Search Results - "Klassen, Martin"

Online coupling of size exclusion chromatography to capillary-enhanced Raman spectroscopy for the identification of protein classes in hemolyzed blood serum by Thissen, Jana, Klassen, Martin D., Hacker, Michael C., Breitkreutz, Jörg, Teutenberg, Thorsten, Fischer, Björn

“…The analysis of serum for biomarkers is a standard method in clinical diagnosis and health assessment. The application of Raman spectroscopy to probe…”
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Universal properties of pseudoscalar mediators in dark matter extensions of 2HDMs by Bauer, Martin, Klassen, Martin, Tenorth, Valentin

“…A bstract We discuss universal signals of consistent models of pseudoscalar mediators for collider searches for Dark Matter. Keeping only the degrees of…”
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Online Coupling of Size Exclusion Chromatography to Capillary Enhanced Raman Spectroscopy for the Analysis of Proteins and Biopharmaceutical Drug Products by Thissen, Jana, Klassen, Martin D, Constantinidis, Philipp, Hacker, Michael C, Breitkreutz, Jörg, Teutenberg, Thorsten, Fischer, Björn

“…The online coupling of size exclusion chromatography (SEC) to capillary enhanced Raman spectroscopy (CERS) based on a liquid core waveguide (LCW) flow cell was…”
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Development of a Two-dimensional Liquid Chromatography High-Resolution Mass Spectrometry Method for the Characterization of Monoclonal Antibodies in Cell-Free Culture Supernatant via FcR Affinity Chromatography by Reinders, Lars M. H., Klassen, Martin D., Endres, Patrick, Krumm, Andrea, Jaeger, Martin, Schmidt, Torsten C., Teutenberg, Thorsten

“…A monoclonal antibody’s (mAb) glycosylation pattern has a significant impact on its binding affinity to the FcγRIIIa receptor and thus on antibody-dependent…”
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Quality Control of Personalized Drug Products - Identity and Quantity of Monoclonal Antibodies as Active Pharmaceutical Ingredient by Reinders, Lars M H, Klassen, Martin D, Jaeger, Martin, Schmidt, Torsten C, Teutenberg, Thorsten, Tuerk, Jochen

“…Deliberate underdosing occurred in personalized preparations of drugs such as monoclonal antibodies as the active pharmaceutical ingredient in the past. To…”
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Comparison of originator and biosimilar monoclonal antibodies using HRMS, Fc affinity chromatography, and 2D-HPLC by Reinders, Lars M. H., Klassen, Martin D., Teutenberg, Thorsten, Jaeger, Martin, Schmidt, Torsten C.

“…Due to the complex manufacturing process of therapeutic monoclonal antibodies, it is hardly possible to produce an identical copy of the original product…”
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Development of a multidimensional online method for the characterization and quantification of monoclonal antibodies using immobilized flow-through enzyme reactors by Reinders, Lars M. H., Klassen, Martin D., Teutenberg, Thorsten, Jaeger, Martin, Schmidt, Torsten C.

“…Complete characterization and quantification of monoclonal antibodies often rely on enzymatic digestion with trypsin. In order to accelerate and automate this…”
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Development and validation of a method for airborne monoclonal antibodies to quantify workplace exposure by Reinders, Lars M.H., Noelle, Dennis, Klassen, Martin D., Jaeger, Martin, Schmidt, Torsten C., Tuerk, Jochen, Teutenberg, Thorsten

“…Modern therapy strategies are based on patient-specific treatment where the drug and dose are optimally adapted to the patient's needs. In recent drugs,…”
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Quality control of cytostatic drug preparations—comparison of workflow and performance of Raman/UV and high-performance liquid chromatography coupled with diode array detection (HPLC-DAD) by Reinders, Lars M. H., Klassen, Martin D., vom Eyser, Claudia, Teutenberg, Thorsten, Jaeger, Martin, Schmidt, Torsten C., Tuerk, Jochen

“…The drugs used for treatment during chemotherapy are manufactured individually for each patient in specialised pharmacies. Thorough quality control to confirm…”
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In-use stability of ready-to-administer daratumumab subcutaneous injection solution in plastic syringes by Knoll, Laura, Thiesen, Judith, Klassen, Martin D, Reinders, Lars M H, Tuerk, Jochen, Kraemer, Irene

“…ObjectiveIn multiple myeloma patients, daratumumab is preferably injected subcutaneously. The summary of product characteristics of daratumumab subcutaneous…”
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Development of an analytical method to assess the occupational health risk of therapeutic monoclonal antibodies using LC-HRMS by Reinders, Lars M. H., Klassen, Martin D., Jaeger, Martin, Teutenberg, Thorsten, Tuerk, Jochen

“…Monoclonal antibodies are a group of commonly used therapeutics, whose occupational health risk is still discussed controversially. The long-term low-dose…”
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Towards Universal Unfolding of Detector Effects in High-Energy Physics using Denoising Diffusion Probabilistic Models by Pazos, Camila, Aeron, Shuchin, Beauchemin, Pierre-Hugues, Croft, Vincent, Klassen, Martin, Wongjirad, Taritree

“…The unfolding of detector effects in experimental data is critical for enabling precision measurements in high-energy physics. However, traditional unfolding…”
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Universal Properties of Pseudoscalar Mediators by Bauer, Martin, Klassen, Martin, Tenorth, Valentin

“…We discuss universal signals of consistent models of pseudoscalar mediators for collider searches for Dark Matter. Keeping only the degrees of freedom that can…”
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The Nobility and the Making of the Hussite Revolution by Cook, William R.

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