Search Results - "Klarmann, Ute"

Long‐term incidence of upper extremity venous obstruction in implantable cardioverter defibrillator patients by Horlbeck, Fritz W., Eckerth, Christopher, Linhart, Markus, Schaefer, Christian, Jakob, Mark, Pingel, Simon, Klarmann‐Schulz, Ute, Nickenig, Georg, Schwab, Joerg O.

“…Background Very little is known about the long‐term prevalence of severe venous obstruction and occlusion in patients with transvenous implantable…”
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Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels by Arndts, Kathrin, Specht, Sabine, Debrah, Alexander Y, Tamarozzi, Francesca, Klarmann Schulz, Ute, Mand, Sabine, Batsa, Linda, Kwarteng, Alexander, Taylor, Mark, Adjei, Ohene, Martin, Coralie, Layland, Laura E, Hoerauf, Achim

“…Mass drug administration (MDA) programmes against Onchocerca volvulus use ivermectin (IVM) which targets microfilariae (MF), the worm's offspring. Most…”
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Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti by Arndts, Kathrin, Deininger, Susanne, Specht, Sabine, Klarmann, Ute, Mand, Sabine, Adjobimey, Tomabu, Debrah, Alexander Y, Batsa, Linda, Kwarteng, Alexander, Epp, Christian, Taylor, Mark, Adjei, Ohene, Layland, Laura E, Hoerauf, Achim

“…In order to guarantee the fulfillment of their complex lifecycle, adult filarial nematodes release millions of microfilariae (MF), which are taken up by…”
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Occurrence of Lymphatic Filariasis infection after 15 years of mass drug administration in two hotspot districts in the Upper East Region of Ghana by Adu Mensah, Derrick, Debrah, Linda Batsa, Gyamfi, Peter Akosah, Rahamani, Abu Abudu, Opoku, Vera Serwaa, Boateng, John, Obeng, Prince, Osei-Mensah, Jubin, Kroidl, Inge, Klarmann-Schulz, Ute, Hoerauf, Achim, Debrah, Alexander Yaw

“…BACKGROUNDLymphatic filariasis (LF) causes chronic morbidity, which usually manifests as lymphedema or hydrocele. Mass drug administration (MDA) began in…”
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Tropical leg lymphedema caused by podoconiosis is associated with increased colonisation by anaerobic bacteria by Neidhöfer, Claudio, Nkwetta, Derick Lekealem, Fuen, Bangsi Rose, Yenban, Njodzeka Flora, Mbiatong, Nancielle, Nchanji, Gordon Takop, Korir, Patricia, Wetzig, Nina, Sieber, Martin, Thiele, Ralf, Parcina, Marijo, Klarmann-Schulz, Ute, Hoerauf, Achim, Wanji, Samuel, Ritter, Manuel

“…The non-filarial and non-communicable disease podoconiosis affects around 4 million people and is characterized by severe leg lymphedema accompanied with…”
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Macrofilaricidal Activity and Amelioration of Lymphatic Pathology in Bancroftian Filariasis after 3 Weeks of Doxycycline Followed by Single-Dose Diethylcarbamazine by Mand, Sabine, Pfarr, Kenneth, Sahoo, Prakash K, Satapathy, Ashok K, Specht, Sabine, Klarmann, Ute, Debrah, Alexander Y, Ravindran, Balachandran, Hoerauf, Achim

“…In a placebo controlled trial, the effects of 21- and 10-day doxycycline treatments (200 mg/day) followed by single dose diethylcarbamazine (administered 4…”
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The design and development of a study protocol to investigate Onchocerca volvulus, Loa loa and Mansonella perstans-mediated modulation of the metabolic and immunological profile in lean and obese individuals in Cameroon by Lenz, Benjamin, Andrew, Beng Amuam, Ritter, Manuel, Karunakaran, Indulekha, Gandjui, Narcisse Victor Tchamatchoua, Nchang, Lucy Cho, Surendar, Jayagopi, Ebob, Anita Obi Bate, Ehrens, Alexandra, Klarmann-Schulz, Ute, Ricchiuto, Arcangelo, Kuehlwein, Janina M, Fombad, Fanny Fri, Ngwa, Ambe Marius, Katcho, Tatiana Djikeussi, Hoerauf, Achim, Wanji, Samuel, Hübner, Marc P

