Search Results - "Klein, Julian D. D."

Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence by de Morrée, Antoine, van Velthoven, Cindy T. J., Gan, Qiang, Salvi, Jayesh S., Klein, Julian D. D., Akimenko, Igor, Quarta, Marco, Biressi, Stefano, Rando, Thomas A.

“…Tissue regeneration depends on the timely activation of adult stem cells. In skeletal muscle, the adult stem cells maintain a quiescent state and proliferate…”
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Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function by de Morree, Antoine, Klein, Julian D D, Gan, Qiang, Farup, Jean, Urtasun, Andoni, Kanugovi, Abhijnya, Bilen, Biter, van Velthoven, Cindy T J, Quarta, Marco, Rando, Thomas A

“…Adult stem cells are essential for tissue homeostasis. In skeletal muscle, muscle stem cells (MuSCs) reside in a quiescent state, but little is known about the…”
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Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling by Benjamin, Daniel I., Both, Pieter, Benjamin, Joel S., Nutter, Christopher W., Tan, Jenna H., Kang, Jengmin, Machado, Leo A., Klein, Julian D.D., de Morree, Antoine, Kim, Soochi, Liu, Ling, Dulay, Hunter, Feraboli, Ludovica, Louie, Sharon M., Nomura, Daniel K., Rando, Thomas A.

“…Short-term fasting is beneficial for the regeneration of multiple tissue types. However, the effects of fasting on muscle regeneration are largely unknown…”
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Death-seq identifies regulators of cell death and senolytic therapies by Colville, Alex, Liu, Jie-Yu, Rodriguez-Mateo, Cristina, Thomas, Samantha, Ishak, Heather D., Zhou, Ronghao, Klein, Julian D.D., Morgens, David W., Goshayeshi, Armon, Salvi, Jayesh S., Yao, David, Spees, Kaitlyn, Dixon, Scott J., Liu, Chun, Rhee, June-Wha, Lai, Celine, Wu, Joseph C., Bassik, Michael C., Rando, Thomas A.

“…Selectively ablating damaged cells is an evolving therapeutic approach for age-related disease. Current methods for genome-wide screens to identify genes whose…”
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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging by Baar, Marjolein P., Brandt, Renata M.C., Putavet, Diana A., Klein, Julian D.D., Derks, Kasper W.J., Bourgeois, Benjamin R.M., Stryeck, Sarah, Rijksen, Yvonne, van Willigenburg, Hester, Feijtel, Danny A., van der Pluijm, Ingrid, Essers, Jeroen, van Cappellen, Wiggert A., van IJcken, Wilfred F., Houtsmuller, Adriaan B., Pothof, Joris, de Bruin, Ron W.F., Madl, Tobias, Hoeijmakers, Jan H.J., Campisi, Judith, de Keizer, Peter L.J.

“…The accumulation of irreparable cellular damage restricts healthspan after acute stress or natural aging. Senescent cells are thought to impair tissue…”
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