Search Results - "Kleijn, D. P. V."

Carotid Atherosclerotic Plaques Stabilize After Stroke: Insights Into the Natural Process of Atherosclerotic Plaque Stabilization by Peeters, W, Hellings, W E., de Kleijn, D P.V., de Vries, J P.P.M., Moll, F L., Vink, A, Pasterkamp, G

“…Rupture of unstable atherosclerotic plaques is the pathological substrate for acute ischemic events. Underlying cellular and molecular characteristics of…”
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Role of Toll-like receptor 4 in the initiation and progression of atherosclerotic disease by Pasterkamp, G., Van Keulen, J. K., De Kleijn, D. P. V.

“…The family of Toll‐like receptors (TLRs) initiates an innate immune response after recognition of pathogen‐associated molecular patterns (PAMPs). Evidence is…”
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Monocyte toll-like receptor 2 and 4 responses and expression following percutaneous coronary intervention: association with lesion stenosis and fractional flow reserve by Versteeg, D, Hoefer, I E, Schoneveld, A H, de Kleijn, D P V, Busser, E, Strijder, C, Emons, M, Stella, P R, Doevendans, P A, Pasterkamp, G

“…Toll-like receptors (TLRs) are key players in innate immunity and are causally related to arterial occlusive disease and arterial remodelling. The release of…”
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Increased amount of bone marrow-derived smooth muscle-like cells and accelerated atherosclerosis in diabetic apoE-deficient mice by Fledderus, J.O, van Oostrom, O, de Kleijn, D.P.V, den Ouden, K, Penders, A.F, Gremmels, H, de Bree, P, Verhaar, M.C

“…Abstract Aims Atherosclerotic plaque development is accelerated in patients with diabetes. Bone marrow-derived smooth muscle-like cells have been detected in…”
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The Coronary Sinus Reducer; 5-year Dutch experience by Silvis, M. J. M., Dekker, M., Zivelonghi, C., Agostoni, P., Stella, P. R., Doevendans, P. A., de Kleijn, D. P. V., van Kuijk, J. P., Leenders, G. E., Timmers, L.

“…Background Refractory angina is a growing and major health-care problem affecting millions of patients with coronary artery disease worldwide. The Coronary…”
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Identification of genes potentially involved in disease transformation of CML by JANSSEN, J. J. W. M, KLAVER, S. M, WAISFISZ, Q, PASTERKAMP, G, DE KLEIJN, D. P. V, SCHUURHUIS, G. J, OSSENKOPPELE, G. J

“…In patients with chronic myeloid leukemia (CML) who do not reach a (near) complete cytogenetic response, the disease progresses over several years from an…”
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Heart failure with preserved ejection fraction in women: the Dutch Queen of Hearts program by den Ruijter, H., Pasterkamp, G., Rutten, F. H., Lam, C. S. P., Chi, C., Tan, K. H., van Zonneveld, A. J., Spaanderman, M., de Kleijn, D. P. V.

“…Heart failure (HF) poses a heavy burden on patients, their families and society. The syndrome of HF comes in two types: with reduced ejection fraction (HFrEF)…”
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Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness by Schoneveld, A.H, Hoefer, I, Sluijter, J.P.G, Laman, J.D, de Kleijn, D.P.V, Pasterkamp, G

“…Abstract Background Toll like receptors (TLR) have been recognized for their role in atherosclerotic lesion development and progression. Endogenous TLR ligands…”
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The ethnicity-specific association of biomarkers with the angiographic severity of coronary artery disease by Gijsberts, C. M., Seneviratna, A., Bank, I. E. M., den Ruijter, H. M., Asselbergs, F. W., Agostoni, P., Remijn, J. A., Pasterkamp, G., Kiat, H. C., Roest, M., Richards, A. M., Chan, M. Y., de Kleijn, D. P. V., Hoefer, I. E.

