Search Results - "Klapperich, Catherine M"

Low concentration DNA extraction and recovery using a silica solid phase by Katevatis, Constantinos, Fan, Andy, Klapperich, Catherine M

“…DNA extraction from clinical samples is commonly achieved with a silica solid phase extraction column in the presence of a chaotrope. Versions of these…”
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A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples by Rodriguez, Natalia M, Wong, Winnie S, Liu, Lena, Dewar, Rajan, Klapperich, Catherine M

“…Paper diagnostics have successfully been employed to detect the presence of antigens or small molecules in clinical samples through immunoassays; however, the…”
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Recent advances in gold electrode fabrication for low-resource setting biosensing by Zamani, Marjon, Klapperich, Catherine M, Furst, Ariel L

“…Gold electrodes are some of the most prevalent electrochemical biosensor substrate materials because they are readily functionalized with thiolated…”
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Paper-Based RNA Extraction, in Situ Isothermal Amplification, and Lateral Flow Detection for Low-Cost, Rapid Diagnosis of Influenza A (H1N1) from Clinical Specimens by Rodriguez, Natalia M, Linnes, Jacqueline C, Fan, Andy, Ellenson, Courtney K, Pollock, Nira R, Klapperich, Catherine M

“…The 2009 Influenza A (H1N1) pandemic disproportionately affected the developing world and highlighted the key inadequacies of traditional diagnostic methods…”
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Evaporative Concentration on a Paper-Based Device to Concentrate Analytes in a Biological Fluid by Wong, Sharon Y, Cabodi, Mario, Rolland, Jason, Klapperich, Catherine M

“…We report the first demonstration of using heat on a paper device to rapidly concentrate a clinically relevant analyte of interest from a biological fluid. Our…”
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Clinically Relevant Microfluidic Magnetophoretic Isolation of Rare-Cell Populations for Diagnostic and Therapeutic Monitoring Applications by Plouffe, Brian D., Mahalanabis, Madhumita, Lewis, Laura H., Klapperich, Catherine M., Murthy, Shashi K.

“…Cells of biomedical interest are, despite their functional significance, often present in very small numbers. Therefore the analysis and isolation of…”
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Surface Requirements for Optimal Biosensing with Disposable Gold Electrodes by Zamani, Marjon, Yang, Victoria, Maziashvili, Lizi, Fan, Gang, Klapperich, Catherine M, Furst, Ariel L

“…Electrochemical biosensors are promising technologies for detection and monitoring in low-resource settings due to their potential for easy use and low-cost…”
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Comparison of anterior nares CT values in asymptomatic and symptomatic individuals diagnosed with SARS-CoV-2 in a university screening program by Hall, Samantha M, Landaverde, Lena, Gill, Christopher J, Yee, Grace M, Sullivan, Madison, Doucette-Stamm, Lynn, Landsberg, Hannah, Platt, Judy T, White, Laura, Hamer, Davidson H, Klapperich, Catherine M

“…At our university based high throughput screening program, we test all members of our community weekly using RT-qPCR. RT-qPCR cycle threshold (CT) values are…”
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Cell lysis and DNA extraction of gram-positive and gram-negative bacteria from whole blood in a disposable microfluidic chip by Mahalanabis, Madhumita, Al-Muayad, Hussam, Kulinski, M Dominika, Altman, Dave, Klapperich, Catherine M

“…Sepsis caused by gram positive and gram negative bacteria is the leading cause of death in noncoronary ICUs and the tenth leading cause of death in the United…”
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Low cost extraction and isothermal amplification of DNA for infectious diarrhea diagnosis by Huang, Shichu, Do, Jaephil, Mahalanabis, Madhumita, Fan, Andy, Zhao, Lei, Jepeal, Lisa, Singh, Satish K, Klapperich, Catherine M

“…In order to counter the common perception that molecular diagnostics are too complicated to work in low resource settings, we have performed a difficult sample…”
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Electrochemical Strategy for Low-Cost Viral Detection by Zamani, Marjon, Robson, James M, Fan, Andy, Bono, Michael S, Furst, Ariel L, Klapperich, Catherine M

