Search Results - "Kleber, Herbert D."

Imaging Dopamine Transmission in Cocaine Dependence: Link Between Neurochemistry and Response to Treatment by Martinez, Diana, Carpenter, Kenneth M, Liu, Fei, Slifstein, Mark, Broft, Allegra, Friedman, Alessandra Calvo, Kumar, Dileep, Van Heertum, Ronald, Kleber, Herbert D, Nunes, Edward

“…Objective:Previous research has shown that dopamine signaling in the limbic striatum is crucial for selecting adaptive, motivated behavior and that disrupted…”
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Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations by Smith, Shannon M., Dart, Richard C., Katz, Nathaniel P., Paillard, Florence, Adams, Edgar H., Comer, Sandra D., Degroot, Aldemar, Edwards, Robert R., Haddox, J. David, Jaffe, Jerome H., Jones, Christopher M., Kleber, Herbert D., Kopecky, Ernest A., Markman, John D., Montoya, Ivan D., O’Brien, Charles, Roland, Carl L., Stanton, Marsha, Strain, Eric C., Vorsanger, Gary, Wasan, Ajay D., Weiss, Roger D., Turk, Dennis C., Dworkin, Robert H.

“…Terminology related to prescription drug misuse and abuse is inconsistently defined. An expert panel developed consensus classifications and definitions for…”
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Anhedonia After a Selective Bilateral Lesion of the Globus Pallidus by Miller, Jeffrey M., Vorel, Stanislav R., Tranguch, Anthony J., Kenny, Edward T., Mazzoni, Pietro, van Gorp, Wilfred G., Kleber, Herbert D.

“…In conclusion, this case suggests an association between bilateral lesions of the globus pallidus and a syndrome of anhedonia, loss of drug cravings, and…”
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Methadone Maintenance 4 Decades Later : Thousands of Lives Saved But Still Controversial by KLEBER, Herbert D

“…Kleber talks about the contoversial methadone maintenance treatment (MMT). Forty years after the last maintenance clinics closed, the 1965 article by Dole and…”
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Older, Less Regulated Medical Marijuana Programs Have Much Greater Enrollment Rates Than Newer 'Medicalized' Programs by Williams, Arthur Robin, Olfson, Mark, Kim, June H, Martins, Silvia S, Kleber, Herbert D

“…Twenty-three states and the District of Columbia have passed laws implementing medical marijuana programs. The nineteen programs that were in operation as of…”
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Use of Dronabinol for Cannabis Dependence: Two Case Reports and Review by Levin, Frances R., Kleber, Herbert D.

“…Marijuana is the most commonly used illicit drug in the United States and throughout the world. Despite this, the number of laboratory studies that have…”
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Pharmacologic treatments for opioid dependence: detoxification and maintenance options by Kleber, Herbert D.

“…While opioid dependence has more treatment agents available than other abused drugs, none are curative. They can, however, markedly diminish withdrawal…”
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The successful return of psychedelics to psychiatry by Kleber, Herbert D

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Physicians and Medical Marijuana by Kleber, Herbert D., Dupont, Robert L.

“…Psychiatrists may be asked by patients for referrals for medical marijuana under legislation in a number of states. There is no clinical scientific literature…”
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Lower Level of Endogenous Dopamine in Patients With Cocaine Dependence: Findings From PET Imaging of D2/ D3 Receptors Following Acute Dopamine Depletion by MARTINEZ, Diana, GREENE, Kaitlin, BROFT, Allegra, KUMAR, Dileep, FEI LIU, NARENDRAN, Rajesh, SLIFSTEIN, Mark, VAN HEERTUM, Ronald, KLEBER, Herbert D

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Minding the brain: the role of pharmacotherapy in substance-use disorder treatment by Elias, Dakwar, Kleber, Herbert D.

“…With its medicalization as a brain-based disease, addiction has come to be regarded as amenable to biomedical treatment approaches, most commonly…”
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Dopamine Type 2/3 Receptor Availability in the Striatum and Social Status in Human Volunteers by Martinez, Diana, Orlowska, Daria, Narendran, Rajesh, Slifstein, Mark, Liu, Fei, Kumar, Dileep, Broft, Allegra, Van Heertum, Ronald, Kleber, Herbert D

“…Background Previous positron emission tomography (PET) imaging studies in nonhuman primates have shown that striatal dopamine type 2/3 (D2/3 ) receptors…”
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Naltrexone-facilitated discontinuation of buprenorphine by Dakwar, Elias, Kleber, Herbert D

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Drug Dependence, a Chronic Medical Illness: Implications for Treatment, Insurance, and Outcomes Evaluation by McLellan, A. Thomas, Lewis, David C, O'Brien, Charles P, Kleber, Herbert D

“…The effects of drug dependence on social systems has helped shape the generally held view that drug dependence is primarily a social problem, not a health…”
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Abuse liability of intravenous buprenorphine/naloxone and buprenorphine alone in buprenorphine-maintained intravenous heroin abusers by Comer, Sandra D., Sullivan, Maria A., Vosburg, Suzanne K., Manubay, Jeanne, Amass, Leslie, Cooper, Ziva D., Saccone, Phillip, Kleber, Herbert D.

“…ABSTRACT Background  Sublingual buprenorphine is an effective maintenance treatment for opioid dependence, yet intravenous buprenorphine misuse occurs. A…”
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Dopamine D1 Receptors in Cocaine Dependence Measured with PET and the Choice to Self-Administer Cocaine by Martinez, Diana, Slifstein, Mark, Narendran, Rajesh, Foltin, Richard W, Broft, Allegra, Hwang, Dah-Ren, Perez, Audrey, Abi-Dargham, Anissa, Fischman, Marian W, Kleber, Herbert D, Laruelle, Marc

“…The goal of this study was to determine D(1) receptor availability in human cocaine-dependent (CD) subjects and matched healthy controls (HCs). In addition,…”
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Cocaine dependence and D2 receptor availability in the functional subdivisions of the striatum: Relationship with cocaine-seeking behavior by MARTINEZ, Diana, BROFT, Allegra, FISCHMAN, Marian W, LARUELLE, Marc, FOLTIN, Richard W, SLIFSTEIN, Mark, HWANG, Dah-Ren, YIYUN HUANG, PEREZ, Audrey, FRANKEL, W. Gordon, COOPER, Thomas, KLEBER, Herbert D

“…Striatal dopamine D2 receptors have been implicated in the neurobiology of cocaine addiction. Previous imaging studies showed reduced striatal D2 receptor…”
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Response to Grant et al. Letter by Kleber, Herbert D., DuPont, Robert L.

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Methadone Maintenance 4 Decades Later by Kleber, Herbert D

“…Twenty-two male patients, addicted to heroin 9.5 years (median), were stabilized using oral methadone hydrochloride and then observed for approximately 1 to 15…”
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Absence of stress dysregulation predicts cocaine and mood outcomes in a study of mirtazapine for depressed cocaine-dependent patients by Raby, Wilfrid N, Dylan, Brion, Glass, Andrew, Pavlikova, Martina, Nunes, Edward V, Kleber, Herbert D

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