Search Results - "Kleiner, Irena Martin"
-
1
Photochemical Formation of Anthracene Quinone Methide Derivatives
Published in Journal of organic chemistry (16-06-2017)“…Anthrols 2–7 were synthesized and their photochemical reactivity investigated by irradiations in aq CH3OH. Upon excitation with visible light (λ > 400 nm) in…”
Get full text
Journal Article -
2
Polycationic Monomeric and Homodimeric Asymmetric Monomethine Cyanine Dyes with Hydroxypropyl Functionality—Strong Affinity Nucleic Acids Binders
Published in Biomolecules (Basel, Switzerland) (21-07-2021)“…New analogs of the commercial asymmetric monomethine cyanine dyes thiazole orange (TO) and thiazole orange homodimer (TOTO) with hydroxypropyl functionality…”
Get full text
Journal Article -
3
Experimental and Computational Study of the Antioxidative Potential of Novel Nitro and Amino Substituted Benzimidazole/Benzothiazole-2-Carboxamides with Antiproliferative Activity
Published in Antioxidants (12-10-2019)“…We present the synthesis of a range of benzimidazole/benzothiazole-2-carboxamides with a variable number of methoxy and hydroxy groups, substituted with nitro,…”
Get full text
Journal Article -
4
Retracted: Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells
Published in Cell biochemistry and function (01-12-2008)“…The following article from Cell Biochemistry and Function, Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells, by I. Martin‐Kleiner, T. Balog and T…”
Get full text
Journal Article -
5
BORIS in human cancers – A review
Published in European journal of cancer (1990) (01-04-2012)“…Abstract B rother o f the r egulator of the i mprinted s ite (BORIS) or CTCFL is an 11 z inc f inger (ZF) protein, which is considered to be a new oncogene. It…”
Get full text
Journal Article -
6
Signal transduction induced by opioids in immune cells: a review
Published in Neuroimmunomodulation (01-01-2006)“…New data regarding signal transduction triggered by opioid ligands in immune cells are reviewed, and the signal transduction in neuronal cells is documented…”
Get more information
Journal Article -
7
Methionine enkephalin suppresses metabolic activity of a leukemic cell line (NALM-1) and enhances CD10 expression
Published in International immunopharmacology (01-05-2003)“…NALM-1 cells (a cell line derived from human pre-B leukemia) were exposed to the opioid pentapeptide methionine–enkephalin (Met–enkephalin) and/or to…”
Get full text
Journal Article -
8
Copper(II) salicylideneimine complexes revisited: From a novel derivative and extended characterization of two homologues to interaction with BSA and antiproliferative activity
Published in Inorganica Chimica Acta (24-09-2021)“…[Display omitted] •Copper(II) compounds with N-n-alkyl-salicylideneimine ligands were revisited and one novel homologue was prepared.•Three compounds were…”
Get full text
Journal Article -
9
Crown ethers reverse P-glycoprotein-mediated multidrug resistance in cancer cells
Published in Scientific reports (27-09-2018)“…Multidrug resistance (MDR) is a widespread phenomenon exhibited by many cancers and represents a fundamental obstacle for successful cancer treatments. Tumour…”
Get full text
Journal Article -
10
Synthesis and Antiproliferative Activity of Novel 2-Substituted N-Methylated Benzimidazoles and Tetracyclic Benzimidazo [1,2-a]Quinolines
Published in Polycyclic aromatic compounds (14-03-2020)“…In this paper, the synthesis, antiproliferative activity in vitro and structure-activity relationship of N-methylated 2-benzimidazoles related to…”
Get full text
Journal Article -
11
Amino substituted benzimidazo[1,2-a]quinolines: Antiproliferative potency, 3D QSAR study and DNA binding properties
Published in European journal of medicinal chemistry (21-10-2016)“…We describe the synthesis, 3D-derived quantitative structure-activity relationship (QSAR), antiproliferative activity and DNA binding properties of a series of…”
Get full text
Journal Article -
12
Synthesis and Antiproliferative activity in vitro of Amidino Substituted 2-phenylbenzazoles
Published in Croatica Chemica Acta (2019)“…Within this work we describe the synthesis of versatile substituted 2-phenyl benzothiazole 3-10 and 2-phenylbenzimidazole 12-19 derivatives bearing amidino…”
Get full text
Journal Article Paper -
13
Near-Visible Light Generation of a Quinone Methide from 3‑Hydroxymethyl-2-anthrol
Published in Journal of organic chemistry (16-05-2014)“…Excitation of 2-hydroxy-3-(diphenylhydroxymethyl)anthracene (7) to S1 initiates photodehydration, giving the corresponding quinone methide (QM) that was…”
Get full text
Journal Article -
14
Anilides and quinolones with nitrogen-bearing substituents from benzothiophene and thienothiophene series: Synthesis, photochemical synthesis, cytostatic evaluation, 3D-derived QSAR analysis and DNA-binding properties
Published in European journal of medicinal chemistry (01-01-2014)“…A series of new anilides (2a–c, 4–7, 17a–c, 18) and quinolones (3a–b, 8a–b, 9a–b, 10–15, 19) with nitrogen-bearing substituents from benzo[b]thiophene and…”
Get full text
Journal Article -
15
Antibacterial and antiproliferative activity of novel 2-benzimidazolyl- and 2-benzothiazolyl-substituted benzo[b]thieno-2-carboxamides
Published in Molecular diversity (01-08-2018)“…Novel nitro ( 3a–3f )- and amino ( 4a–4f and 5a–5f )-substituted 2-benzimidazolyl and 2-benzothiazolyl benzo[ b ]thieno-2-carboxamides were designed and…”
Get full text
Journal Article -
16
Synthesis and antiproliferative activity of amino-substituted benzimidazo[1,2-a]quinolines as mesylate salts designed by 3D-QSAR analysis
Published in Molecular diversity (01-08-2017)“…An experimental search for new benzimidazole derivatives with enhanced antiproliferative activity was successfully guided by QSAR modelling. Robust 3D-QSAR…”
Get full text
Journal Article -
17
Synthesis, antioxidative and antiproliferative activity of methoxy amidino substituted benzamides and benzimidazoles
Published in Medicinal chemistry research (01-09-2017)“…Within this manuscript the synthesis and potential antioxidative and antiproliferative activity of novel methoxy amidino substituted bezamides 6 – 17 and…”
Get full text
Journal Article -
18
Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis
Published in Cancer letters (01-03-2010)“…Abstract The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a…”
Get full text
Journal Article -
19
Synthesis, cytostatic activity and ADME properties of C-5 substituted and N-acyclic pyrimidine derivatives
Published in Bioorganic & medicinal chemistry letters (01-01-2012)“…The synthesis of 5-alkyl pyrimidine derivatives, 5,6-dihydrofuro[2,3-d]pyrimidines and 5-alkyl N-methoxymethyl pyrimidine derivatives and their cytostatic…”
Get full text
Journal Article -
20
Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine - synthesis, cytostatic, antiviral and antioxidative studies
Published in Journal of enzyme inhibition and medicinal chemistry (01-06-2013)“…A series of novel 1,4-substituted semicarbazides 5a-g with a primaquine moiety bridged by a carbonyl group at position 1 and a cycloalkyl, aryl, benzyloxy or…”
Get more information
Journal Article