Search Results - "Klein, Tilmann A"

Learning relative values in the striatum induces violations of normative decision making by Klein, Tilmann A., Ullsperger, Markus, Jocham, Gerhard

“…To decide optimally between available options, organisms need to learn the values associated with these options. Reinforcement learning models offer a powerful…”
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Dopamine-mediated reinforcement learning signals in the striatum and ventromedial prefrontal cortex underlie value-based choices by Jocham, Gerhard, Klein, Tilmann A, Ullsperger, Markus

“…A large body of evidence exists on the role of dopamine in reinforcement learning. Less is known about how dopamine shapes the relative impact of positive and…”
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Error awareness and the insula: links to neurological and psychiatric diseases by Klein, Tilmann A, Ullsperger, Markus, Danielmeier, Claudia

“…Becoming aware of errors that one has committed might be crucial for strategic behavioral and neuronal adjustments to avoid similar errors in the future. This…”
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Cortical beta power reflects decision dynamics and uncovers multiple facets of post-error adaptation by Fischer, Adrian G., Nigbur, Roland, Klein, Tilmann A., Danielmeier, Claudia, Ullsperger, Markus

“…Adapting to errors quickly is essential for survival. Reaction slowing after errors is commonly observed but whether this slowing is adaptive or maladaptive is…”
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Disentangling performance-monitoring signals encoded in feedback-related EEG dynamics by Kirsch, Franziska, Kirschner, Hans, Fischer, Adrian G., Klein, Tilmann A., Ullsperger, Markus

“…•Multiple regression reveals independent contributions to feedback-locked EEG signal.•Factors influencing FRN and P3a/b revealed in a large sample.•Prediction…”
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Genetically Determined Differences in Learning from Errors by Klein, Tilmann A., Neumann, Jane, Reuter, Martin, Hennig, Jürgen, von Cramon, D. Yves, Ullsperger, Markus

“…The role of dopamine in monitoring negative action outcomes and feedback-based learning was tested in a neuroimaging study in humans grouped according to the…”
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Publisher Correction: Learning relative values in the striatum induces violations of normative decision making by Klein, Tilmann A., Ullsperger, Markus, Jocham, Gerhard

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity by Jocham, Gerhard, Klein, Tilmann A, Neumann, Jane, von Cramon, D. Yves, Reuter, Martin, Ullsperger, Markus

“…In humans, presence of an A1 allele of the DRD2/ANKK1-TaqIa polymorphism is associated with reduced expression of dopamine (DA) D(2) receptors in the striatum…”
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Continuous theta-burst stimulation (cTBS) over the lateral prefrontal cortex alters reinforcement learning bias by Ott, Derek V.M., Ullsperger, Markus, Jocham, Gerhard, Neumann, Jane, Klein, Tilmann A.

“…The prefrontal cortex is known to play a key role in higher-order cognitive functions. Recently, we showed that this brain region is active in reinforcement…”
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Rapid feedback processing in human nucleus accumbens and motor thalamus by Schüller, Thomas, Gruendler, Theo O.J., Jocham, Gerhard, Klein, Tilmann A., Timmermann, Lars, Visser-Vandewalle, Veerle, Kuhn, Jens, Ullsperger, Markus

“…The nucleus accumbens (NAcc) and thalamus are integral parts in models of feedback processing. Deep brain stimulation (DBS) has been successfully employed to…”
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Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonism by Jocham, Gerhard, Klein, Tilmann A, Ullsperger, Markus

“…The firing pattern of midbrain dopamine (DA) neurons is well known to reflect reward prediction errors (PEs), the difference between obtained and expected…”
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Comparing the error‐related negativity across groups: The impact of error‐ and trial‐number differences by Fischer, Adrian G., Klein, Tilmann A., Ullsperger, Markus

“…The error‐related negativity (ERN or Ne) is increasingly being investigated as a marker discriminating interindividual factors and moves toward a surrogate…”
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Assessing error awareness without relying on introspective judgment? by Klein, Tilmann A, Ullsperger, Markus, Danielmeier, Claudia

“…Both procedures have disadvantages (Klein et al., 2013). [...]it would be advantageous, if subjective error awareness could be deduced from the subject's brain…”
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Cortical β Power Reflects a Neural Implementation of Decision Boundary Collapse in Speeded Decisions by Kirschner, Hans, Fischer, Adrian G, Danielmeier, Claudia, Klein, Tilmann A, Ullsperger, Markus

“…A prominent account of decision-making assumes that information is accumulated until a fixed response threshold is crossed. However, many decisions require…”
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Editorial for E-Book: error awareness-insights from cognitive neuroscience, psychiatry and neurology by Klein, Tilmann A, Danielmeier, Claudia, Ullsperger, Markus

“…(2012) put forward a more spatially oriented analysis: they used principal component analysis in order to characterize spatial factors contributing to the Pe:…”
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Gender Influences on Brain Responses to Errors and Post-Error Adjustments by Fischer, Adrian G., Danielmeier, Claudia, Villringer, Arno, Klein, Tilmann A., Ullsperger, Markus

“…Sexual dimorphisms have been observed in many species, including humans and extend to the prevalence and presentation of important mental disorders associated…”
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Transdiagnostic inflexible learning dynamics explain deficits in depression and schizophrenia by Kirschner, Hans, Nassar, Matthew R, Fischer, Adrian G, Frodl, Thomas, Meyer-Lotz, Gabriela, Froböse, Sören, Seidenbecher, Stephanie, Klein, Tilmann A, Ullsperger, Markus

“…Deficits in reward learning are core symptoms across many mental disorders. Recent work suggests that such learning impairments arise by a diminished ability…”
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Neural correlates of error awareness by Klein, Tilmann A., Endrass, Tanja, Kathmann, Norbert, Neumann, Jane, von Cramon, D. Yves, Ullsperger, Markus

“…Error processing results in a number of consequences on multiple levels. The posterior frontomedian cortex (pFMC) is involved in performance monitoring and…”
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Unbiased post-error slowing in interference tasks: A confound and a simple solution by Derrfuss, Jan, Danielmeier, Claudia, Klein, Tilmann A., Fischer, Adrian G., Ullsperger, Markus

“…We typically slow down after committing an error, an effect termed post-error slowing (PES). Traditionally, PES has been calculated by subtracting post-correct…”
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Physical Exercise and Spatial Training: A Longitudinal Study of Effects on Cognition, Growth Factors, and Hippocampal Plasticity by Woost, Luise, Bazin, Pierre-Louis, Taubert, Marco, Trampel, Robert, Tardif, Christine L., Garthe, Alexander, Kempermann, Gerd, Renner, Ulrich, Stalla, Günter, Ott, Derek V. M., Rjosk, Viola, Obrig, Hellmuth, Villringer, Arno, Roggenhofer, Elisabeth, Klein, Tilmann A.

“…Physical exercise has been suggested to improve cognitive performance through various neurobiological mechanisms, mediated by growth factors such as BDNF,…”
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