Search Results - "Klaude, M"
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Contractile protein breakdown in human leg skeletal muscle as estimated by [ 2H 3]-3-methylhistidine: A new method
Published in Metabolism, clinical and experimental (01-08-2004)“…3-Methylhistidine urinary excretion and net balances across the leg or forearm have been used as markers of contractile protein breakdown in muscle tissue…”
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OP032 INCREASED LYSOSOMAL ACTIVITY IN SKELETAL MUSCLE IS ASSOCIATED WITH BODY WEIGHT LOSS IN PATIENTS WITH CANCER
Published in Clinical nutrition. Supplements (01-09-2012)Get full text
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3
Longitudinal pattern of glutamine/glutamate balance across the leg in long-stay intensive care unit patients
Published in Clinical nutrition (Edinburgh, Scotland) (01-12-2002)“…Background & Aims: Progressive muscle wasting is a characteristic feature of patients treated at the intensive care unit (ICU). As a consequence, endogenous…”
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4
Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis
Published in Clinical science (1979) (01-02-2012)“…Muscle wasting negatively affects morbidity and mortality in critically ill patients. This progressive wasting is accompanied by, in general, a normal muscle…”
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5
Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients
Published in The American journal of clinical nutrition (01-12-2013)“…Background: In cancer cachexia, muscle depletion is related to morbidity and mortality. Muscle-wasting mechanisms in cancer patients are not fully…”
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6
Whole body protein turnover in critically ill patients with multiple organ failure
Published in Clinical nutrition (Edinburgh, Scotland) (01-02-2015)“…Summary Background & aims To evaluate the effect of nutrition therapy on protein turnover in critically ill patients isotopically labeled amino acids can be…”
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Variability in Skeletal Muscle Protein Synthesis Rates in Critically Ill Patients
Published in Nutrients (01-09-2022)“…(1) Background: Muscle protein synthesis in critically ill patients is, on average, normal despite dramatic muscle loss, but the variation is much larger than…”
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Repeated quantitative measurements of De Novo synthesis of albumin and fibrinogen
Published in PloS one (28-03-2017)“…The possibility of using two different isotopomers, for the incorporation of isotopically labeled amino acids, was explored to enable longitudinal studies of…”
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Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis
Published in Clinical science (1979) (01-07-2007)“…Patients with sepsis in the ICU (intensive care unit) are characterized by skeletal muscle wasting. This leads to muscle dysfunction that also influences the…”
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Lactate kinetics and mitochondrial respiration in skeletal muscle of healthy humans under influence of adrenaline
Published in Clinical science (1979) (01-08-2015)“…Plasma lactate is widely used as a biomarker in critical illness. The aims of the present study were to elucidate the usefulness of a three-compartment model…”
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11
A tracer bolus method for investigating glutamine kinetics in humans
Published in PloS one (08-05-2014)“…Glutamine transport between tissues is important for the outcome of critically ill patients. Investigation of glutamine kinetics is, therefore, necessary to…”
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12
Protein metabolism in leg muscle following an endotoxin injection in healthy volunteers
Published in Clinical science (1979) (2010)“…The human endotoxin model has been used to study the early phase of sepsis. The aim of the present study was to assess leg muscle protein kinetics after an…”
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13
DNA damage and repair after low doses of UV-C radiation; comparable rates of repair in rodent and human cells
Published in International journal of radiation biology (1995)“…The UV endonuclease assay for cyclobutane pyrimidine dimers in the DNA of UV-C-irradiated mammalian cells has been modified by replacing alkaline sucrose…”
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14
Synthesis rates of myosin and actin in skeletal muscle of critically ill patients
Published in Intensive care medicine experimental (01-10-2015)“…Issue Title: ESICM LIVES 2015…”
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15
Synthesis rates of total liver protein and albumin are both increased in patients with an acute inflammatory response
Published in Clinical science (1979) (01-01-2006)“…The general perception that catabolism and inflammation are associated with a high synthesis rate of total liver protein and a low albumin synthesis rate has…”
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16
Amino acid metabolism in leg muscle after an endotoxin injection in healthy volunteers
Published in American journal of physiology: endocrinology and metabolism (01-02-2005)“…Decreased plasma amino acid concentrations and increased net release of amino acids from skeletal muscle, especially for glutamine, are common features in…”
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An assay of microsomal membrane-associated proteasomes demonstrates increased proteolytic activity in skeletal muscle of intensive care unit patients
Published in Clinical nutrition (Edinburgh, Scotland) (01-04-2005)“…Background & Aims: Muscle wasting during critical illness is generally believed to be an increase in muscle protein degradation mediated by the proteasome…”
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18
Diet- and age-dependent modulation of O6-methylguanine-DNA methyltransferase levels in mouse tissues
Published in IARC scientific publications (1987)“…Methylation of guanine in the O6 position by N-nitrosodimethylamine is higher in liver DNA of mice fed a diet restricted in essential amino acids than in…”
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WHOLE BODY PROTEIN TURNOVER IN MECHANICALLY VENTILATED ICU PATIENTS
Published in INTENSIVE CARE MEDICINE (2012)Get full text
Conference Proceeding -
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OMEGA-3 FATTY ACIDS DOES NOT BLUNT IMMUNE RESPONSE OR INFLAMATORY RESPONSE TO AN ENDOTOXIN CHALLENGE IN HEALTHY VOLUNTEERS
Published in INTENSIVE CARE MEDICINE (2011)Get full text
Conference Proceeding