSER, Oskar F

“…In contrast to internal trauma to the larynx caused by endolaryngeal procedures, trauma to the larynx caused by external forces is relatively rare…”
Get full text

Hemoglobin adducts of the human bladder carcinogen o -toluidine after treatment with the local anesthetic prilocaine by Gaber, Kerstin, Harréus, Ulrich A, Matthias, Christoph, Kleinsasser, Norbert H, Richter, Elmar

“…Abstract Prilocaine, a widely used local anesthetic, is metabolized to o -toluidine which is classified as human carcinogen. We aimed to assess the impact of…”
Get full text

Genotoxic effects of myosmine in human lymphocytes and upper aerodigestive tract epithelial cells by Kleinsasser, Norbert H., Wallner, Barbara C., Harréus, Ulrich A., Zwickenpflug, Wolfgang, Richter, Elmar

“…Myosmine, 3-(1-pyrroline-2-yl)pyridine, is an alkaloid found in tobacco plants. Recently, it was also detected in various edibles and staple foods. Whereas…”
Get full text

The use of mini-organ cultures of human upper aerodigestive tract epithelia in ecogenotoxicology by Kleinsasser, Norbert H., Juchhoff, Jutta, Wallner, Barbara C., Bergner, Albrecht, Harréus, Ulrich A., Gamarra, Fernando, Bührlen, Michael, Huber, Rudolf M., Rettenmeier, Albert W.

“…The carcinogenic potential of xenobiotics and possible confounders are often difficult to differentiate in in vivo studies. In contrast, in vitro studies allow…”
Get full text

Mono(2-ethylhexyl)phthalate exhibits genotoxic effects in human lymphocytes and mucosal cells of the upper aerodigestive tract in the comet assay by Kleinsasser, Norbert H, Harréus, Ulrich A, Kastenbauer, Ernst R, Wallner, Barbara C, Sassen, Andrea W, Staudenmaier, Rainer, Rettenmeier, Albert W

“…Phthalic acid esters such as di(2-ethylhexyl)phthalate (DEHP) are widely used as plasticizers in PVC products manufactured for commercial, medical, and…”
Get full text

Sensitivity to DNA-damage induction and chromosomal alterations in mucosa cells from patients with and without cancer of the oropharynx detected by a combination of Comet assay and fluorescence in situ hybridization by Harréus, Ulrich A., Kleinsasser, Norbert H., Zieger, Sabina, Wallner, Barbara, Reiter, Max, Schuller, Paul, Berghaus, Alexander

“…In addition to exogenous risk factors, the development of head and neck cancer is based on genetic alterations and individual sensitivity to mutagens. The…”
Get full text

Effects of nicotine with special consideration given to tumorigenesis in the head and neck region by Semmler, M P, Driemel, O, Staudenmaier, R, Froelich, K, Kleinsasser, N H

“…Tumorigenesis is based on initiation, promotion, and progression, whereas tobacco smoke is a decisive predisposing factor for squamous cell carcinomas of the…”
Get more information

Does nicotine add to the carcinogenic strain of tobacco smoke? by Kleinsasser, N H, Sassen, A W, Semmler, M P, Staudenmaier, R, Harréus, U A, Richter, E

“…It is accepted that nicotine in tobacco smoke causes addiction via nicotinic acetylcholine receptors in the central nervous system. For a long time, the…”
Get full text

Miniorgankulturen humaner nasaler Mukosa : Ein Modell für ökogenotoxikologische Untersuchungen by WALLNER, B. C, HARREUS, U. A, GAMARRA, F, SASSEN, A, KLEINSASSER, N. H

Get full text

Carcinogenic and co-carcinogenic effects of metals and ethanol on human salivary gland tissue by Harréus, U A, Baumeister, P, Wallner, B C, Berghaus, A, Kleinsasser, N H

“…The etiology of malignomas of human salivary glands is examined. Macroscopic, healthy salivary gland tissue from 46 donors was harvested during surgery. Single…”
Get full text

Trägt Nikotin zur Krebsentstehung im oberen Aerodigestivtrakt bei? by KLEINSASSER, N. H, SASSEN, A. W, SEMMLER, M. P, STAUDENMAIER, R, HARREUS, U. A, RICHTER, E

Get full text

Genotoxic effects of vanadium pentoxide on human peripheral lymphocytes and mucosal cells of the upper aerodigestive tract by Kleinsasser, Norbert H, Dirschedl, Peter, Staudenmaier, Rainer, Harréus, Ulrich A, Wallner, Barbara C

“…In addition to tobacco and alcohol consumption, pollutants found in certain industries and in the environment play an important role in carcinogenesis in the…”
Get full text

Karzinogene und kokarzinogene Effekte von Metallen und Ethylalkohol in humanen Speicheldrüsenzellen by HARREUS, U. A, BAUMEISTER, P, WALLNER, B. C, BERGHAUS, A, KLEINSASSER, N. H

Get full text

Effekte von Nikotin unter besonderer Berücksichtigung der Tumorentstehung im Kopf-Hals-Bereich by Semmler, M P, Driemel, O, Staudenmaier, R, Froelich, K, Kleinsasser, N H

“…Die Entstehung von Tumoren ist ein mehrstufiger Prozess, der sich aus Tumorinitiation, Promotion und Progression zusammensetzt. Für Malignome des oberen…”
Get full text