Phytotoxic Neocassane Diterpenes from Eragrostis plana

Five new neocassane-like diterpenes (1–5) were isolated from the roots of Eragrostis plana. Their structures were elucidated by spectroscopic data, and the absolute configurations of the representative compounds neocassa-12(17),15-dien-3-one (2) and neocassa-12(13),15-diene-3,14-dione (5) were assig...

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Bibliographic Details
Published in:	Journal of natural products (Washington, D.C.) Vol. 83; no. 12; pp. 3511 - 3518
Main Authors:	Klein Hendges, Ana Paula P, dos Santos, Elaine Fernanda, Teixeira, Sirlei D, Santana, Francielli S, Trezzi, Michelangelo M, Batista, Andrea N. L, Batista, Joao M, de Lima, Vanderlei A, de Assis Marques, Francisco, Maia, Beatriz Helena L. N. Sales
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society and American Society of Pharmacognosy 24-12-2020
Online Access:	Get full text
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Summary:	Five new neocassane-like diterpenes (1–5) were isolated from the roots of Eragrostis plana. Their structures were elucidated by spectroscopic data, and the absolute configurations of the representative compounds neocassa-12(17),15-dien-3-one (2) and neocassa-12(13),15-diene-3,14-dione (5) were assigned by vibrational circular dichroism. The phytotoxic activity of compounds 3, 4, and 5 was evaluated against the germination and growth of Ipomoea grandifolia and Euphorbia heterophylla. Compound 4 exhibited the most potent activity for growth variables, resulting in the smallest radicle length of I. grandifolia and in the smallest aerial part length of E. heterophylla. Compound 5 reduced the germination speed index more effectively than the herbicide glyphosate (Roundup).
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0163-3864 1520-6025
DOI:	10.1021/acs.jnatprod.0c00324