“…Sexually transmitted infections, including the human immunodeficiency virus (HIV) and the human papillomavirus (HPV), disproportionally impact those in…”
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Thermoplastic Microfluidic Device for On-Chip Purification of Nucleic Acids for Disposable Diagnostics by Bhattacharyya, Arpita, Klapperich, Catherine M

“…A polymeric microfluidic device for solid-phase extraction (SPE)-based isolation of nucleic acids is demonstrated. The plastic chip can function as a…”
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Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens by Cao, Qingqing, Mahalanabis, Madhumita, Chang, Jessie, Carey, Brendan, Hsieh, Christopher, Stanley, Ahjegannie, Odell, Christine A, Mitchell, Patricia, Feldman, James, Pollock, Nira R, Klapperich, Catherine M

“…A rapid, low cost, accurate point-of-care (POC) device to detect influenza virus is needed for effective treatment and control of both seasonal and pandemic…”
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Mechanical and chemical analysis of plasma and ultraviolet-ozone surface treatments for thermal bonding of polymeric microfluidic devices by Bhattacharyya, Arpita, Klapperich, Catherine M

“…Here we have demonstrated that radio frequency plasma and ultraviolet-ozone (UVO) surface modifications are effective treatments for enabling the thermal…”
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Rapid point-of-care concentration of bacteria in a disposable microfluidic device using meniscus dragging effect by Zhang, Jane Yuqian, Do, Jaephil, Premasiri, W Ranjith, Ziegler, Lawrence D, Klapperich, Catherine M

“…We report a low cost, disposable polymer microfluidic sample preparation device to perform rapid concentration of bacteria from liquid samples using enhanced…”
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Surface Immobilized Nucleic Acid–Transcription Factor Quantum Dots for Biosensing by Chen, Mingfu, Nguyen, Thuy T., Varongchayakul, Nitinun, Grazon, Chloé, Chern, Margaret, Baer, R. C., Lecommandoux, Sébastien, Klapperich, Catherine M., Galagan, James E., Dennis, Allison M., Grinstaff, Mark W.

“…Immobilization of biosensors on surfaces is a key step toward development of devices for real‐world applications. Here the preparation, characterization, and…”
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Enabling the Development and Deployment of Next Generation Point-of-Care Diagnostics by Derda, Ratmir, Gitaka, Jesse, Klapperich, Catherine M, Mace, Charles R, Kumar, Ashok A, Lieberman, Marya, Linnes, Jacqueline C, Jores, Joerg, Nasimolo, Johnson, Ndung'u, Joseph, Taracha, Evans, Weaver, Abigail, Weibel, Douglas B, Kariuki, Thomas M, Yager, Paul

“…  African participants were affiliated with universities (41 from Nairobi, Kenyatta, Makerere, Egerton, Aga Khan, Strathmore, and others), hospitals and…”
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Improving gonorrhoea molecular diagnostics: Genome mining-based identification of identical multi-repeat sequences (IMRS) in Neisseria gonorrhoeae by Shiluli, Clement, Kamath, Shwetha, Kanoi, Bernard N., Kimani, Racheal, Maina, Michael, Waweru, Harrison, Kamita, Moses, Ndirangu, Ibrahim, Abkallo, Hussein M., Oduor, Bernard, Pamme, Nicole, Dupaty, Joshua, Klapperich, Catherine M., Lolabattu, Srinivasa Raju, Gitaka, Jesse

“…Curable sexually transmitted infections (STIs), such as Neisseria gonorrhoeae (N. gonorrhoeae), are a major cause of poor pregnancy outcomes. The infection is…”
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Awareness, Interest, and Preferences of Primary Care Providers in Using Point-of-Care Cancer Screening Technology by Kim, Chloe S, Vanture, Sarah, Cho, Margaret, Klapperich, Catherine M, Wang, Catharine, Huang, Franklin W

“…Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both developed and developing…”
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Paper-Based Progesterone Sensor Using an Allosteric Transcription Factor by Zamani, Marjon, Dupaty, Josh, Baer, R. C, Kuzmanovic, Uros, Fan, Andy, Grinstaff, Mark W, Galagan, James E, Klapperich, Catherine M

“…Progesterone monitoring is an essential component of in vitro fertilization treatments and reproductive management of dairy cows. Gold-standard biosensors for…”
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