“…Life-style metabolic diseases are steadily rising, not only in developed countries, but also in low- and middle-income countries, presenting a global health…”
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Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial by Klarmann-Schulz, Ute, Specht, Sabine, Debrah, Alexander Yaw, Batsa, Linda, Ayisi-Boateng, Nana Kwame, Osei-Mensah, Jubin, Mubarik, Yusif, Konadu, Peter, Ricchiuto, Arcangelo, Fimmers, Rolf, Arriens, Sandra, Dubben, Bettina, Ford, Louise, Taylor, Mark, Hoerauf, Achim

“…The search for new macrofilaricidal drugs against onchocerciasis that can be administered in shorter regimens than required for doxycycline (DOX, 200mg/d given…”
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The viability of utilising phone-based text messages in data capture and reporting morbidities due to lymphatic Filariasis by community health workers: a qualitative study in Kilwa district, Tanzania by Kalinga, Akili, Munga, Michael, Ngenya, Abdallah, John, Winfrida, Kisoka, William, Oriyo, Ndekya, Mutalemwa, Prince, Mandara, Wilfred, Masagati, Leonard, Ogondiek, John, Korir, Patricia, Klarmann-Schulz, Ute, Horn, Sacha, Kroidl, Inge, Debrah, Alex, Hoerauf, Achim, Mwingira, Upendo

“…Background Globally, there is recognition of the value of using mobile phones among health providers in improving health systems performance. However, in many…”
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Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti-wolbachial treatment of the human host by Albers, Anna, Esum, Mathias Eyong, Tendongfor, Nicholas, Enyong, Peter, Klarmann, Ute, Wanji, Samuel, Hoerauf, Achim, Pfarr, Kenneth

“…BACKGROUND: The human parasite Onchocerca volvulus harbours Wolbachia endosymbionts essential for worm embryogenesis, larval development and adult survival. In…”
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Phenotypical characterization, and antibiotics susceptibility patterns of skin bacteria found in podoconiosis patients in the North West Region of Cameroon by Nkwetta, Derick Lekealem, Fuen, Bangsi Rose, Yenban, Njodzeka Flora, Mbiatong, Nancielle, Nchanji, Gordon Takop, Bonekeh, John, Ndzeshang, Bertrand Lontum, Gandjui, Narcisse Victor Tchamatchoua, Fombad, Fanny Fri, Klarmann-Schulz, Ute, Esum, Mathias Eyong, Njouendou, Abdel Jelil, Cho, Jerome Fru, Hoerauf, Achim, Ritter, Manuel, Wanji, Samuel

“…Podoconiosis, a non-infectious disease originating from long-term exposure of bare feet to irritant red clay soil is a lifelong, disabling disease with no…”
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Morbidity management and surveillance of lymphatic filariasis disease and acute dermatolymphangioadenitis attacks using a mobile phone-based tool by community health volunteers in Ghana by Debrah, Linda Batsa, Mohammed, Aliyu, Osei-Mensah, Jubin, Mubarik, Yusif, Agbenyega, Olivia, Ayisi-Boateng, Nana Kwame, Pfarr, Kenneth, Kuehlwein, Janina Melanie, Klarmann-Schulz, Ute, Hoerauf, Achim, Debrah, Alexander Yaw

“…Morbidity burden of lymphatic filariasis (LF) relies on the information from the Mass Drug Administration (MDA) programme where Community Health Volunteers…”
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Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model by Specht, Sabine, Pfarr, Kenneth M, Arriens, Sandra, Hübner, Marc P, Klarmann-Schulz, Ute, Koschel, Marianne, Sternberg, Sonja, Martin, Coralie, Ford, Louise, Taylor, Mark J, Hoerauf, Achim

