Search Results - "Klein, A."

Cancer progression and the invisible phase of metastatic colonization by Klein, Christoph A.

“…Metastatic dissemination occurs very early in the malignant progression of a cancer but the clinical manifestation of metastases often takes years. In recent…”
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Selection and adaptation during metastatic cancer progression by Klein, Christoph A.

“…Cancer is often regarded as a process of asexual evolution driven by genomic and genetic instability. Mutation, selection and adaptation are by convention…”
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High-flow nasal oxygen vs. standard oxygen therapy for patients undergoing transcatheter aortic valve replacement with conscious sedation: a randomised controlled trial by Scheuermann, S, Tan, A, Govender, P, Mckie, M, Pack, J, Martinez, G, Falter, F, George, S, A Klein, A

“…Minimally invasive surgery is becoming more common and transfemoral transcatheter aortic valve replacement is offered to older patients with multiple…”
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Cell salvage as part of a blood conservation strategy in anaesthesia by Ashworth, A, Klein, A.A.

“…The use of intraoperative cell salvage and autologous blood transfusion has become an important method of blood conservation. The main aim of autologous…”
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Causes of Higher Climate Sensitivity in CMIP6 Models by Zelinka, Mark D., Myers, Timothy A., McCoy, Daniel T., Po‐Chedley, Stephen, Caldwell, Peter M., Ceppi, Paulo, Klein, Stephen A., Taylor, Karl E.

“…Equilibrium climate sensitivity, the global surface temperature response to CO 2 doubling, has been persistently uncertain. Recent consensus places it likely…”
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Critical links between biodiversity and health in wild bee conservation by Parreño, M.A., Alaux, C., Brunet, J.-L., Buydens, L., Filipiak, M., Henry, M., Keller, A., Klein, A.-M., Kuhlmann, M., Leroy, C., Meeus, I., Palmer-Young, E., Piot, N., Requier, F., Ruedenauer, F., Smagghe, G., Stevenson, P.C., Leonhardt, S.D.

“…Wild bee populations are declining due to human activities, such as land use change, which strongly affect the composition and diversity of available plants…”
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Tumor Cell Invasion in Glioblastoma by Vollmann-Zwerenz, Arabel, Leidgens, Verena, Feliciello, Giancarlo, Klein, Christoph A, Hau, Peter

“…Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16 months. Recent research has revealed novel insights into the…”
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Anomalous Breaking of Scale Invariance in a Two-Dimensional Fermi Gas by Holten, M, Bayha, L, Klein, A C, Murthy, P A, Preiss, P M, Jochim, S

“…The frequency of the breathing mode of a two-dimensional Fermi gas with zero-range interactions in a harmonic confinement is fixed by the scale invariance of…”
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Framework models of tumor dormancy from patient-derived observations by Klein, Christoph A

“…Unusually long latency periods between the treatment of primary tumors and metastatic recurrences are commonly thought to prove the existence and relevance of…”
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Drought and salinity stress alters ROS accumulation, water retention, and osmolyte content in sorghum plants by Nxele, X., Klein, A., Ndimba, B.K.

“…Abiotic stresses such as drought and salinity are major environmental factors that influence crop productivity worldwide. These adverse conditions induce…”
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Optimisation of pre‐operative anaemia in patients before elective major surgery – why, who, when and how? by Munting, K. E., Klein, A. A.

“…Summary Anaemia in surgical patients is a common and serious problem; around 40% of patients presenting for major surgery are anaemic. Patients with…”
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Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators by Klein, Mark A., Denu, John M.

“…Sirtuin 6 (SIRT6) is a nuclear NAD+-dependent deacetylase of histone H3 that regulates genome stability and gene expression. However, nonhistone substrates and…”
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Estimated Maximal Safe Dosages of Tumescent Lidocaine by Klein, Jeffrey A., Jeske, Daniel R.

“…BACKGROUND:Tumescent lidocaine anesthesia consists of subcutaneous injection of relatively large volumes (up to 4 L or more) of dilute lidocaine (≤1 g/L) and…”
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Peri‐operative anaesthetic myocardial preconditioning and protection – cellular mechanisms and clinical relevance in cardiac anaesthesia by Kunst, G., Klein, A. A.

“…Summary Preconditioning has been shown to reduce myocardial damage caused by ischaemia–reperfusion injury peri‐operatively. Volatile anaesthetic agents have…”
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Insights from a refined decomposition of cloud feedbacks by Zelinka, Mark D., Zhou, Chen, Klein, Stephen A.

“…Decomposing cloud feedback into components due to changes in several gross cloud properties provides valuable insights into its physical causes. Here we…”
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A European daily high-resolution gridded data set of surface temperature and precipitation for 1950–2006 by Haylock, M. R., Hofstra, N., Klein Tank, A. M. G., Klok, E. J., Jones, P. D., New, M.

“…We present a European land‐only daily high‐resolution gridded data set for precipitation and minimum, maximum, and mean surface temperature for the period…”
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Patient blood management during the COVID–19 pandemic: a narrative review by Baron, D. M., Franchini, M., Goobie, S. M., Javidroozi, M., Klein, A. A., Lasocki, S., Liumbruno, G. M., Muñoz, M., Shander, A., Spahn, D. R., Zacharowski, K., Meybohm, P.

“…Summary As COVID–19 disease escalates globally, optimising patient outcome during this catastrophic healthcare crisis is the number one priority. The…”
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Variation in nectar quality across 34 grassland plant species by Venjakob, C., Ruedenauer, F. A., Klein, A.‐M., Leonhardt, S. D., Ren, Z.‐X.

“…ABSTRACT Floral nectar is considered the most important floral reward for attracting pollinators. It contains large amounts of carbohydrates besides variable…”
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Low-Cloud Feedbacks from Cloud-Controlling Factors: A Review by Klein, Stephen A., Hall, Alex, Norris, Joel R., Pincus, Robert

“…The response to warming of tropical low-level clouds including both marine stratocumulus and trade cumulus is a major source of uncertainty in projections of…”
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Positive tropical marine low-cloud cover feedback inferred from cloud-controlling factors by Qu, Xin, Hall, Alex, Klein, Stephen A., DeAngelis, Anthony M.

“…Differences in simulations of tropical marine low‐cloud cover (LCC) feedback are sources of significant spread in temperature responses of climate models to…”
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