Search Results - "Klatte, Derk C. F."
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Aspects and outcomes of surveillance for individuals at high-risk of pancreatic cancer
Published in Familial cancer (01-08-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths and is associated with a poor prognosis. The majority of these cancers are…”
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Hereditary pancreatic cancer
Published in Baillière's best practice & research. Clinical gastroenterology (01-06-2022)“…Pancreatic cancer is one of the deadliest malignancies. Therefore, there is an urgent need to detect pancreatic cancer in an earlier stage to improve outcomes…”
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Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up
Published in Journal of clinical oncology (01-10-2022)“…Pancreatic cancer surveillance in high-risk individuals may lead to detection of pancreatic ductal adenocarcinoma (PDAC) at an earlier stage and with improved…”
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Surveillance for Pancreatic Cancer in High-Risk Individuals Leads to Improved Outcomes: A Propensity Score-Matched Analysis
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2023)“…Recent pancreatic cancer surveillance programs of high-risk individuals have reported improved outcomes. This study assessed to what extent outcomes of…”
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Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2017)“…Abstract Background & Aims Proton pump inhibitors (PPI) have been associated with acute kidney injury (AKI) and recent studies suggest that they may be…”
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Temporal Trends in Body Composition and Metabolic Markers Prior to Diagnosis of Pancreatic Ductal Adenocarcinoma
Published in Clinical gastroenterology and hepatology (01-09-2024)“…Changes in body composition and metabolic factors may serve as biomarkers for the early detection of pancreatic ductal adenocarcinoma (PDAC). The aim of this…”
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Surgical outcomes after pancreatic surgery in patients with a germline CDKN2A/p16 pathogenic variant under surveillance
Published in British journal of surgery (03-01-2024)Get full text
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Psychosocial issues of individuals undergoing surveillance for increased risk of melanoma and pancreatic cancer due to a germline CDKN2A variant: A focus group study
Published in Journal of genetic counseling (01-10-2024)“…Individuals with a germline CDKN2A pathogenic variant (PV) are at high risk of developing melanoma and pancreatic cancer and are therefore offered…”
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Pancreatic cancer surveillance: Risk stratification of individuals with a germline CDKN2A pathogenic variant
Published in United European gastroenterology journal (07-11-2024)“…Individuals carrying a germline CDKN2A pathogenic variant (PV) are at a high risk of developing pancreatic ductal adenocarcinoma. Risk stratification could…”
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Utilization and Outcomes of Multigene Panel Testing in Patients With Pancreatic Ductal Adenocarcinoma
Published in JCO oncology practice (01-08-2024)“…Guidelines recommend germline genetic testing (GT) for patients with pancreatic ductal adenocarcinoma (PDAC). This study aims to evaluate the utilization and…”
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Identification of individuals at high-risk for pancreatic cancer using a digital patient-input tool combining family cancer history screening and new-onset diabetes
Published in Preventive medicine reports (01-02-2023)“…Capturing family history might be a valuable tool for identification of individuals at increased risk of pancreatic cancer, which would allow enrollment into…”
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Large-scale multi-center CT and MRI segmentation of pancreas with deep learning
Published in Medical image analysis (01-01-2025)“…Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based…”
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Multimodal Pancreatic Cancer Detection Using Methylated DNA Biomarkers in Pancreatic Juice and Plasma CA 19-9: A Prospective Multicenter Study
Published in Clinical gastroenterology and hepatology (28-10-2024)“…In previous studies, methylated DNA markers (MDMs) have been identified in pancreatic juice (PJ) for detecting pancreatic ductal adenocarcinoma (PDAC). In this…”
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Large-Scale Multi-Center CT and MRI Segmentation of Pancreas with Deep Learning
Published 20-05-2024“…Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based…”
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