Search Results - "Klein, Sebastian O."

Photoreductive β-aminoalkylation with amino acids affords functionalized γ-aminoketones for nucleoside mimics by Klein, Sebastian O, Baniahmad, Adina A, Jung, Manfred

“…We developed a facile photoreductive and stereoselective β-aminoalkylation of a crowded enone by blue LED light irradiation using a wide variety of α-amino…”
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Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity by Wang, Sheng, Klein, Sebastian O., Urban, Sylvia, Staudt, Maximilian, Barthes, Nicolas P. F., Willmann, Dominica, Bacher, Johannes, Sum, Manuela, Bauer, Helena, Peng, Ling, Rennar, Georg A., Gratzke, Christian, Schüle, Katrin M., Zhang, Lin, Einsle, Oliver, Greschik, Holger, MacLeod, Calum, Thomson, Christopher G., Jung, Manfred, Metzger, Eric, Schüle, Roland

“…Inhibition of epigenetic regulators by small molecules is an attractive strategy for cancer treatment. Recently, we characterised the role of lysine…”
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