Search Results - "Klein, Michael T."

A new approach for studying GPCR dimers: drug-induced inactivation and reactivation to reveal GPCR dimer function in vitro, in primary culture, and in vivo by Teitler, Milt, Klein, Michael T

“…GPCRs are a major family of homologous proteins and are key mediators of the effects of numerous endogenous neurotransmitters, hormones, cytokines, therapeutic…”
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A Hybrid Regression Model for Day-Ahead Energy Price Forecasting by Bissing, Daniel, Klein, Michael T., Chinnathambi, Radhakrishnan Angamuthu, Selvaraj, Daisy Flora, Ranganathan, Prakash

“…Accurate forecast of the hourly spot price of electricity plays a vital role in energy trading decisions. However, due to the complex nature of the power…”
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Approaches and Software Tools for Modeling Lignin Pyrolysis by Hou, Zhen, Bennett, Craig.A, Klein, Michael T, Virk, Preetinder S

“…The integration of the Attribute Reaction Modeling approach with the CompGen and KME kinetic modeling tools is described through the development of a kinetic…”
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Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions by Teitler, Milt, Toohey, Nicole, Knight, Jessica A., Klein, Michael T., Smith, Carol

“…Rationale The h5-HT 7 receptor is subject to inactivation by risperidone and 9-OH-risperidone, apparently through a pseudo-irreversible complex formed between…”
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Catalytic Cracking of Light Crude Oil to Light Olefins and Naphtha over E‑Cat and MFI: Microactivity Test versus Advanced Cracking Evaluation and the Effect of High Reaction Temperature by Al-Khattaf, Sulaiman, Saeed, Mian Rahat, Aitani, Abdullah, Klein, Michael T

“…The catalytic cracking of light paraffinic crude oil with an API gravity of 51° was compared using two laboratory testing techniques, a fixed-bed microactivity…”
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Catalytic Upgrading of Light Naphtha to Gasoline Blending Components: A Mini Review by Aitani, Abdullah, Akhtar, Muhammad Naseem, Al-Khattaf, Sulaiman, Jin, Yaming, Koseoglo, Omer, Klein, Michael T

“…The upgrading of light naphtha (C5–C6 stream) to gasoline blending components has been the subject of intensive research at both academic and industrial…”
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Computer aided kinetic modeling with KMT and KME by Wei, Wei, Bennett, Craig A., Tanaka, Ryuzo, Hou, Gang, Klein, Michael T., Klein, Michael T.

“…The complexity of many chemical and refining reaction systems and the thus-derived tedious and time-consuming process of building the associated kinetic models…”
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Solvent Effects for the Hydrolysis Reaction of Dibenzyl ether in Supercritical Water: A Combined Density Functional Theory and Molecular Dynamics Simulation Study by Alasiri, Hassan, Klein, Michael T

“…The kinetics of the hydrolysis of heavy hydrocarbons in supercritical water were probed using density function theory (DFT) and molecular dynamics (MD)…”
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Molecular-Level Kinetic Modeling of Lube Base Oil Hydroisomerization by Evenepoel, Nicholas, Agarwal, Pratyush, Klein, Michael T

“…A molecular-level kinetic model was constructed for the hydroisomerization/hydrocracking of a hydrotreated deasphalted oil feed. A kinetic network was…”
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Generating Data-Driven Models from Molecular-Level Kinetic Models: A Kinetic Model Speedup Strategy by Agarwal, Pratyush, Klein, Michael T

“…Strategies to reduce the computer time to access the information in molecular-level kinetic models (MLKMs) were evaluated. A triglyceride hydroprocessing MLKM…”
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Attribute-Based Modeling of Resid Structure and Reaction by Campbell, Darin M, Bennett, Craig, Hou, Zhen, Klein, Michael T

“…An attribute-based approach to modeling resid structure and reaction is described. Monte Carlo simulation of feedstock structure casts the modeling problem in…”
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Molecular-Level Kinetic Modeling of a Real Vacuum Gas Oil Hydroprocessing Refinery System by Agarwal, Pratyush, Sahasrabudhe, Mayuresh, Khandalkar, Sumit, Saravanan, Chandra, Klein, Michael T

“…A molecular-level kinetic model was constructed for a vacuum gas oil hydroprocessing unit. The feedstock molecule selection was based on typical arrangements…”
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Density Functional Theory Probe of the Hydrolysis of Heavy Hydrocarbon Structural Moieties in Supercritical Water by Alasiri, Hassan, Klein, Michael T

“…The thermochemistry and kinetics of hydrolysis in supercritical water were probed using density function theory (DFT). Four molecules (propane, dimethyl ether,…”
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Delplot-Compliant Data: Molecular Observables versus Reaction Intermediates by Abo-Ghander, Nabeel S, Klein, Michael T

“…The Delplot analysis for reaction network elucidation involves the use of measured species and their yields as a function of reactant species. Highly reactive…”
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Molecular-Level Kinetic Modeling of Triglyceride Hydroprocessing by Agarwal, Pratyush, Al-Khattaf, Sulaiman S, Klein, Michael T

“…A molecular-level kinetic model was developed for triglyceride hydroprocessing. Triglyceride molecules were defined on the basis of the 8–22 carbon fatty acids…”
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Targeting Selective Activation of M1 for the Treatment of Alzheimer’s Disease: Further Chemical Optimization and Pharmacological Characterization of the M1 Positive Allosteric Modulator ML169 by Tarr, James C, Turlington, Mark L, Reid, Paul R, Utley, Thomas J, Sheffler, Douglas J, Cho, Hyekyung P, Klar, Rebecca, Pancani, Tristano, Klein, Michael T, Bridges, Thomas M, Morrison, Ryan D, Blobaum, Anna L, Xiang, Zixui, Daniels, J. Scott, Niswender, Colleen M, Conn, P. Jeffrey, Wood, Michael R, Lindsley, Craig W

“…The M1 muscarinic acetylcholine receptor is thought to play an important role in memory and cognition, making it a potential target for the treatment of…”
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Molecular-Level Kinetic Model for C12 Continuous Catalytic Reforming by Zhou, Xiang, Hou, Zhen, Wang, Jieguang, Fang, Wei, Ma, Aizeng, Guo, Jinbiao, Klein, Michael T

“…A detailed kinetic model for a continuous catalytic reforming (CCR) process was developed. The model included 447 naphtha molecules (C1–C12) that underwent…”
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Molecule-based modeling of heavy oil by Horton, Scott R., Hou, Zhen, Moreno, Brian M., Bennett, Craig A., Klein, Michael T.

“…A molecular-level kinetics model has been developed for the pyrolysis of heavy residual oil. Resid structure was modeled in terms of three attribute groups：…”
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Influence of Reaction Reversibility on the Interpretation of Delplots of the Parallel-Series Reaction Network by Abo-Ghander, Nabeel S, Klein, Michael T

“…The use of the Delplot analysis to interpret the experimental results from the parallel-series reaction network A → k 1 B → k 3 C ; A → k 2 D under the…”
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A New Extended Structural Parameter Set for Stochastic Molecular Reconstruction: Application to Asphaltenes by Deniz, Celal Utku, Yasar, Muzaffer, Klein, Michael T

“…The modeling of complex hydrocarbon mixtures is a current issue. The presently available analytical techniques are insufficient alone to fully characterize the…”
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