Search Results - "Kleiner, DE"

Beta-alanine supplementation enhances judo-related performance in highly-trained athletes by de Andrade Kratz, Caroline, de Salles Painelli, Vitor, de Andrade Nemezio, Kleiner Márcio, da Silva, Rafael Pires, Franchini, Emerson, Zagatto, Alessandro Moura, Gualano, Bruno, Artioli, Guilherme Giannini

“…Abstract Objectives In official judo competitions, athletes usually engage in 5–7 matches in the same day, performing numerous high-intensity efforts…”
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Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis by Stetler-Stevenson, W G, Liotta, L A, Kleiner, Jr, D E

“…Tumor invasion and metastasis formation are major obstacles for successful cancer therapy. Metastasis is a complex multistep process that requires sequential…”
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APECED‐Associated Hepatitis: Clinical, Biochemical, Histological and Treatment Data From a Large, Predominantly American Cohort by Chascsa, David M., Ferré, Elise M. N., Hadjiyannis, Yannis, Alao, Hawwa, Natarajan, Mukil, Quinones, Mariam, Kleiner, David E., Simcox, Thomas L., Chitsaz, Ehsan, Rose, Stacey R., Hallgren, Asa, Kampe, Olle, Marko, Jamie, Ali, Rabab O., Auh, Sungyoung, Koh, Christopher, Belkaid, Yasmine, Lionakis, Michail S., Heller, Theo

“…Background and Aims Autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED), caused by autoimmune regulator (AIRE) mutations, manifests with…”
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Design and validation of a histological scoring system for nonalcoholic fatty liver disease by KLEINER, David E, BRUNT, Elizabeth M, YEH, Matthew, MCCULLOUGH, Arthur J, SANYAL, Arun J, VAN NATTA, Mark, BEHLING, Cynthia, CONTOS, Melissa J, CUMMINGS, Oscar W, FERRELL, Linda D, LIU, Yao-Chang, TORBENSON, Michael S, UNALP-ARIDA, Aynur

“…Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis in the absence of a history of significant alcohol use or other known liver…”
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Long‐term therapy of chronic delta hepatitis with peginterferon alfa by Heller, T., Rotman, Y., Koh, C., Clark, S., Haynes‐Williams, V., Chang, R., McBurney, R., Schmid, P., Albrecht, J., Kleiner, D. E., Ghany, M. G., Liang, T. J., Hoofnagle, J. H.

“…Summary Background Chronic delta hepatitis virus (HDV) infection rapidly progresses to cirrhosis. Treatment with peginterferon for up to 2 years is often…”
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Renal tubular dysfunction during long-term adefovir or tenofovir therapy in chronic hepatitis B by Gara, N., Zhao, X., Collins, M. T., Chong, W. H., Kleiner, D. E., Jake Liang, T., Ghany, M. G., Hoofnagle, J. H.

“…Summary Background Adefovir and tenofovir are nucleotide analogues used as long‐term therapy of chronic hepatitis B. Side effects are few, but prolonged and…”
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Clinical and Histopathologic Features of Fluoroquinolone-Induced Liver Injury by Orman, Eric S, Conjeevaram, Hari S, Vuppalanchi, Raj, Freston, James W, Rochon, James, Kleiner, David E, Hayashi, Paul H

“…Background & Aims Fluoroquinolone-induced liver injury is rare; no prospective studies of well-characterized case series have been published. We studied…”
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Identification of microRNAs specifically expressed in hepatitis C virus‐associated hepatocellular carcinoma by Diaz, Giacomo, Melis, Marta, Tice, Ashley, Kleiner, David E., Mishra, Lopa, Zamboni, Fausto, Farci, Patrizia

“…Although several studies have investigated the association of miRNAs with hepatocellular carcinoma (HCC), the data published so far are not concordant. A…”
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Nodular regenerative hyperplasia in X-linked agammaglobulinemia: An underestimated and severe complication by Nunes-Santos, Cristiane J., Koh, Christopher, Rai, Anjali, Sacco, Keith, Marciano, Beatriz E., Kleiner, David E., Marko, Jamie, Bergerson, Jenna R.E., Stack, Michael, Rivera, Maria M., Constantine, Gregory, Strober, Warren, Uzel, Gulbu, Fuss, Ivan J., Notarangelo, Luigi D., Holland, Steven M., Rosenzweig, Sergio D., Heller, Theo

“…Late-onset complications in X-linked agammaglobulinemia (XLA) are increasingly recognized. Nodular regenerative hyperplasia (NRH) has been reported in primary…”
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Comparative analysis of portal hepatic infiltrating leucocytes in acute drug‐induced liver injury, idiopathic autoimmune and viral hepatitis by Foureau, D. M., Walling, T. L., Maddukuri, V., Anderson, W., Culbreath, K., Kleiner, D. E., Ahrens, W. A., Jacobs, C., Watkins, P. B., Fontana, R. J., Chalasani, N., Talwalkar, J., Lee, W. M., Stolz, A., Serrano, J., Bonkovsky, H. L.

