Search Results - "Klavinskis, Linda S."

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  1. 1

    Rationale for targeting complement in COVID‐19 by Polycarpou, Anastasia, Howard, Mark, Farrar, Conrad A, Greenlaw, Roseanna, Fanelli, Giorgia, Wallis, Russell, Klavinskis, Linda S, Sacks, Steven

    Published in EMBO molecular medicine (07-08-2020)
    “…A novel coronavirus, SARS‐CoV‐2, has recently emerged in China and spread internationally, posing a health emergency to the global community. COVID‐19 caused…”
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    TCR contact residue hydrophobicity is a hallmark of immunogenic CD8⁺ T cell epitopes by Chowell, Diego, Krishna, Sri, Becker, Pablo D., Cocita, Clément, Shu, Jack, Tan, Xuefang, Greenberg, Philip D., Klavinskis, Linda S., Blattman, Joseph N., Anderson, Karen S.

    “…Despite the availability of major histocompatibility complex (MHC)-binding peptide prediction algorithms, the development of T-cell vaccines against pathogen…”
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    A timely update of global COVID-19 vaccine development by Klavinskis, Linda S., Liu, Margaret A., Lu, Shan

    Published in Emerging microbes & infections (01-01-2020)
    “…This commentary provides an overview and links to presentations of a recent virtual congress series organized by the International Society for Vaccines (ISV)…”
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    Bacillus subtilis spores: A novel microparticle adjuvant which can instruct a balanced Th1 and Th2 immune response to specific antigen by Barnes, Andrew G. C., Cerovic, Vuk, Hobson, Philip S., Klavinskis, LindaS.

    Published in European Journal of Immunology (01-06-2007)
    “…There is a current need for safe, cheap, and effective vaccine adjuvants, to combine with sub‐unit antigens to enhance their immunogenicity. In this study we…”
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    The human intestinal IgA response; burning questions by Spencer, Jo, Klavinskis, Linda S, Fraser, Louise D

    Published in Frontiers in immunology (01-01-2012)
    “…The title of this special topic invites us to identify areas in the field of IgA biology that are uncertain or in need of clarification. The inductive phase of…”
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    A distinct subset of intestinal dendritic cells responds selectively to oral TLR7/8 stimulation by Yrlid, Ulf, Cerovic, Vuk, Milling, Simon, Jenkins, Christopher D., Klavinskis, LindaS., MacPherson, G. Gordon

    Published in European Journal of Immunology (01-10-2006)
    “…The intestinal innate immune system continually interacts with commensal bacteria, thus oral vaccines should induce extra/alternative activation of DC,…”
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    Hyporesponsiveness of Intestinal Dendritic Cells to TLR Stimulation Is Limited to TLR4 by Cerovic, Vuk, Jenkins, Christopher D, Barnes, Andrew G. C, Milling, Simon W. F, MacPherson, G. Gordon, Klavinskis, Linda S

    Published in The Journal of immunology (1950) (15-02-2009)
    “…Dendritic cells (DCs) are crucial to intestinal immune regulation because of their roles in inducing protective immunity against pathogens while maintaining…”
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    Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses by Soderquest, Katrina, Walzer, Thierry, Zafirova, Biljana, Klavinskis, Linda S, Polić, Bojan, Vivier, Eric, Lord, Graham M, Martín-Fontecha, Alfonso

    Published in The Journal of immunology (1950) (15-03-2011)
    “…It is uncertain whether NK cells modulate T cell memory differentiation. By using a genetic model that allows the selective depletion of NK cells, we show in…”
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    Skin vaccination with live virus vectored microneedle arrays induce long lived CD8+ T cell memory by Becker, Pablo D, Hervouet, Catherine, Mason, Gavin M, Kwon, Sung-Yun, Klavinskis, Linda S

    Published in Vaccine (08-09-2015)
    “…Abstract A simple dissolvable microneedle array (MA) platform has emerged as a promising technology for vaccine delivery, due to needle-free injection with a…”
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    Acquisition of MHC:peptide complexes by dendritic cells contributes to the generation of antiviral CD8+ T cell immunity in vivo by Smyth, Lesley A, Hervouet, Catherine, Hayday, Thomas, Becker, Pablo D, Ellis, Richard, Lechler, Robert I, Lombardi, Giovanna, Klavinskis, Linda S

    Published in The Journal of immunology (1950) (01-09-2012)
    “…There is an increasing body of evidence suggesting that the transfer of preformed MHC class I:peptide complexes between a virus-infected cell and an uninfected…”
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    Plasmacytoid Dendritic Cells Do Not Migrate in Intestinal or Hepatic Lymph by Yrlid, Ulf, Cerovic, Vuk, Milling, Simon, Jenkins, Christopher D, Zhang, Jiquan, Crocker, Paul R, Klavinskis, Linda S, MacPherson, G. Gordon

    Published in Journal of Immunology (01-11-2006)
    “…Plasmacytoid dendritic cells (pDCs) recognize pathogen-associated molecules, particularly viral, and represent an important mechanism in innate defense. They…”
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    Intranasal Immunization with Plasmid DNA-Lipid Complexes Elicits Mucosal Immunity in the Female Genital and Rectal Tracts by Klavinskis, Linda S, Barnfield, Christina, Gao, Liquan, Parker, Suezanne

    Published in The Journal of immunology (1950) (01-01-1999)
    “…The development of vaccines against pathogens transmitted across the genito-rectal mucosa that effectively stimulate both secretory IgA Abs and cytotoxic T…”
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    Mucosal immunization with DNA vaccines by Hobson, Philip, Barnfield, Christina, Barnes, Andrew, Klavinskis, Linda S

    Published in Methods (San Diego, Calif.) (01-11-2003)
    “…DNA vaccines represent a new approach to the control of infectious disease. Both cellular and humoral immune responses are induced without the attendant…”
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    Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope by Klavinskis, L S, Whitton, J L, Joly, E, Oldstone, M B

    Published in Virology (New York, N.Y.) (01-10-1990)
    “…The outcome of infection by lymphocytic choriomeningitis virus (LCMV) is determined largely by the cytotoxic T lymphocyte (CTL) response of the host. In H-2b…”
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    Immune modulation of collagen‐induced arthritis by intranasal cytokine gene delivery: A model for the therapy of rheumatoid arthritis by Woods, Andrew M., Thompson, Stephen J., Wooley, Paul H., Panayi, Gabriel, Klavinskis, Linda S.

    Published in Arthritis and rheumatism (01-12-2005)
    “…Objective To develop a passively targeted, patient‐compliant, intranasal interleukin‐10 (IL‐10) gene therapy delivery system and to investigate its therapeutic…”
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    Recent developments in molecular therapeutic approaches for rheumatoid arthritis by Woods, Andrew, Hobson, Philip, Klavinskis, Linda S

    Published in Current opinion in molecular therapeutics (01-08-2004)
    “…Rheumatoid arthritis is a debilitating systemic autoimmune disease characterized by chronic synovial inflammation, which results in the progressive destruction…”
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    Mucosal immunization with DNA-liposome complexes by Klavinskis, Linda S., Gao, Liquan, Barnfield, Christina, Lehner, Thomas, Parker, Suezanne

    Published in Vaccine (01-06-1997)
    “…The mucosal surfaces represent the primary site for transmission of several viruses including HIV. To prevent mucosal transmission and dissemination to the…”
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