Search Results - "Klaude, Maria"
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Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients
Published in The American journal of clinical nutrition (01-12-2013)“…Background: In cancer cachexia, muscle depletion is related to morbidity and mortality. Muscle-wasting mechanisms in cancer patients are not fully…”
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2
Variability in Skeletal Muscle Protein Synthesis Rates in Critically Ill Patients
Published in Nutrients (01-09-2022)“…(1) Background: Muscle protein synthesis in critically ill patients is, on average, normal despite dramatic muscle loss, but the variation is much larger than…”
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3
Repeated quantitative measurements of De Novo synthesis of albumin and fibrinogen
Published in PloS one (28-03-2017)“…The possibility of using two different isotopomers, for the incorporation of isotopically labeled amino acids, was explored to enable longitudinal studies of…”
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4
Lactate kinetics and mitochondrial respiration in skeletal muscle of healthy humans under influence of adrenaline
Published in Clinical science (1979) (01-08-2015)“…Plasma lactate is widely used as a biomarker in critical illness. The aims of the present study were to elucidate the usefulness of a three-compartment model…”
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5
A tracer bolus method for investigating glutamine kinetics in humans
Published in PloS one (08-05-2014)“…Glutamine transport between tissues is important for the outcome of critically ill patients. Investigation of glutamine kinetics is, therefore, necessary to…”
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6
Amino acid metabolism in leg muscle after an endotoxin injection in healthy volunteers
Published in American journal of physiology: endocrinology and metabolism (01-02-2005)“…Decreased plasma amino acid concentrations and increased net release of amino acids from skeletal muscle, especially for glutamine, are common features in…”
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7
Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis
Published in Clinical science (1979) (01-02-2012)“…Muscle wasting negatively affects morbidity and mortality in critically ill patients. This progressive wasting is accompanied by, in general, a normal muscle…”
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8
Whole body protein turnover in critically ill patients with multiple organ failure
Published in Clinical nutrition (Edinburgh, Scotland) (01-02-2015)“…Summary Background & aims To evaluate the effect of nutrition therapy on protein turnover in critically ill patients isotopically labeled amino acids can be…”
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9
Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients123
Published in The American journal of clinical nutrition (01-12-2013)“…In cancer cachexia, muscle depletion is related to morbidity and mortality. Muscle-wasting mechanisms in cancer patients are not fully understood. We…”
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10
The comet assay : mechanisms and technical considerations
Published in Mutation research (12-06-1996)“…The comet assay is frequently used to measure DNA damage in individual cells. In order to better understand the mechanisms behind the technique, we have…”
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11
Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis
Published in Clinical science (1979) (01-07-2007)“…Patients with sepsis in the ICU (intensive care unit) are characterized by skeletal muscle wasting. This leads to muscle dysfunction that also influences the…”
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12
Protein metabolism in leg muscle following an endotoxin injection in healthy volunteers
Published in Clinical science (1979) (2010)“…The human endotoxin model has been used to study the early phase of sepsis. The aim of the present study was to assess leg muscle protein kinetics after an…”
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13
Synthesis rates of total liver protein and albumin are both increased in patients with an acute inflammatory response
Published in Clinical science (1979) (01-01-2006)“…The general perception that catabolism and inflammation are associated with a high synthesis rate of total liver protein and a low albumin synthesis rate has…”
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14
An assay of microsomal membrane-associated proteasomes demonstrates increased proteolytic activity in skeletal muscle of intensive care unit patients
Published in Clinical nutrition (Edinburgh, Scotland) (01-04-2005)“…Background & Aims: Muscle wasting during critical illness is generally believed to be an increase in muscle protein degradation mediated by the proteasome…”
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15
Enhanced in vivo protein synthesis in circulating immune cells of ICU patients
Published in Journal of clinical immunology (01-11-2007)“…Insufficient function of the immune system contributes to a poor prognosis in intensive care unit (ICU) patients. However, the immune system function is not…”
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16
Determination of in vivo protein synthesis in human palatine tonsil
Published in Clinical science (1979) (01-02-2005)“…The palatine tonsils are constantly exposed to ingested or inhaled antigens which, in turn, lead to a permanent activation of tonsillar immune cells, even in a…”
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17
Novel Chinese hamster ultraviolet-sensitive mutants for excision repair form complementation groups 9 and 10
Published in Cancer research (Chicago, Ill.) (01-08-1991)“…In this paper we demonstrate that the mutants CHO7PV and CHO4PV isolated by us from the CHO-K1 prol- cell line represent two new complementation groups of…”
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18
Methionine-cysteine deficiency and alkylation of DNA in liver, kidney and lung of mice administered dimethylnitrosamine
Published in Biochemical pharmacology (15-10-1985)“…The effect of methionine-cysteine deficiency on the methylation of DNA purines by dimethylnitrosamine metabolites was studied in subadult and adult mice. In…”
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19
Effect of protein diet on age-dependent methylation of liver nuclear components of mice administered N-nitrosodimethylamine
Published in JNCI : Journal of the National Cancer Institute (01-10-1984)“…Protein diets deficient or enriched in DL-methionine were studied for the effect of methylation of nuclear components in subadult and adult outbred albino male…”
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20
Non-random effect on RNA synthesis in liver chromatin by administration of dimethylnitrosamine to mice
Published in Archives of toxicology (01-11-1983)“…The effect of dimethylnitrosamine on functional activities of liver chromatin was studied in mice. After a single dose of dimethylnitrosamine injected i.v. (25…”
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