“…Filarial parasites can be targeted by antibiotic treatment due to their unique endosymbiotic relationship with Wolbachia bacteria. This finding has led to…”
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The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis by Horton, John, Klarmann-Schulz, Ute, Stephens, Mariana, Budge, Philip J, Coulibaly, Yaya, Debrah, Alex, Debrah, Linda Batsa, Krishnasastry, Suma, Mwingira, Upendo, Ngenya, Abdallah, Wanji, Samuel, Weerasooriya, Mirani, Yahathugoda, Channa, Kroidl, Inge, Deathe, Drew, Majewski, Andrew, Sullivan, Sarah, Mackenzie, Charles, Nutman, Thomas B, Shott, Joseph P, Weil, Gary, Ottesen, Eric, Hoerauf, Achim

“…As new lymphatic filariasis infections are eliminated through mass chemotherapy, previously affected individuals are left with the sequellae, especially…”
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Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy by Fischer, Kerstin, Dubben, Bettina, Debrah, Linda B, Kuehlwein, Janina M, Ricchiuto, Arcangelo, Debrah, Alexander Y, Hoerauf, Achim, Weil, Gary J, Fischer, Peter U, Klarmann-Schulz, Ute

“…Novel drugs or drug combinations that kill or permanently sterilize adult worms would be very helpful for treatment and elimination of onchocerciasis. In…”
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Macrofilaricidal Activity in Wuchereria bancrofti after 2 Weeks Treatment with a Combination of Rifampicin plus Doxycycline by Pfarr, Kenneth, Adjei, Ohene, Hoerauf, Achim, Debrah, Alexander Yaw, Klarmann, Ute, Specht, Sabine, Albers, Anna, Mand, Sabine, Marfo-Debrekyei, Yeboah, Batsa, Linda

“…Infection with the filarial nematode Wuchereria bancrofti can lead to lymphedema, hydrocele, and elephantiasis. Since adult worms cause pathology in lymphatic…”
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Efficacy and Safety of Adding 6 Weeks of Doxycycline to the Essential Package of Care to Treat Filarial Lymphedema: A Double-Blind, Randomized, Controlled Trial in Southern India by Krishnasastry, Suma, Ashok, Anuja, Devidas, Ammu, Sullivan, Sarah, Stephens, Mariana, Norman, Jayla, Paljug, Elianna, Deathe, Andrew, Majewski, Andrew, Horton, John, Shott, Joseph P, Klarmann-Schultz, Ute, Hoerauf, Achim, Ottesen, Eric, Mackenzie, Charles D

“…Finding additional ways to manage lymphedema due to lymphatic filariasis (LF) is a primary concern for the Global Program to Eliminate Lymphatic Filariasis…”
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Stage-Dependent Increase of Systemic Immune Activation and CCR5 + CD4 + T Cells in Filarial Driven Lymphedema in Ghana and Tanzania by Rahamani, Abu Abudu, Horn, Sacha, Ritter, Manuel, Feichtner, Anja, Osei-Mensah, Jubin, Serwaa Opoku, Vera, Batsa Debrah, Linda, Marandu, Thomas F, Haule, Antelmo, Mhidze, Jacklina, Ngenya, Abdallah, Demetrius, Max, Klarmann-Schulz, Ute, Hoelscher, Michael, Geldmacher, Christof, Hoerauf, Achim, Kalinga, Akili, Debrah, Alexander Y, Kroidl, Inge

“…Chronic lymphedema caused by infection of is a disfiguring disease that leads to physical disability, stigmatization, and reduced quality of life. The…”
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Real-time PCR detection of the HhaI tandem DNA repeat in pre- and post-patent Brugia malayi Infections: a study in indonesian transmigrants by Albers, Anna, Sartono, Erliyani, Wahyuni, Sitti, Yazdanbakhsh, Maria, Maizels, Rick M, Klarmann-Schulz, Ute, Pfarr, Kenneth, Hoerauf, Achim

“…BACKGROUND: Lymphatic filariasis caused by Wuchereria bancrofti or Brugia spp. is a public health problem in developing countries. To monitor bancroftian…”
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Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals by Arndts, Kathrin, Klarmann-Schulz, Ute, Batsa, Linda, Debrah, Alexander Y, Epp, Christian, Fimmers, Rolf, Specht, Sabine, Layland, Laura E, Hoerauf, Achim

“…37 million individuals are currently infected with Onchocerca volvulus (O. volvulus), a parasitic nematode that elicits various dermal manifestations and eye…”
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