Search Results - "Klein, A. E."

Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set by Klein, E.A., Richards, D., Cohn, A., Tummala, M., Lapham, R., Cosgrove, D., Chung, G., Clement, J., Gao, J., Hunkapiller, N., Jamshidi, A., Kurtzman, K.N., Seiden, M.V., Swanton, C., Liu, M.C.

“…A multi-cancer early detection (MCED) test used to complement existing screening could increase the number of cancers detected through population screening,…”
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Family Caregiving in Bipolar Disorder: Caregiver Consequences, Caregiver Coping Styles, and Caregiver Distress by Goossens, P.J.J., Van Wijngaarden, B., Knoppert-Van Der Klein, E.A.M., Van Achterberg, T.

“…Aims: This study investigated the consequences caregivers of outpatients with bipolar disorder are confronted with, the distress they experience and their…”
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Prostatectomy at high-volume centers improves outcomes and lowers the costs of care for prostate cancer by Barzi, A, Klein, E A, Dorff, T B, Quinn, D I, Sadeghi, S

“…Background: High-volume surgeons with ⩾250 radical prostatectomies provide superior oncological outcomes as evidenced by a lower rate of PSA recurrence (PSAR)…”
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Retroperitoneal laparoscopic radical nephrectomy: the Cleveland clinic experience by Gill, I S, Schweizer, D, Hobart, M G, Sung, G T, Klein, E A, Novick, A C

“…Laparoscopic radical nephrectomy is usually performed by the transperitoneal approach. At our institution the retroperitoneoscopic approach is preferred. We…”
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Self-reported care needs of outpatients with a bipolar disorder in the Netherlands by GOOSSENS, P. J. J., KNOPPERT-VAN DER KLEIN, E. A. M., KROON, H., VAN ACHTERBERG, T.

“…The care needs of patients with a bipolar disorder have not been studied to date. In the present research, the care needs, care received and unmet care needs…”
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Deep androgen receptor suppression in prostate cancer exploits sexually dimorphic renal expression for systemic glucocorticoid exposure by Alyamani, M., Li, J., Patel, M., Taylor, S., Nakamura, F., Berk, M., Przybycin, C., Posadas, E.M., Madan, R.A., Gulley, J.L., Rini, B., Garcia, J.A., Klein, E.A., Sharifi, N.

“…Enzalutamide and apalutamide are potent next-generation androgen receptor (AR) antagonists used in metastatic and non-metastatic prostate cancer. Metabolic,…”
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randomized controlled Alzheimer’s disease prevention trial’s evolution into an exposure trial: The preadvise trial by Kryscio, R. J, Abner, E. L, Schmitt, F. A, Goodman, P. J, Mendiondo, M, Caban-Holt, A, Dennis, B. C, Mathews, M, Klein, E. A, Crowley, J. J

“…OBJECTIVES: To summarize the ongoing Prevention of Alzheimer’s Disease (AD) by Vitamin E and Selenium (PREADViSE) trial as an ancillary study to SELECT (a…”
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Response to W.C. Taylor, and C. Fiala and E.P. Diamandis by Liu, M.C., Oxnard, G.R., Klein, E.A., Swanton, C., Seiden, M.

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The Surgical Learning Curve for Prostate Cancer Control After Radical Prostatectomy by Vickers, Andrew J., Bianco, Fernando J., Serio, Angel M., Eastham, James A., Schrag, Deborah, Klein, Eric A., Reuther, Alwyn M., Kattan, Michael W., Pontes, J. Edson, Scardino, Peter T.

“…Background The learning curve for surgery—i.e., improvement in surgical outcomes with increasing surgeon experience—remains primarily a theoretical concept;…”
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Association between a CYP3A4 Genetic Variant and Clinical Presentation in African-American Prostate Cancer Patients by PARIS, P. L, KUPELIAN, P. A, HALL, J. M, WILLIAMS, T. L, LEVIN, H, KLEIN, E. A, CASEY, G, WITTE, J. S

“…Prostate cancer incidence, clinical presentation, and mortality rates vary among different ethnic groups. A genetic variant of CYP3A4 , a gene involved in the…”
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A simple indentation device for measuring micrometer-scale tissue stiffness by Levental, I, Levental, K R, Klein, E A, Assoian, R, Miller, R T, Wells, R G, Janmey, P A

“…Mechanical properties of cells and extracellular matrices are critical determinants of function in contexts including oncogenic transformation, neuronal…”
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Role of viagra after radical prostatectomy by Zippe, Craig D., Jhaveri, Faiyaaz M., Klein, Eric A., Kedia, Sumita, Pasqualotto, Fabio F., Kedia, Anurag, Agarwal, Ashok, Montague, Drogo K., Lakin, Milton M.

“…Objectives: To determine whether the response to sildenafil citrate (Viagra) in patients with erectile dysfunction after radical prostatectomy was influenced…”
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Biochemical failure does not predict overall survival after radical prostatectomy for localized prostate cancer: 10-year results by Jhaveri, Faiyaaz M, Zippe, Craig D, Klein, Eric A, Kupelian, Patrick A

“…Objectives. To compare rates of overall survival in men with biochemical failure (bF) to those with no bF after radical prostatectomy for localized prostate…”
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SELECT: the Selenium and Vitamin E Cancer Prevention Trial: rationale and design by Klein, E A, Thompson, I M, Lippman, S M, Goodman, P J, Albanes, D, Taylor, P R, Coltman, C

“…Prostate cancer is the commonest non-skin malignancy in the United States and has a substantial mortality rate despite the use of PSA-based screening…”
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Extent of extracapsular extension in localized prostate cancer by Sohayda, Chris, Kupelian, Patrick A, Levin, Howard S, Klein, Eric A

“…Objectives. To measure the radial extent of extracapsular penetration by tumor cells, thereby providing estimates of the margins needed around target volumes…”
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Declining Rates of Extracapsular Extension After Radical Prostatectomy: Evidence for Continued Stage Migration by JHAVERI, F. M, KLEIN, E. A, KUPELIAN, P. A, ZIPPE, C, LEVIN, H. S

“…Prostate-specific antigen (PSA)-based screening is responsible for a profound clinical stage migration in newly detected prostate cancers. Extracapsular…”
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Stage T1-2 prostate cancer: a multivariate analysis of factors affecting biochemical and clinical failures after radical prostatectomy by Kupelian, P A, Katcher, J, Levin, H S, Klein, E A

“…Prostate-specific antigen (PSA) is extensively used in case selection and outcome evaluation after treatment of clinically localized prostate cancer. Careful…”
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Higher than standard radiation doses (> or =72 Gy) with or without androgen deprivation in the treatment of localized prostate cancer by Kupelian, P A, Mohan, D S, Lyons, J, Klein, E A, Reddy, C A

“…To study the effect on biochemical relapse-free survival (bRFS) and clinical disease-free survival of radiation doses delivered to the prostate and…”
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Family history of prostate cancer in patients with localized prostate cancer: an independent predictor of treatment outcome by Kupelian, P A, Kupelian, V A, Witte, J S, Macklis, R, Klein, E A

“…To determine if familial prostate cancer patients have a less favorable prognosis than patients with sporadic prostate cancer after treatment for localized…”
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Importance of high radiation doses (72 Gy or greater) in the treatment of Stage T1-T3 adenocarcinoma of the prostate by Lyons, Janice A, Kupelian, Patrick A, Mohan, Dasarahally S, Reddy, Chandana A, Klein, Eric A

“…Objectives. To analyze the effect of total radiation dose on the outcome of patients treated with external beam radiotherapy for early-stage prostate cancer…”
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