Search Results - "Kleerebezem, Michiel"
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Exopolysaccharides produced by lactic acid bacteria: from health-promoting benefits to stress tolerance mechanisms
Published in Applied microbiology and biotechnology (01-05-2016)“…A wide range of lactic acid bacteria (LAB) is able to produce capsular or extracellular polysaccharides, with various chemical compositions and properties…”
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Can probiotics modulate human disease by impacting intestinal barrier function?
Published in British journal of nutrition (14-01-2017)“…Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is balanced to maximise absorptive capacity, while maintaining…”
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The small intestine microbiota, nutritional modulation and relevance for health
Published in Current opinion in biotechnology (01-04-2015)“…Graphical abstract…”
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Assessing the Impact of Diet on the Mucosa-Adhered Microbiome in Piglets Using Comparative Analysis of Rectal Swabs and Colon Content
Published in Frontiers in microbiology (22-02-2022)“…Previously, we demonstrated that rectal swabs provide a legitimate alternative to faecal sampling for the assessment of the intestinal microbiota in young…”
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Stress Physiology of Lactic Acid Bacteria
Published in Microbiology and molecular biology reviews (01-09-2016)“…Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms. The stress physiology of LAB has been studied in depth for over 2…”
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Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2015)“…Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits…”
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10 years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis
Published in Applied microbiology and biotechnology (01-10-2005)“…Lactococcus lactis is a Gram-positive lactic acid bacterium that, in addition to its traditional use in food fermentations, is increasingly used in modern…”
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The impact of probiotics and prebiotics on the immune system
Published in Nature reviews. Immunology (01-10-2012)“…Here, Nature Reviews Immunology asks four experts to share their thoughts on the ability of probiotics and prebiotics to modulate the immune system and…”
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Nomadic lifestyle of Lactobacillus plantarum revealed by comparative genomics of 54 strains isolated from different habitats
Published in Environmental microbiology (01-12-2016)“…Summary The ability of bacteria to adapt to diverse environmental conditions is well‐known. The process of bacterial adaptation to a niche has been linked to…”
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Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model
Published in The ISME Journal (01-05-2013)“…The human gut is colonized by a complex microbiota with multiple benefits. Although the surface-attached, mucosal microbiota has a unique composition and…”
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The lactococcal ICE-ome encodes a repertoire of exchangeable traits with potential industrial relevance
Published in BMC genomics (30-07-2024)“…Dairy industries apply selected lactococcal strains and mixed cultures to produce diverse fermented products with distinctive flavor and texture properties…”
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The Possible Link Between Manufacturing and Probiotic Efficacy; a Molecular Point of View on Bifidobacterium
Published in Frontiers in microbiology (24-12-2021)“…Probiotics for food or supplement use have been studied in numerous clinical trials, addressing a broad variety of diseases, and conditions. However,…”
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Colonizing Microbes, IL-10 and IL-22: Keeping the Peace at the Mucosal Surface
Published in Frontiers in microbiology (17-09-2021)“…Our world is filled with microbes. Each multicellular organism has developed ways to interact with this microbial environment. Microbes do not always pose a…”
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Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier
Published in American journal of physiology: Gastrointestinal and liver physiology (01-06-2010)“…Lactobacillus plantarum, a commensal bacterium of humans, has been proposed to enhance the intestinal barrier, which is compromised in a number of intestinal…”
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Lactic Acid Bacteria for Delivery of Endogenous or Engineered Therapeutic Molecules
Published in Frontiers in microbiology (03-08-2018)“…Food-grade lactic acid bacteria (LAB) are considered suitable vehicles for the production and/or delivery of health promoting or therapeutic, bioactive…”
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Probiotic and Gut Lactobacilli and Bifidobacteria: Molecular Approaches to Study Diversity and Activity
Published in Annual review of microbiology (01-01-2009)“…Lactobacilli and bifidobacteria have traditionally been recognized as potential health-promoting microbes in the human gastrointestinal tract, which is clearly…”
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Microbiota conservation and BMI signatures in adult monozygotic twins
Published in The ISME Journal (01-04-2013)“…The human gastrointestinal (GI) tract microbiota acts like a virtual organ and is suggested to be of great importance in human energy balance and weight…”
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The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates
Published in The ISME Journal (01-07-2012)“…The human gastrointestinal tract (GI tract) harbors a complex community of microbes. The microbiota composition varies between different locations in the GI…”
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Phenotypic and genetic characterization of differential galacto-oligosaccharide utilization in Lactobacillus plantarum
Published in Scientific reports (10-12-2020)“…Several Lactobacillus plantarum strains are marketed as probiotics for their potential health benefits. Prebiotics, e.g., galacto-oligosaccharides (GOS), have…”
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Immunomodulatory properties of Streptococcus and Veillonella isolates from the human small intestine microbiota
Published in PloS one (05-12-2014)“…The human small intestine is a key site for interactions between the intestinal microbiota and the mucosal immune system. Here we investigated the…”
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