Search Results - "Klein Hazebroek, Marlou"
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Adapting to the Cold: A Role for Endogenous Fibroblast Growth Factor 21 in Thermoregulation?
Published in Frontiers in endocrinology (Lausanne) (02-07-2020)“…Fibroblast growth factor 21 (FGF21) is in biomedical focus as a treatment option for metabolic diseases, given that administration improves metabolism in mice…”
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Early‐Life Exposure to Dietary Large Phospholipid‐Coated Lipid Droplets Improves Markers of Metabolic and Immune Function in Adipose Tissue Later in Life in a Mouse Model
Published in Molecular nutrition & food research (01-01-2024)“…Scope Human milk (HM) is considered optimal nutrition for infants, beneficially programming adult health outcomes including reduced obesity risk. Early life…”
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Obesity-resistance of UCP1-deficient mice associates with sustained FGF21 sensitivity in inguinal adipose tissue
Published in Frontiers in endocrinology (Lausanne) (11-08-2022)“…Metabolic diseases represent the major health burden of our modern society. With the need of novel therapeutic approaches, fibroblast growth factor 21 (FGF21)…”
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Hyperphagia of female UCP1-deficient mice blunts anti-obesity effects of FGF21
Published in Scientific reports (24-06-2023)“…Increasing energy expenditure through uncoupling protein 1 (UCP1) activity in thermogenic adipose tissue is widely investigated to correct diet-induced obesity…”
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Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis
Published in Molecular metabolism (Germany) (01-08-2022)“…Uncoupling protein 1 (UCP1) catalyses mitochondrial proton leak in brown adipose tissue to facilitate nutrient oxidation for heat production, and may combat…”
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Specific Features of the Hypothalamic Leptin Signaling Response to Cold Exposure Are Reflected in Peripheral Blood Mononuclear Cells in Rats and Ferrets
Published in Frontiers in physiology (15-08-2017)“…Cold exposure induces hyperphagia to counteract fat loss related to lipid mobilization and thermogenic activation. The aim of this study was investigate on the…”
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