Search Results - "Klein Wolterink, Roel G.J"
-
1
Neuroimmune Interactions in Peripheral Organs
Published in Annual review of neuroscience (08-07-2022)“…Interactions between the nervous and immune systems were recognized long ago, but recent studies show that this crosstalk occurs more frequently than was…”
Get full text
Journal Article -
2
Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor
Published in Molecular therapy. Methods & clinical development (12-06-2020)“…Adoptive natural killer (NK) cell therapy is attaining promising clinical outcomes in recent years, but improvements are needed. Genetic modification of NK…”
Get full text
Journal Article -
3
intrathymic crossroads of T and NK cell differentiation
Published in Immunological reviews (01-11-2010)“…T lymphocytes depend on the thymic microenvironment for initiation of the T‐cell developmental program. As the progenitors in the thymus have lost the capacity…”
Get full text
Journal Article -
4
Neuro-mesenchymal units control ILC2 and obesity via a brain–adipose circuit
Published in Nature (London) (16-09-2021)“…Copyright © 2021, The Author(s), under exclusive licence to Springer Nature Limited Signals from sympathetic neurons and immune cells regulate adipocytes and…”
Get full text
Journal Article -
5
Chimeric antigen receptor natural killer (CAR-NK) cell design and engineering for cancer therapy
Published in Journal of hematology and oncology (01-05-2021)“…Due to their efficient recognition and lysis of malignant cells, natural killer (NK) cells are considered as specialized immune cells that can be genetically…”
Get full text
Journal Article -
6
Gata3 drives development of RORγt+ group 3 innate lymphoid cells
Published in The Journal of experimental medicine (10-02-2014)“…Group 3 innate lymphoid cells (ILC3) include IL-22-producing NKp46(+) cells and IL-17A/IL-22-producing CD4(+) lymphoid tissue inducerlike cells that express…”
Get full text
Journal Article -
7
Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5⁺ and IL-13⁺ type 2 innate lymphoid cells
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2013)“…Group 2 innate lymphoid cells (ILC2s; also called nuocytes, innate helper cells, or natural helper cells) provide protective immunity during helminth infection…”
Get full text
Journal Article -
8
NKG2A genetic deletion promotes human primary NK cell anti-tumor responses better than an anti-NKG2A monoclonal antibody
Published in Molecular therapy (07-08-2024)“…Natural killer (NK) cells eliminate infected or cancer cells via their cytotoxic capacity. NKG2A is an inhibitory receptor on NK cells and cancer cells often…”
Get more information
Journal Article -
9
BTK Signaling in B Cell Differentiation and Autoimmunity
Published in Current topics in microbiology and immunology (01-01-2016)“…Since the original identification of Bruton's tyrosine kinase (BTK) as the gene defective in the primary immunodeficiency X-linked agammaglobulinemia (XLA) in…”
Get more information
Journal Article -
10
GATA-3 promotes T-cell specification by repressing B-cell potential in pro–T cells in mice
Published in Blood (07-03-2013)“…Transcription factors orchestrate T-lineage differentiation in the thymus. One critical checkpoint involves Notch1 signaling that instructs T-cell commitment…”
Get full text
Journal Article -
11
Neuroendocrine Cells Take Your Breath Away
Published in Immunity (Cambridge, Mass.) (17-07-2018)“…Pulmonary neuroimmune networks have emerged as important regulators of lung homeostasis. In a recent issue of Science, Sui et al. show that strategically…”
Get full text
Journal Article -
12
Enforced expression of Gata3 in T cells and group 2 innate lymphoid cells increases susceptibility to allergic airway inflammation in mice
Published in The Journal of immunology (1950) (15-02-2014)“…Airway inflammation in allergic asthma reflects a threshold response of the innate immune system, including group 2 innate lymphoid cells (ILC2), followed by…”
Get full text
Journal Article -
13
Influence of Vitamin C on Lymphocytes: An Overview
Published in Antioxidants (10-03-2018)“…Vitamin C or ascorbic acid (AA) is implicated in many biological processes and has been proposed as a supplement for various conditions, including cancer. In…”
Get full text
Journal Article -
14
Type 2 Innate Lymphocytes in Allergic Airway Inflammation
Published in Current allergy and asthma reports (01-06-2013)“…CD4 + T helper-2 (Th2) cells, which produce a unique profile of IL-4, IL-5 and IL-13 pro-inflammatory cytokines, are thought to be central in the orchestration…”
Get full text
Journal Article