“…Summary Drug‐induced liver injury (DILI) is often caused by innate and adaptive host immune responses. Characterization of inflammatory infiltrates in the…”
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Recent Advances in the Histopathology of Drug-Induced Liver Injury by Kleiner, David E., MD, PhD

“…Abstract Drug-induced liver injury (DILI) is constantly changing as new drugs are approved and as new herbals and dietary supplements (HDS) reach the market…”
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A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis by Promrat, Kittichai, Lutchman, Glen, Uwaifo, Gabriel I., Freedman, Renee J., Soza, Alejandro, Heller, Theo, Doo, Edward, Ghany, Marc, Premkumar, Ahalya, Park, Yoon, Liang, T. Jake, Yanovski, Jack A., Kleiner, David E., Hoofnagle, Jay H.

“…Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease for which there is no known effective therapy. A proportion of patients with NASH…”
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Associations of gender and a proxy of female menopausal status with histological features of drug‐induced liver injury by Suzuki, Ayako, Barnhart, Huiman, Gu, Jiezhun, Bonkovsky, Herbert L., Tillmann, Hans L., Fontana, Robert J., Kleiner, David E.

“…Background & Aim Gender and menopause may contribute to type and severity of drug‐induced liver injury (DILI) by influencing host responses to injury. The aim…”
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Peripheral CD4+CD8+ T cells are differentiated effector memory cells with antiviral functions by Nascimbeni, Michelina, Shin, Eui-Cheol, Chiriboga, Luis, Kleiner, David E., Rehermann, Barbara

“…Although an increased frequency of CD4+CD8+ T cells has been observed in the peripheral blood during viral infections, their role, function, and biologic…”
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Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy by JAVOR, Edward D, GHANY, Marc G, COCHRAN, Elaine K, ORAL, Elif Arioglu, DEPAOLI, Alex M, PREMKUMAR, Ahalya, KLEINER, David E, GORDEN, Phillip

“…Severe lipodystrophy is characterized by diminished adipose tissue and hypoleptinemia, leading to ectopic triglyceride accumulation. In the liver, this is…”
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Higher-order complex formation between the 72-kilodalton type IV collagenase and tissue inhibitor of metalloproteinases-2 by Kleiner, David E, Unsworth, Edward J, Krutzsch, Henry C, Stetler-Stevenson, William G

“…The collagenases are a class of matrix degradative enzymes whose actions are important in physiological and pathological processes. The human 72-kDa type IV…”
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Gastrointestinal Involvement in Chronic Granulomatous Disease by Marciano, Beatriz E, Rosenzweig, Sergio D, Kleiner, David E, Anderson, Victoria L, Darnell, Dirk N, Anaya-O'Brien, Sandra, Hilligoss, Dianne M, Malech, Harry L, Gallin, John I, Holland, Steven M

“…Chronic granulomatous disease (CGD) is a rare disorder of phagocyte oxidative metabolism. In addition to infectious complications, granulomatous lesions often…”
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Long‐term outcome of chronic hepatitis C after sustained virological response to interferon‐based therapy by Koh, C., Heller, T., Haynes‐Williams, V., Hara, K., Zhao, X., Feld, J. J., Kleiner, D. E., Rotman, Y., Ghany, M. G., Liang, T. J., Hoofnagle, J. H.

“…Summary Background Although the short‐term benefits of a sustained virological response (SVR) to interferon‐based therapies of chronic hepatitis C (CHC) are…”
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The liver biopsy in chronic hepatitis C: a view from the other side of the microscope by Kleiner, David E

“…The liver biopsy has long been the gold standard for the evaluation of the state of liver disease in patients with chronic hepatitis C. Although a liver biopsy…”
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Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Campath-1H) by KIRK, Allan D, HALE, Douglas A, MANNON, Roslyn B, KLEINER, David E, HOFFMANN, Steven C, KAMPEN, Robert L, CENDALES, Linda K, TADAKI, Douglas K, HARLAN, David M, SWANSON, S. John

“…Profound T-cell depletion before allotransplantation with gradual posttransplant T-cell repopulation induces a state of donor-specific immune…”
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