Search Results - "Klein, Dionne C G"

Ligand-induced conformational changes allosterically activate Toll-like receptor 9 by Latz, Eicke, Golenbock, Douglas T, Verma, Anjali, Visintin, Alberto, Gong, Mei, Sirois, Cherilyn M, Klein, Dionne C G, Monks, Brian G, McKnight, C James, Lamphier, Marc S, Duprex, W Paul, Espevik, Terje

“…Microbial and synthetic DNA rich in CpG dinucleotides stimulates Toll-like receptor 9 (TLR9), whereas DNA lacking CpG either is inert or can inhibit TLR9…”
Get full text

CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation by Klein, Dionne C.G., Skjesol, Astrid, Kers‐Rebel, Esther D., Sherstova, Tatyana, Sporsheim, Bjørnar, Egeberg, Kjartan W., Stokke, Bjørn T., Espevik, Terje, Husebye, Harald

“…Toll‐like receptor 4 (TLR4) is responsible for the immediate response to Gram‐negative bacteria and signals via two main pathways by recruitment of distinct…”
Get full text

A method for measurement of drug sensitivity of myeloma cells co-cultured with bone marrow stromal cells by Misund, Kristine, Baranowska, Katarzyna A, Holien, Toril, Rampa, Christoph, Klein, Dionne C G, Børset, Magne, Waage, Anders, Sundan, Anders

“…The tumor microenvironment can profoundly affect tumor cell survival as well as alter antitumor drug activity. However, conventional anticancer drug screening…”
Get more information

Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy by Klein, Dionne C.G., Latz, Eicke, Espevik, Terje, Stokke, Bjørn T.

“…Immunostimulatory CpG-DNA activates the innate immune system by binding to Toll-like receptor 9. Structurally different CpG-containing oligonucleotides trigger…”
Get full text

The Saccharomyces cerevisiae Fin1 Protein Forms Cell Cycle-Specific Filaments between Spindle Pole Bodies by van Hemert, Martijn J., Gerda E. M. Lamers, Dionne C. G. Klein, Oosterkamp, Tjerk H., Steensma, H. Yde, G. Paul H. van Heusden

“…The FIN1 gene from the yeast Saccharomyces cerevisiae encodes a basic protein with putative coiled-coil regions. Here we show that in large-budded cells a…”
Get full text

Mannan-Binding Lectin: Structure, Oligomerization, and Flexibility Studied by Atomic Force Microscopy by Jensenius, Henriette, Klein, Dionne C.G., van Hecke, Martin, Oosterkamp, Tjerk H., Schmidt, Thomas, Jensenius, Jens C.

“…Mannan-binding lectin (MBL) is the archetypical pathogen recognition molecule of the innate immune defense. Upon binding to microorganisms, reactions leading…”
Get full text

Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein by Klein, Dionne C. G., Øvrebø, Kirsti Marie, Latz, Eicke, Espevik, Terje, Stokke, Bjørn T.

“…The specific interaction between human Toll‐like receptor 9 (TLR9)–ectodomain (ECD)–fusion protein and immunostimulatory CpG–DNA was measured using force…”
Get full text

The Ring Structure and Organization of Light Harvesting 2 Complexes in a Reconstituted Lipid Bilayer, Resolved by Atomic Force Microscopy by Stamouli, Amalia, Kafi, Sidig, Klein, Dionne C.G., Oosterkamp, Tjerk H., Frenken, Joost W.M., Cogdell, Richard J., Aartsma, Thijs J.

“…The main function of the transmembrane light-harvesting complexes in photosynthetic organisms is the absorption of a light quantum and its subsequent rapid…”
Get full text

Covalent Immobilization of Single Proteins on Mica for Molecular Recognition Force Microscopy by Klein, Dionne C. G., Stroh, Cordula M., Jensenius, Henriette, van Es, Maarten, Kamruzzahan, A. S. M., Stamouli, Amalia, Gruber, Hermann J., Oosterkamp, Tjerk H., Hinterdorfer, Peter

“…Tether them! A matrix of proteins that are covalently bound to mica with only one short tether per protein was created in order to fulfil all requirements for…”
Get full text

Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 by Latz, Eicke, Verma, Anjali, Visintin, Alberto, Gong, Mei, Sirois, Cherilyn M, Klein, Dionne C G, Monks, Brian G, McKnight, C James, Lamphier, Marc S, Duprex, W Paul, Espevik, Terje, Golenbock, Douglas T

Get full text

Erratum: Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 by Latz, Eicke, Verma, Anjali, Visintin, Alberto, Gong, Mei, Sirois, Cherilyn M, Klein, Dionne C G, Monks, Brian G, McKnight, C James, Lamphier, Marc S, Duprex, W Paul, Espevik, Terje, Golenbock, Douglas T

Get full text

Single-Molecule Characterization of Microbial Polysaccharides by Moran Anthony P, Brennan Patrick J, Itzstein Mark von, Holst Otto

Get full text