Search Results - "Klein, D."

Molecular and cellular mechanisms of tooth development, homeostasis and repair by Yu, Tingsheng, Klein, Ophir D

“…The tooth provides an excellent system for deciphering the molecular mechanisms of organogenesis, and has thus been of longstanding interest to developmental…”
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Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies by Klein, Roger D., Hultgren, Scott J.

“…Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-threatening. The continued emergence of antibiotic resistance,…”
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Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial by Klein, D. J., Foster, D., Walker, P. M., Bagshaw, S. M., Mekonnen, H., Antonelli, M.

“…Purpose The EUPHRATES trial examined the impact of polymyxin B hemoperfusion (PMX) on mortality in patients with septic shock and endotoxemia, defined as EAA ≥…”
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Is Parkinson's disease a lysosomal disorder? by Klein, Andrés D, Mazzulli, Joseph R

“…Parkinson's disease has long been considered idiopathic, with most cases having no apparent genetic cause. However, Klein and Mazzulli argue that recent data…”
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Probing magnetism in 2D van der Waals crystalline insulators via electron tunneling by Klein, D R, MacNeill, D, Lado, J L, Soriano, D, Navarro-Moratalla, E, Watanabe, K, Taniguchi, T, Manni, S, Canfield, P, Fernández-Rossier, J, Jarillo-Herrero, P

“…Magnetic insulators are a key resource for next-generation spintronic and topological devices. The family of layered metal halides promises varied magnetic…”
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Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria by Klein, Andrés D., Outeiro, Tiago Fleming

“…β-Glucocerebrosidase (GCase) mutations lead to glucosylceramide build-up in the lysosome, impacting α-synuclein aggregation and autophagy. Recently, Baden and…”
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Brain Disorders Due to Lysosomal Dysfunction by Fraldi, Alessandro, Klein, Andrés D, Medina, Diego L, Settembre, Carmine

“…Recent studies of autophagic and lysosomal pathways have significantly changed our understanding of lysosomes; once thought to be simple degradative and…”
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Privileged Scaffolds or Promiscuous Binders: A Comparative Study on Rhodanines and Related Heterocycles in Medicinal Chemistry by Mendgen, Thomas, Steuer, Christian, Klein, Christian D

“…Rhodanines and related five-membered heterocycles with multiple heteroatoms have recently gained a reputation of being unselective compounds that appear as…”
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Usage of Complementary Medicine in Switzerland: Results of the Swiss Health Survey 2012 and Development Since 2007 by Klein, Sabine D, Torchetti, Loredana, Frei-Erb, Martin, Wolf, Ursula

“…Complementary medicine (CM) is popular in Switzerland. Several CM methods (traditional Chinese medicine/acupuncture, homeopathy, anthroposophic medicine,…”
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Invited review: Influence of climatic conditions on the development, performance, and health of calves by Roland, L, Drillich, M, Klein-Jöbstl, D, Iwersen, M

“…The objective of this review is to provide the reader with an overview of thermoregulatory mechanisms and the influence of climatic conditions in different…”
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Coherent single-photon emission from colloidal lead halide perovskite quantum dots by Utzat, Hendrik, Sun, Weiwei, Kaplan, Alexander E K, Krieg, Franziska, Ginterseder, Matthias, Spokoyny, Boris, Klein, Nathan D, Shulenberger, Katherine E, Perkinson, Collin F, Kovalenko, Maksym V, Bawendi, Moungi G

“…Chemically made colloidal semiconductor quantum dots have long been proposed as scalable and color-tunable single emitters in quantum optics, but they have…”
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RIPK3 as a potential therapeutic target for Gaucher's disease by Vitner, Einat B, Salomon, Ran, Farfel-Becker, Tamar, Meshcheriakova, Anna, Ali, Mohammad, Klein, Andrés D, Platt, Frances M, Cox, Timothy M, Futerman, Anthony H

“…Gaucher's disease is a lysosomal storage disease caused by mutations in the glucocerebrosidase gene. Now, Anthony Futerman and his colleagues report that the…”
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Trends in Electronic Cigarette Use Among U.S. Adults: Use is Increasing in Both Smokers and Nonsmokers by McMillen, Robert C., Gottlieb, Mark A., Shaefer, Regina M. Whitmore, Winickoff, Jonathan P., Klein, Jonathan D.

“…We assessed trends in use of electronic cigarettes among U.S. adults, demographic predictors of use, and smoking status of current electronic cigarette users…”
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Marijuana and the Pediatric Population by Dharmapuri, Sadhana, Miller, Kathleen, Klein, Jonathan D.

“…Cannabinoids, the psychoactive compounds in marijuana, are one of the most commonly used substances in the United States. In this review, we summarize the…”
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Biochemistry and Medicinal Chemistry of the Dengue Virus Protease by Nitsche, Christoph, Holloway, Steven, Schirmeister, Tanja, Klein, Christian D.

“…Nitsche et al examine the biochemistry and medicinal chemistry of the dengue virus protease…”
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Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis by Tian, Hua, Biehs, Brian, Chiu, Cecilia, Siebel, Christian W., Wu, Yan, Costa, Mike, de Sauvage, Frederic J., Klein, Ophir D.

“…Proper organ homeostasis requires tight control of adult stem cells and differentiation through the integration of multiple inputs. In the mouse small…”
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Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors by Juuri, Emma, Saito, Kan, Ahtiainen, Laura, Seidel, Kerstin, Tummers, Mark, Hochedlinger, Konrad, Klein, Ophir D., Thesleff, Irma, Michon, Frederic

“…The continuously growing mouse incisor serves as a valuable model to study stem cell regulation during organ renewal. Epithelial stem cells are localized in…”
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Concentrations of trace elements in human milk: Comparisons among women in Argentina, Namibia, Poland, and the United States by Klein, Laura D, Breakey, Alicia A, Scelza, Brooke, Valeggia, Claudia, Jasienska, Grazyna, Hinde, Katie

“…Human milk contains essential micronutrients for growth and development during early life. Environmental pollutants, such as potentially toxic metals, can also…”
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Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche by Nusse, Ysbrand M., Savage, Adam K., Marangoni, Pauline, Rosendahl-Huber, Axel K. M., Landman, Tyler A., de Sauvage, Frederic J., Locksley, Richard M., Klein, Ophir D.

“…Epithelial surfaces form critical barriers to the outside world and are continuously renewed by adult stem cells 1 . Whereas dynamics of epithelial stem cells…”
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Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist by Spaulding, Caitlin N., Klein, Roger D., Ruer, Ségolène, Kau, Andrew L., Schreiber, Henry L., Cusumano, Zachary T., Dodson, Karen W., Pinkner, Jerome S., Fremont, Daved H., Janetka, James W., Remaut, Han, Gordon, Jeffrey I., Hultgren, Scott J.

“…Both F17-like and type 1 pili promote intestinal colonization in mouse colonic crypts, and the high-affinity mannoside M4284 reduces intestinal colonization of…”
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