Search Results - "Klein, Timothy A"
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Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Published in mBio (26-10-2022)“…Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial…”
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Contact-Dependent Interbacterial Antagonism Mediated by Protein Secretion Machines
Published in Trends in microbiology (Regular ed.) (01-05-2020)“…To establish and maintain an ecological niche, bacteria employ a wide range of pathways to inhibit the growth of their microbial competitors. Some of these…”
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Structure of a tripartite protein complex that targets toxins to the type VII secretion system
Published in Proceedings of the National Academy of Sciences - PNAS (16-01-2024)“…Type VII secretion systems are membrane-embedded nanomachines used by Gram-positive bacteria to export effector proteins from the cytoplasm to the…”
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Bacterial type VII secretion: An important player in host‐microbe and microbe‐microbe interactions
Published in Molecular microbiology (01-03-2021)“…Type VII secretion systems (T7SSs) are poorly understood protein export apparatuses found in mycobacteria and many species of Gram‐positive bacteria. To date,…”
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Molecular Basis for Immunity Protein Recognition of a Type VII Secretion System Exported Antibacterial Toxin
Published in Journal of molecular biology (19-10-2018)“…Gram-positive bacteria deploy the type VII secretion system (T7SS) to facilitate interactions between eukaryotic and prokaryotic cells. In recent work, we…”
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Structure of the Extracellular Region of the Bacterial Type VIIb Secretion System Subunit EsaA
Published in Structure (London) (04-02-2021)“…Gram-positive bacteria use type VII secretion systems (T7SSs) to export effector proteins that manipulate the physiology of nearby prokaryotic and eukaryotic…”
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