Search Results - "Klein, Timothy A"

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  1. 1

    Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System by Klein, Timothy A., Grebenc, Dirk W., Shah, Prakhar Y., McArthur, Owen D., Dickson, Brandon H., Surette, Michael G., Kim, Youngchang, Whitney, John C.

    Published in mBio (26-10-2022)
    “…Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial…”
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    Journal Article
  2. 2

    Contact-Dependent Interbacterial Antagonism Mediated by Protein Secretion Machines by Klein, Timothy A., Ahmad, Shehryar, Whitney, John C.

    Published in Trends in microbiology (Regular ed.) (01-05-2020)
    “…To establish and maintain an ecological niche, bacteria employ a wide range of pathways to inhibit the growth of their microbial competitors. Some of these…”
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  3. 3

    Structure of a tripartite protein complex that targets toxins to the type VII secretion system by Klein, Timothy A, Shah, Prakhar Y, Gkragkopoulou, Polyniki, Grebenc, Dirk W, Kim, Youngchang, Whitney, John C

    “…Type VII secretion systems are membrane-embedded nanomachines used by Gram-positive bacteria to export effector proteins from the cytoplasm to the…”
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    Journal Article
  4. 4

    Bacterial type VII secretion: An important player in host‐microbe and microbe‐microbe interactions by Tran, Hiu‐Ki R., Grebenc, Dirk W., Klein, Timothy A., Whitney, John C.

    Published in Molecular microbiology (01-03-2021)
    “…Type VII secretion systems (T7SSs) are poorly understood protein export apparatuses found in mycobacteria and many species of Gram‐positive bacteria. To date,…”
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    Journal Article
  5. 5

    Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin by Klein, Timothy A., Pazos, Manuel, Surette, Michael G., Vollmer, Waldemar, Whitney, John C.

    Published in Journal of molecular biology (19-10-2018)
    “…Gram-positive bacteria deploy the type VII secretion system (T7SS) to facilitate interactions between eukaryotic and prokaryotic cells. In recent work, we…”
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    Journal Article
  6. 6

    Structure of the Extracellular Region of the Bacterial Type VIIb Secretion System Subunit EsaA by Klein, Timothy A., Grebenc, Dirk W., Gandhi, Shil Y., Shah, Vraj S., Kim, Youngchang, Whitney, John C.

    Published in Structure (London) (04-02-2021)
    “…Gram-positive bacteria use type VII secretion systems (T7SSs) to export effector proteins that manipulate the physiology of nearby prokaryotic and eukaryotic…”
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    Journal Article