“…Background Risk factor burden and clinical characteristics of patients with coronary artery disease (CAD) differ among ethnic groups. We related biomarkers to…”
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Toll-like receptor 2 stimulation induces intimal hyperplasia and atherosclerotic lesion development by SCHONEVELD, A. H, OUDE NIJHUIS, M. M, VAN MIDDELAAR, B, LAMAN, J. D, DE KLEIJN, D. P. V, PASTERKAMP, G

“…Toll like receptors (Tlr) are essential in activation of the innate immune system. We recently described that peptidoglycan, an exogenous Tlr2 specific ligand,…”
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Activation of the innate immune system in atherosclerotic disease by Oude Nijhuis, M M, van Keulen, J K, Pasterkamp, G, Quax, P H, de Kleijn, D P V

“…Innate immunity is the first line of defence against invading micro-organisms. The family of Toll-like receptors (TLRs) recognizes pathogen-associated…”
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Carotid atherosclerotic plaque characteristics are associated with microembolization during carotid endarterectomy and procedural outcome by VERHOEVEN, B. A. N, DE VRIES, J. P. P. M, PASTERKAMP, G, ACKERSTAFF, R. G. A, SCHONEVELD, A. H, VELEMA, E, DE KLEIJN, D. P. V, MOLL, F. L

“…During carotid endarterectomy (CEA), microemboli may occur, resulting in perioperative adverse cerebral events. The objective of the present study was to…”
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Modulation of collagen turnover in cardiovascular disease by Rodriguez-Feo, J A, Sluijter, J P G, de Kleijn, D P V, Pasterkamp, G

“…Collagen fibers are the most abundant components of the extracellular matrix in arteries and myocardium. Disturbances in the collagen turnover (synthesis and…”
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Rapid, arteriovenous graft failure due to intimal hyperplasia: a porcine, bilateral, carotid arteriovenous graft model by Rotmans, J.I, Velema, E, Verhagen, H.J.M, Blankensteijn, J.D, Kastelein, J.J.P, de Kleijn, D.P.V, Yo, M, Pasterkamp, G, Stroes, E.S.G

“…The loss of patency constitutes the major complication of arteriovenous (AV) polytetrafluoroethylene hemodialysis grafts. In most cases, this graft failure is…”
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Plasma extracellular vesicle protein content for diagnosis and prognosis of global cardiovascular disease by Wang, J. W., Gijsberts, C. M., Seneviratna, A., de Hoog, V. C., Vrijenhoek, J. E. P., Schoneveld, A. H., Chan, M. Y., Lam, C. S. P., Richards, A. M., Lee, C. N., Mosterd, A., Sze, S. K., Timmers, L., Lim, S. K., Pasterkamp, G., de Kleijn, D. P. V.

“…Cardiovascular disease is a major public health problem worldwide. Its growing burden is particularly ominous in Asia, due to increasing rates of major risk…”
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Predictive Risk Factors for Restenosis after Remote Superficial Femoral Artery Endarterectomy by Derksen, W.J.M, Gisbertz, S.S, Hellings, W.E, Vink, A, de Kleijn, D.P.V, de Vries, J.-P.P.M, Moll, F.L, Pasterkamp, G

“…Abstract Objectives Restenosis following remote superficial femoral artery endarterectomy (RSFAE) remains a challenging problem. The determinants predicting…”
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Acute‐phase protein haptoglobin is a cell migration factor involved in arterial restructuring by Kleijn, D. P. V., Smeets, M. B., Kemmeren, P. P. C. W., Lim, S. K., Middelaar, B. J., Velema, E., Schoneveld, A., Pasterkamp, G., Borst, C.

“…ABSTRACT Collagen turnover and cell migration are fundamental aspects of arterial restructuring. To identify mRNAs involved in blood flow‐induced arterial…”
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Arterial remodeling in atherosclerosis, restenosis and after alteration of blood flow : potential mechanisms and clinical implications by PASTERKAMP, G, DE KLEIJN, D. P. V, BORST, C

“…Arterial remodeling is currently being recognized as an important determinant in vascular pathology in which narrowing of the lumen is the predominant feature…”
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Cloning and Expression of Two Crustacean Hyperglycemic‐hormone mRNAs in the Eyestalk of the Crayfish Orconectes limosus by Kleijn, Dominique P. V., Janssen, Karel P. C., Martens, Gerard J. M., Herp, Francois

“…Crustacean hyperglycemic hormone (CHH) is a multifunctional neurohormone produced in the eyestalk of crustaceans and is primarily involved in the regulation of…”
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Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients by van Leeuwen, Fred W., Dominique P. V. de Kleijn, van den Hurk, Helma H., Neubauer, Andrea, Marc A. F. Sonnemans, Sluijs, Jacqueline A., Köycü, Soner, Ravindra D. J. Ramdjielal, Salehi, Ahmad, Gerard J. M. Martens, Grosveld, Frank G., J. Peter H. Burbach, Hol, Elly M.

“…The cerebral cortex of Alzheimer's and Down syndrome patients is characterized by the presence of protein deposits in neurofibrillary tangles, neuritic…”
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