Search Results - "Klein, C"

COVID-19 is catalyzing the adoption of teleneurology by Klein, Brad C., Busis, Neil A.

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Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis by van Vught, Lonneke A, Klein Klouwenberg, Peter M. C, Spitoni, Cristian, Scicluna, Brendon P, Wiewel, Maryse A, Horn, Janneke, Schultz, Marcus J, Nürnberg, Peter, Bonten, Marc J. M, Cremer, Olaf L, van der Poll, Tom

“…IMPORTANCE: Sepsis is considered to induce immune suppression, leading to increased susceptibility to secondary infections with associated late mortality…”
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Early pregnancy in the mare: old concepts revisited by Klein, C.

“…“Maternal recognition of pregnancy” (MRP) is commonly used to describe the ongoing embryo-maternal communication during early pregnancy that culminates in…”
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Neural Signatures of Value Comparison in Human Cingulate Cortex during Decisions Requiring an Effort-Reward Trade-off by Klein-Flügge, Miriam C, Kennerley, Steven W, Friston, Karl, Bestmann, Sven

“…Integrating costs and benefits is crucial for optimal decision-making. Although much is known about decisions that involve outcome-related costs (e.g., delay,…”
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Medial and orbital frontal cortex in decision-making and flexible behavior by Klein-Flügge, Miriam C., Bongioanni, Alessandro, Rushworth, Matthew F.S.

“…The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of investigations of decision-making, behavioral flexibility, and social…”
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Anomalous Breaking of Scale Invariance in a Two-Dimensional Fermi Gas by Holten, M, Bayha, L, Klein, A C, Murthy, P A, Preiss, P M, Jochim, S

“…The frequency of the breathing mode of a two-dimensional Fermi gas with zero-range interactions in a harmonic confinement is fixed by the scale invariance of…”
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Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation by Lima Giacobbo, Bruno, Doorduin, Janine, Klein, Hans C., Dierckx, Rudi A. J. O., Bromberg, Elke, de Vries, Erik F. J.

“…Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the healthy and diseased brain. As a result, there is a large body of…”
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Xanthones and Cancer: from Natural Sources to Mechanisms of Action by Klein‐Júnior, Luiz C., Campos, Adriana, Niero, Rivaldo, Corrêa, Rogério, Vander Heyden, Yvan, Filho, Valdir Cechinel

“…Xanthones are a class of heterocyclic natural products that have been widely studied for their pharmacological potential. In fact, they have been serving as…”
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Genomic methods in profiling DNA accessibility and factor localization by Klein, David C., Hainer, Sarah J.

“…Recent advancements in next-generation sequencing technologies and accompanying reductions in cost have led to an explosion of techniques to examine DNA…”
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Multiday Soil Moisture Persistence and Atmospheric Predictability Resulting From Sahelian Mesoscale Convective Systems by Taylor, C. M., Klein, C., Harris, B. L.

“…Skill in predicting where damaging convective storms will occur is limited, particularly in the tropics. In principle, near‐surface soil moisture (SM) patterns…”
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Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study by Klein Klouwenberg, Peter M C, Cremer, Olaf L, van Vught, Lonneke A, Ong, David S Y, Frencken, Jos F, Schultz, Marcus J, Bonten, Marc J, van der Poll, Tom

“…A clinical suspicion of infection is mandatory for diagnosing sepsis in patients with a systemic inflammatory response syndrome. Yet, the accuracy of…”
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Electronic Implementation of a Novel Surveillance Paradigm for Ventilator-associated Events: Feasibility and Validation by KLEIN KLOUWENBERG, Peter M. C, VAN MOURIK, Maaike S. M, ONG, David S. Y, HORN, Janneke, SCHULTZ, Marcus J, CREMER, Olaf L, BONTEN, Marc J. M

“…Accurate surveillance of ventilator-associated pneumonia (VAP) is hampered by subjective diagnostic criteria. A novel surveillance paradigm for…”
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Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing by Hall, Catherine N, Klein-Flügge, Miriam C, Howarth, Clare, Attwell, David

“…Neural activity has been suggested to initially trigger ATP production by glycolysis, rather than oxidative phosphorylation, for three reasons: glycolytic…”
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Training induces changes in white-matter architecture by Scholz, Jan, Klein, Miriam C, Behrens, Timothy E J, Johansen-Berg, Heidi

“…Although experience-dependent structural changes have been found in adult gray matter, there is little evidence for such changes in white matter. Using…”
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Computational modelling of social cognition and behaviour—a reinforcement learning primer by Lockwood, Patricia L, Klein-Flügge, Miriam C

“…Abstract Social neuroscience aims to describe the neural systems that underpin social cognition and behaviour. Over the past decade, researchers have begun to…”
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Homage to Dr. Murray Enkin and the complexity of evidence‐based medicine by Klein, Michael C.

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Behavioral modeling of human choices reveals dissociable effects of physical effort and temporal delay on reward devaluation by Klein-Flügge, Miriam C, Kennerley, Steven W, Saraiva, Ana C, Penny, Will D, Bestmann, Sven

“…There has been considerable interest from the fields of biology, economics, psychology, and ecology about how decision costs decrease the value of rewarding…”
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The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes by Beumer, Wouter, Gibney, Sinead M., Drexhage, Roosmarijn C., Pont‐Lezica, Lorena, Doorduin, Janine, Klein, Hans C., Steiner, Johann, Connor, Thomas J., Harkin, Andrew, Versnel, Marjan A., Drexhage, Hemmo A.

“…Review on the key role for activated microglia and monocytes in the pathogenesis of bipolar disorder and schizophrenia. This review describes a key role for…”
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Structural and resting state functional connectivity beyond the cortex by Harrison, Olivia K., Guell, Xavier, Klein-Flügge, Miriam C., Barry, Robert L.

“…•The human brain connectivity literature has been dominated by cortical research.•Subcortical structures are challenging due to lower signal-to-noise…”
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Saturation editing of genomic regions by multiplex homology-directed repair by Findlay, Gregory M., Boyle, Evan A., Hause, Ronald J., Klein, Jason C., Shendure, Jay

“…The authors perform saturation mutagenesis of genomic regions in their native endogenous chromosomal context by using CRISPR/Cas9 RNA-guided cleavage and…”
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